14 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFASC	Neurofascin. (1346 aa)
	Ank3	Uncharacterized protein. (1948 aa)
	EPB41L3	Erythrocyte membrane protein band 4.1 like 3. (938 aa)
	NCMAP	Non-compact myelin associated protein. (102 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (352 aa)
	GJC2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (405 aa)
	MAG	Myelin associated glycoprotein. (592 aa)
	SPTAN1	Spectrin alpha, non-erythrocytic 1. (2418 aa)
	SPTBN4	Spectrin beta chain; Belongs to the spectrin family. (2530 aa)
	CNTNAP1	Contactin associated protein 1. (1374 aa)
	KCNA1	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
	SCN2A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
	KIF13B	Kinesin family member 13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1831 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ank3	NFASC	ENSCPOP00000030036	ENSCPOP00000030455	Uncharacterized protein.	Neurofascin.	0.877
Ank3	SCN2A	ENSCPOP00000030036	ENSCPOP00000002443	Uncharacterized protein.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.739
Ank3	SPTAN1	ENSCPOP00000030036	ENSCPOP00000008468	Uncharacterized protein.	Spectrin alpha, non-erythrocytic 1.	0.827
Ank3	SPTBN4	ENSCPOP00000030036	ENSCPOP00000008306	Uncharacterized protein.	Spectrin beta chain; Belongs to the spectrin family.	0.969
CNTNAP1	KCNA1	ENSCPOP00000007948	ENSCPOP00000004037	Contactin associated protein 1.	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	0.461
CNTNAP1	NFASC	ENSCPOP00000007948	ENSCPOP00000030455	Contactin associated protein 1.	Neurofascin.	0.946
EPB41L3	SPTAN1	ENSCPOP00000024291	ENSCPOP00000008468	Erythrocyte membrane protein band 4.1 like 3.	Spectrin alpha, non-erythrocytic 1.	0.777
EPB41L3	SPTBN4	ENSCPOP00000024291	ENSCPOP00000008306	Erythrocyte membrane protein band 4.1 like 3.	Spectrin beta chain; Belongs to the spectrin family.	0.762
KCNA1	CNTNAP1	ENSCPOP00000004037	ENSCPOP00000007948	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	Contactin associated protein 1.	0.461
KCNA1	SCN2A	ENSCPOP00000004037	ENSCPOP00000002443	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.487
MAG	NFASC	ENSCPOP00000010924	ENSCPOP00000030455	Myelin associated glycoprotein.	Neurofascin.	0.423
NFASC	Ank3	ENSCPOP00000030455	ENSCPOP00000030036	Neurofascin.	Uncharacterized protein.	0.877
NFASC	CNTNAP1	ENSCPOP00000030455	ENSCPOP00000007948	Neurofascin.	Contactin associated protein 1.	0.946
NFASC	MAG	ENSCPOP00000030455	ENSCPOP00000010924	Neurofascin.	Myelin associated glycoprotein.	0.423
NFASC	SPTAN1	ENSCPOP00000030455	ENSCPOP00000008468	Neurofascin.	Spectrin alpha, non-erythrocytic 1.	0.471
NFASC	SPTBN4	ENSCPOP00000030455	ENSCPOP00000008306	Neurofascin.	Spectrin beta chain; Belongs to the spectrin family.	0.674
SCN2A	Ank3	ENSCPOP00000002443	ENSCPOP00000030036	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Uncharacterized protein.	0.739
SCN2A	KCNA1	ENSCPOP00000002443	ENSCPOP00000004037	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	0.487
SCN2A	SPTAN1	ENSCPOP00000002443	ENSCPOP00000008468	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Spectrin alpha, non-erythrocytic 1.	0.484
SPTAN1	Ank3	ENSCPOP00000008468	ENSCPOP00000030036	Spectrin alpha, non-erythrocytic 1.	Uncharacterized protein.	0.827