STRINGSTRING
VPS11 VPS11 CYP7B1 CYP7B1 ZNF366 ZNF366 PHB2 PHB2 VPS18 VPS18 KANK2 KANK2 STRN3 STRN3 Brca1 Brca1 CNOT1 CNOT1 FOXH1 FOXH1 CNOT9 CNOT9 CNOT2 CNOT2 LBH LBH TP63 TP63
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (493 aa)
ZNF366Zinc finger protein 366. (779 aa)
PHB2Prohibitin. (299 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (974 aa)
KANK2KN motif and ankyrin repeat domains 2. (841 aa)
STRN3Striatin 3. (786 aa)
Brca1Uncharacterized protein. (79 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2294 aa)
FOXH1Forkhead box H1. (370 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (544 aa)
LBHProtein LBH; Transcriptional activator; Belongs to the LBH family. (105 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: medium (48%) [HD]