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Pold3 | Uncharacterized protein. (466 aa) | ||||
ST18 | ST18 C2H2C-type zinc finger transcription factor. (999 aa) | ||||
KDM1B | Lysine demethylase 1B. (831 aa) | ||||
H0V4H8_CAVPO | KH domain-containing protein. (145 aa) | ||||
SLF1 | SMC5-SMC6 complex localization factor 1. (1061 aa) | ||||
DONSON | Downstream neighbor of SON. (553 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) | ||||
PRIM2 | DNA primase subunit 2. (432 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) | ||||
IRF4 | Interferon regulatory factor 4. (452 aa) | ||||
XRCC6 | X-ray repair cross complementing 6. (609 aa) | ||||
GTF2A1 | General transcription factor IIA subunit 1. (377 aa) | ||||
CTC1 | CST telomere replication complex component 1. (1206 aa) | ||||
NFYB | Nuclear transcription factor Y subunit beta. (206 aa) | ||||
MPHOSPH8 | M-phase phosphoprotein 8. (858 aa) | ||||
EPC1 | Enhancer of polycomb homolog 1. (763 aa) | ||||
ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (781 aa) | ||||
POLA1 | DNA polymerase. (1467 aa) | ||||
Pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (810 aa) | ||||
H2AZ2 | Histone H2A; Belongs to the histone H2A family. (129 aa) | ||||
RAD52 | RAD52 homolog, DNA repair protein. (280 aa) | ||||
MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa) | ||||
GINS1 | GINS complex subunit 1. (196 aa) | ||||
BRF1 | BRF1 RNA polymerase III transcription initiation factor subunit. (677 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) | ||||
RAG2 | Recombination activating 2. (527 aa) | ||||
MCM5 | DNA helicase; Belongs to the MCM family. (731 aa) | ||||
H1-1 | Histone cluster 1 H1 family member a. (215 aa) | ||||
POLD2 | DNA polymerase delta 2, accessory subunit. (469 aa) | ||||
LOC100726317 | Uncharacterized protein. (421 aa) | ||||
RPA3 | Replication protein A3. (121 aa) | ||||
POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa) | ||||
MEAF6 | MYST/Esa1 associated factor 6. (171 aa) | ||||
Ten1 | Uncharacterized protein. (122 aa) | ||||
ING3 | Inhibitor of growth protein. (418 aa) | ||||
LOC100713853 | Uncharacterized protein. (547 aa) | ||||
ESR2 | Estrogen receptor 2. (568 aa) | ||||
TERF2IP | TERF2 interacting protein. (371 aa) | ||||
VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) | ||||
DMAP1 | DNA methyltransferase 1 associated protein 1. (445 aa) | ||||
LOC106027455 | H15 domain-containing protein. (211 aa) | ||||
H2AJ | Histone H2A; Belongs to the histone H2A family. (129 aa) | ||||
LOC100728920 | Histone domain-containing protein; Belongs to the histone H2B family. (128 aa) | ||||
NKX2-5 | NK2 homeobox 5. (303 aa) | ||||
SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (737 aa) | ||||
Prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa) | ||||
TREX1 | Three prime repair exonuclease 1. (314 aa) | ||||
JUND | JunD proto-oncogene, AP-1 transcription factor subunit. (320 aa) | ||||
Parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa) | ||||
TNP1 | Transition protein 1. (55 aa) | ||||
ORC3 | Origin recognition complex subunit 3. (710 aa) | ||||
KCNIP3 | Potassium voltage-gated channel interacting protein 3. (256 aa) | ||||
LOC100735848 | TINF2_N domain-containing protein. (416 aa) | ||||
SHPRH | SNF2 histone linker PHD RING helicase. (1665 aa) | ||||
H2AZ1 | Histone H2A; Belongs to the histone H2A family. (128 aa) | ||||
RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (486 aa) | ||||
LOC100735042 | Histone domain-containing protein; Belongs to the histone H2B family. (125 aa) | ||||
LOC111756490 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
H0W7U6_CAVPO | H15 domain-containing protein. (269 aa) | ||||
MYOG | Myogenin. (249 aa) | ||||
GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) | ||||
