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KCNH1 KCNH1 DDN DDN GABRG2 GABRG2 GABRA3 GABRA3 GABRA1 GABRA1 HCN1 HCN1 GRIA1 GRIA1 GABRG1 GABRG1 STX4 STX4 ATF4 ATF4 H0VVJ6_CAVPO H0VVJ6_CAVPO UNC5A UNC5A ROBO2 ROBO2 GABRA2 GABRA2 ATP2B2 ATP2B2 KCNC3 KCNC3 H0W649_CAVPO H0W649_CAVPO GABRE GABRE HCN2 HCN2 SHISA8 SHISA8 GABBR1 GABBR1 ATP2B1 ATP2B1 SHISA9 SHISA9 GPER1 GPER1 SHISA7 SHISA7 GRIN1 GRIN1 VEZT VEZT ENSCPOP00000027148 ENSCPOP00000027148 PPP1R9B PPP1R9B KCNB1 KCNB1 SPTBN1 SPTBN1 KCNC2 KCNC2 OPRD1 OPRD1 Chrna7 Chrna7 LOC100723205 LOC100723205 ANK1 ANK1 LAMP5 LAMP5 MPP2 MPP2 MYO1C MYO1C SGCE SGCE MAPK8IP3 MAPK8IP3 GABRA5 GABRA5 ATP6AP2 ATP6AP2 Mapt Mapt INSR INSR DAGLA DAGLA KCNC4 KCNC4 WLS WLS THY1 THY1 KCNC1 KCNC1 TRPV1 TRPV1 ROBO1 ROBO1 ITGA8 ITGA8 GABRA6 GABRA6 H0VF00_CAVPO H0VF00_CAVPO GABRA4 GABRA4 RIPOR2 RIPOR2 SLC1A2 SLC1A2 USH2A USH2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNH1Uncharacterized protein. (989 aa)
DDNDendrin. (709 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (505 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (671 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (861 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (384 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (298 aa)
ATF4Activating transcription factor 4. (354 aa)
H0VVJ6_CAVPOUncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (1247 aa)
UNC5AUnc-5 netrin receptor A. (898 aa)
ROBO2Roundabout guidance receptor 2. (1509 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (729 aa)
H0W649_CAVPOVoltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (783 aa)
SHISA8Shisa family member 8. (301 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (844 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
SHISA9Shisa family member 9. (424 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
SHISA7Shisa family member 7. (377 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
VEZTVezatin, adherens junctions transmembrane protein. (768 aa)
ENSCPOP00000027148Uncharacterized protein. (278 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (821 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (418 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
Chrna7Uncharacterized protein. (483 aa)
LOC100723205Death domain-containing protein. (231 aa)
ANK1Ankyrin 1. (1911 aa)
LAMP5Lysosomal associated membrane protein family member 5. (280 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (569 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1078 aa)
SGCESarcoglycan epsilon. (401 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1337 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
MaptMicrotubule-associated protein. (370 aa)
INSRTyrosine-protein kinase receptor. (1371 aa)
DAGLADiacylglycerol lipase alpha. (1037 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (594 aa)
WLSWnt ligand secretion mediator. (541 aa)
THY1Thy-1 protein. (161 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits [...] (839 aa)
ROBO1Roundabout guidance receptor 1. (1612 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
H0VF00_CAVPOUncharacterized protein. (323 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (576 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1062 aa)
SLC1A2Amino acid transporter. (573 aa)
USH2AUsherin. (5190 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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