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| | MCM3 | DNA helicase; Belongs to the MCM family. (810 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (898 aa) |
| | FBH1 | F-box DNA helicase 1. (1012 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | SMARCAD1 | Uncharacterized protein. (1032 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (971 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | WRNIP1 | WRN helicase interacting protein 1. (568 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2996 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (465 aa) |
| | POT1 | Protection of telomeres 1. (652 aa) |
| | GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) |
| | CHD9 | Chromodomain helicase DNA binding protein 9. (2804 aa) |
| | DHX9 | DExH-box helicase 9. (1373 aa) |
| | LOC100715543 | DEAD-box helicase 1. (502 aa) |
| | Mcm8 | MCM domain-containing protein; Belongs to the MCM family. (833 aa) |
| | Tm4sf19 | Uncharacterized protein. (232 aa) |
| | CDC45 | Cell division cycle 45. (566 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (739 aa) |
| | GINS3 | GINS complex subunit 3. (216 aa) |
| | SUB1 | SUB1 regulator of transcription. (127 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1021 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (989 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1927 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (486 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | DERPC | DERPC proline and glycine rich nuclear protein. (531 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (731 aa) |
| | DQX1 | DEAQ-box RNA dependent ATPase 1. (719 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2003 aa) |
| | RFC5 | Replication factor C subunit 5. (340 aa) |
| | HELB | DNA helicase B. (1063 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (751 aa) |
| | LOC100721277 | Uncharacterized protein. (681 aa) |
| | SUPV3L1 | Suv3 like RNA helicase. (786 aa) |
| | CHTF18 | Chromosome transmission fidelity factor 18. (988 aa) |
| | ASCC3 | Activating signal cointegrator 1 complex subunit 3. (2185 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | Rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1246 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (706 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | RECQL4 | RecQ like helicase 4. (1226 aa) |
| | CHD6 | Chromodomain helicase DNA binding protein 6. (2716 aa) |
| | TREX1 | Three prime repair exonuclease 1. (314 aa) |
| | NAV2 | Neuron navigator 2. (2385 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1109 aa) |
| | RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (650 aa) |
| | MAML1 | Mastermind like transcriptional coactivator 1. (794 aa) |
| | HELQ | Helicase, POLQ like. (1054 aa) |
| | CHD1L | Chromodomain helicase DNA binding protein 1 like. (897 aa) |
| | RFC3 | Replication factor C subunit 3. (220 aa) |
| | Chd4 | Uncharacterized protein. (1900 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (463 aa) |
| | ATRX | ATRX chromatin remodeler. (2481 aa) |
| | DHX36 | DEAH-box helicase 36. (916 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (657 aa) |
| | HFM1 | Helicase for meiosis 1. (1400 aa) |
| | IGHMBP2 | Immunoglobulin mu DNA binding protein 2. (1051 aa) |
| | DHX32 | DEAH-box helicase 32 (putative). (724 aa) |
| | CHD2 | Uncharacterized protein. (1689 aa) |
| | C17orf64 | Chromosome 17 open reading frame 64. (220 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1117 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | DDX11 | DEAD/H-box helicase 11. (878 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (609 aa) |
| | SLFNL1 | Schlafen like 1. (371 aa) |
| | SSBP1 | Single stranded DNA binding protein 1. (137 aa) |
| | CHD1 | Chromodomain helicase DNA binding protein 1. (1666 aa) |
| | WRN | WRN RecQ like helicase. (1462 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2583 aa) |
| | Rad50 | Zinc-hook domain-containing protein. (1275 aa) |
| | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (781 aa) |
| | BLM | BLM RecQ like helicase. (1405 aa) |
| | FANCM | FA complementation group M. (1971 aa) |
| | TWNK | Twinkle mtDNA helicase. (670 aa) |