H0W6X6_CAVPO | Uncharacterized protein. (92 aa) | ||||
SP1 | Sp1 transcription factor. (786 aa) | ||||
TBX5 | T-box transcription factor 5. (518 aa) | ||||
ZBTB17 | Zinc finger and BTB domain containing 17. (794 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4043 aa) | ||||
KDM5A | Lysine demethylase 5A. (1527 aa) | ||||
NFE2L2 | Nuclear factor, erythroid 2 like 2. (591 aa) | ||||
MAX | MYC associated factor X. (160 aa) | ||||
EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) | ||||
ENSCPOP00000028672 | annotation not available (136 aa) | ||||
LOC100712757 | TINF2_N domain-containing protein. (397 aa) | ||||
CENPA | Centromere protein A. (131 aa) | ||||
EP400 | E1A binding protein p400. (3128 aa) | ||||
H2AC20 | Histone H2A; Belongs to the histone H2A family. (110 aa) | ||||
ENSCPOP00000029061 | annotation not available (126 aa) | ||||
ENSCPOP00000029297 | annotation not available (103 aa) | ||||
MBTD1 | Mbt domain containing 1. (627 aa) | ||||
NFYC | Nuclear transcription factor Y subunit gamma. (335 aa) | ||||
LOC100734314 | annotation not available (130 aa) | ||||
ENSCPOP00000030006 | H15 domain-containing protein. (273 aa) | ||||
Morf4l1 | Mortality factor 4 like 1. (377 aa) | ||||
GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) | ||||
BRF2 | BRF2 RNA polymerase III transcription initiation factor subunit. (419 aa) | ||||
ENSCPOP00000027071 | annotation not available (130 aa) | ||||
ENSCPOP00000026982 | annotation not available (130 aa) | ||||
ATF6B | Activating transcription factor 6 beta. (694 aa) | ||||
ENSCPOP00000026646 | annotation not available (126 aa) | ||||
ENSCPOP00000026400 | annotation not available (125 aa) | ||||
SPHK2 | Sphingosine kinase 2. (655 aa) | ||||
LOC100713990 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
MACROH2A2 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) | ||||
HIST2H2AA3 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
ENSCPOP00000025603 | annotation not available (136 aa) | ||||
KAT6B | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1762 aa) | ||||
ENSCPOP00000025561 | Histone H2A; Belongs to the histone H2A family. (72 aa) | ||||
STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (375 aa) | ||||
ENSCPOP00000025402 | annotation not available (136 aa) | ||||
CDC45 | Cell division cycle 45. (566 aa) | ||||
LOC100728325 | annotation not available (103 aa) | ||||
XRCC5 | X-ray repair cross complementing 5. (739 aa) | ||||
GINS3 | GINS complex subunit 3. (216 aa) | ||||
ENSCPOP00000024875 | MRG domain-containing protein. (231 aa) | ||||
NFYA | Nuclear transcription factor Y subunit alpha. (347 aa) | ||||
LOC100714163 | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
H2BC18 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
ENSCPOP00000024582 | MRG domain-containing protein. (291 aa) | ||||
ENSCPOP00000024428 | PARP-type domain-containing protein. (104 aa) | ||||
ENSCPOP00000030090 | annotation not available (126 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1584 aa) | ||||
POT1 | Protection of telomeres 1. (652 aa) | ||||
NFE2 | Nuclear factor, erythroid 2. (373 aa) | ||||
LOC106027456 | annotation not available (126 aa) | ||||
TERF2 | Telomeric repeat binding factor 2. (542 aa) | ||||
GTF2B | General transcription factor IIB. (308 aa) | ||||
JUP | Junction plakoglobin. (745 aa) | ||||
LOC100713158 | annotation not available (128 aa) | ||||
YEATS4 | YEATS domain containing 4. (227 aa) | ||||
ENSCPOP00000032251 | annotation not available (130 aa) | ||||
LOC100734030 | annotation not available (128 aa) | ||||
HIST3H3 | Histone cluster 3 H3. (128 aa) | ||||
TONSL | Tonsoku like, DNA repair protein. (1395 aa) | ||||
LOC100730036 | Histone H3. (136 aa) | ||||
BCAS2 | BCAS2 pre-mRNA processing factor. (225 aa) | ||||
ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
ENSCPOP00000032936 | H15 domain-containing protein. (272 aa) | ||||
LOC100731150 | annotation not available (103 aa) | ||||
ENSCPOP00000024383 | annotation not available (126 aa) | ||||
HIST2H2BE | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
ENSCPOP00000024347 | annotation not available (103 aa) | ||||
ENSCPOP00000024311 | annotation not available (126 aa) | ||||
LOC100733876 | annotation not available (103 aa) | ||||
TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3860 aa) | ||||
ENSCPOP00000024231 | annotation not available (136 aa) | ||||
H3-3A | H3.3 histone A. (136 aa) | ||||
NUPR1 | Nuclear protein 1, transcriptional regulator. (90 aa) | ||||
ENSCPOP00000023894 | annotation not available (126 aa) | ||||
LOC100717510 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (396 aa) | ||||
H2AC21 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
IKZF1 | IKAROS family zinc finger 1. (511 aa) | ||||
Hhex | Homeobox domain-containing protein. (98 aa) | ||||
GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) | ||||
TCF7L2 | Transcription factor 7 like 2. (350 aa) | ||||
LOC100735272 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa) | ||||
LOC100713713 | annotation not available (130 aa) | ||||
Pold4 | Uncharacterized protein. (107 aa) | ||||
ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) | ||||
LOC100735825 | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
LOC100735546 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
LOC111756489 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) | ||||
PAX2 | Paired box 2. (393 aa) | ||||
POLD1 | DNA polymerase. (1134 aa) | ||||
Hp1bp3 | Uncharacterized protein. (520 aa) | ||||
H0VN16_CAVPO | Uncharacterized protein. (71 aa) | ||||
H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) | ||||
DDIT3 | DNA damage inducible transcript 3. (167 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa) | ||||
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (938 aa) | ||||
WDR18 | WD repeat domain 18. (429 aa) | ||||
KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2011 aa) | ||||
GLYR1 | Glyoxylate reductase 1 homolog. (553 aa) | ||||
H1-0 | H1 histone family member 0. (194 aa) | ||||
ACD | ACD shelterin complex subunit and telomerase recruitment factor. (421 aa) | ||||
MCM2 | DNA helicase; Belongs to the MCM family. (898 aa) | ||||
GTF2H3 | General transcription factor IIH subunit 3. (309 aa) | ||||
GTF2E1 | General transcription factor IIE subunit 1. (440 aa) | ||||
TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (409 aa) | ||||
RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) | ||||
TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (768 aa) | ||||
RPA2 | Replication protein A2. (270 aa) | ||||
Chd4 | Uncharacterized protein. (1900 aa) | ||||
EPC2 | Enhancer of polycomb homolog. (803 aa) | ||||
BRD8 | Bromodomain containing 8. (951 aa) | ||||
PRM1 | Sperm protamine P1; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. (49 aa) | ||||
GATA1 | GATA binding protein 1. (401 aa) | ||||
SOX12 | Transcription factor SOX. (310 aa) | ||||
H3F3B | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
MRGBP | MRG domain binding protein. (204 aa) | ||||
PRPF19 | Pre-mRNA processing factor 19. (513 aa) | ||||
TEAD4 | Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (450 aa) | ||||
LOC100725835 | Histone H2A; Belongs to the histone H2A family. (131 aa) | ||||
H1-10 | H1 histone family member X. (185 aa) | ||||
LOC101788961 | H15 domain-containing protein. (278 aa) | ||||
H1-2 | Histone cluster 1 H1 family member c. (213 aa) | ||||
LOC100722162 | Histone H2A; Belongs to the histone H2A family. (111 aa) | ||||
LOC100724929 | Histone H2A; Belongs to the histone H2A family. (117 aa) | ||||
RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |