87 items (Cavia porcellus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	KLHL4	Kelch like family member 4. (595 aa)
	LATS2	Non-specific serine/threonine protein kinase. (955 aa)
	DBH	Dopamine beta-hydroxylase. (616 aa)
	MAP11	Microtubule associated protein 11. (580 aa)
	TAP1	Transporter 1, ATP binding cassette subfamily B member. (725 aa)
	NEK1	NIMA related kinase 1. (1282 aa)
	FOPNL	FGFR1OP N-terminal like. (174 aa)
	RASSF7	Ras association domain family member 7. (359 aa)
	SDCCAG8	Serologically defined colon cancer antigen 8. (714 aa)
	OFD1	OFD1 centriole and centriolar satellite protein. (996 aa)
	H0VRG5_CAVPO	Uncharacterized protein. (425 aa)
	DDHD2	DDHD domain containing 2. (668 aa)
	CCDC14	Coiled-coil domain containing 14. (902 aa)
	CEP162	Centrosomal protein 162. (1287 aa)
	ALDOB	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	SSX2IP	SSX family member 2 interacting protein. (598 aa)
	UBN1	Ubinuclein 1. (1136 aa)
	CD2AP	CD2 associated protein. (632 aa)
	PARD6A	Par-6 family cell polarity regulator alpha. (346 aa)
	C2CD3	C2 domain containing 3 centriole elongation regulator. (2326 aa)
	Ccdc13	Uncharacterized protein. (706 aa)
	FRMD8	FERM domain containing 8. (465 aa)
	DYSF	Dysferlin. (2103 aa)
	PIK3R5	Phosphoinositide-3-kinase regulatory subunit 5. (886 aa)
	FNIP2	Folliculin interacting protein 2. (1079 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (383 aa)
	CEP131	Centrosomal protein 131. (1070 aa)
	CCDC66	Coiled-coil domain containing 66. (932 aa)
	H0VDW1_CAVPO	IF rod domain-containing protein; Belongs to the intermediate filament family. (432 aa)
	CEP72	Centrosomal protein 72. (648 aa)
	MPP1	Membrane palmitoylated protein 1; Belongs to the MAGUK family. (466 aa)
	RAB11FIP3	RAB11 family interacting protein 3. (446 aa)
	CDC42BPG	CDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1544 aa)
	NEK6	NIMA related kinase 6; Belongs to the protein kinase superfamily. (313 aa)
	PIBF1	Progesterone immunomodulatory binding factor 1. (765 aa)
	PXK	PX domain containing serine/threonine kinase like. (567 aa)
	CNTRL	Centriolin. (2335 aa)
	LOC100716676	TPR_REGION domain-containing protein. (567 aa)
	TRAT1	T cell receptor associated transmembrane adaptor 1. (187 aa)
	ODF2L	Outer dense fiber of sperm tails 2 like. (549 aa)
	KCTD1	Potassium channel tetramerization domain containing 1. (265 aa)
	FLII	FLII actin remodeling protein. (1261 aa)
	DCDC2	Doublecortin domain containing 2. (469 aa)
	AK5	Adenylate kinase 5; Belongs to the adenylate kinase family. (536 aa)
	G6PD	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
	GPR174	G protein-coupled receptor 174. (333 aa)
	PCNT	Pericentrin. (2941 aa)
	KLHL12	Kelch like family member 12. (568 aa)
	RAB11FIP5	RAB11 family interacting protein 5. (636 aa)
	Bbs1	BBS1 domain-containing protein. (593 aa)
	CYTH4	Cytohesin 4. (394 aa)
	PAX2	Paired box 2. (393 aa)
	PLA2G6	Phospholipase A2 group VI. (803 aa)
	WDR62	WD repeat domain 62. (1480 aa)
	CCDC61	Coiled-coil domain containing 61. (513 aa)
	KNSTRN	Kinetochore localized astrin (SPAG5) binding protein. (231 aa)
	EXOC7	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (697 aa)
	FLOT1	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
	CENPU	Centromere protein U. (405 aa)
	HOOK3	Hook microtubule tethering protein 3. (718 aa)
	BBS9	Bardet-Biedl syndrome 9. (887 aa)
	NLRC3	NLR family CARD domain containing 3. (1086 aa)
	CEP68	Centrosomal protein 68. (745 aa)
	CFAP53	Cilia and flagella associated protein 53. (404 aa)
	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit. (238 aa)
	Spag5	Sperm associated antigen 5. (1196 aa)
	TAF1D	TATA-box binding protein associated factor, RNA polymerase I subunit D. (267 aa)
	C2CD5	C2 calcium dependent domain containing 5. (1035 aa)
	Krt18	IF rod domain-containing protein; Belongs to the intermediate filament family. (432 aa)
	CCDC113	Coiled-coil domain containing 113. (377 aa)
	ZMYND10	Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (440 aa)
	KIAA0753	KIAA0753. (963 aa)
	SPAG9	Sperm associated antigen 9. (1325 aa)
	DLGAP5	DLG associated protein 5. (815 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
	ZBED6	Zinc finger BED-type containing 6. (979 aa)
	NUDT21	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (223 aa)
	IL4R	Interleukin 4 receptor. (829 aa)
	BBS5	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...] (341 aa)
	ENSCPOP00000029916	Uncharacterized protein. (231 aa)
	RASSF8	Ras association domain family member 8. (419 aa)
	PLK1	Serine/threonine-protein kinase PLK. (604 aa)
	RBM39	Uncharacterized protein. (490 aa)
	Ccdc57	Uncharacterized protein. (998 aa)
	KCTD15	Potassium channel tetramerization domain containing 15. (283 aa)
	PCM1	Pericentriolar material 1. (2080 aa)
	CEP290	Centrosomal protein 290. (2425 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK5	LOC100716676	ENSCPOP00000002838	ENSCPOP00000004586	Adenylate kinase 5; Belongs to the adenylate kinase family.	TPR_REGION domain-containing protein.	0.413
AK5	MPP1	ENSCPOP00000002838	ENSCPOP00000007924	Adenylate kinase 5; Belongs to the adenylate kinase family.	Membrane palmitoylated protein 1; Belongs to the MAGUK family.	0.688
ALDOB	G6PD	ENSCPOP00000011144	ENSCPOP00000018715	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.877
BBS5	BBS9	ENSCPOP00000028238	ENSCPOP00000000840	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Bardet-Biedl syndrome 9.	0.996
BBS5	Bbs1	ENSCPOP00000028238	ENSCPOP00000020681	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	BBS1 domain-containing protein.	0.998
BBS5	CEP131	ENSCPOP00000028238	ENSCPOP00000008543	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Centrosomal protein 131.	0.428
BBS5	CEP290	ENSCPOP00000028238	ENSCPOP00000032712	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Centrosomal protein 290.	0.640
BBS5	CEP72	ENSCPOP00000028238	ENSCPOP00000007959	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Centrosomal protein 72.	0.497
BBS5	KLHL12	ENSCPOP00000028238	ENSCPOP00000020308	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Kelch like family member 12.	0.472
BBS5	KLHL4	ENSCPOP00000028238	ENSCPOP00000032933	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Kelch like family member 4.	0.418
BBS5	LOC100716676	ENSCPOP00000028238	ENSCPOP00000004586	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	TPR_REGION domain-containing protein.	0.985
BBS9	BBS5	ENSCPOP00000000840	ENSCPOP00000028238	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.996
BBS9	Bbs1	ENSCPOP00000000840	ENSCPOP00000020681	Bardet-Biedl syndrome 9.	BBS1 domain-containing protein.	0.999
BBS9	CEP131	ENSCPOP00000000840	ENSCPOP00000008543	Bardet-Biedl syndrome 9.	Centrosomal protein 131.	0.485
BBS9	CEP290	ENSCPOP00000000840	ENSCPOP00000032712	Bardet-Biedl syndrome 9.	Centrosomal protein 290.	0.587
BBS9	KLHL12	ENSCPOP00000000840	ENSCPOP00000020308	Bardet-Biedl syndrome 9.	Kelch like family member 12.	0.686
BBS9	KLHL4	ENSCPOP00000000840	ENSCPOP00000032933	Bardet-Biedl syndrome 9.	Kelch like family member 4.	0.774
BBS9	LOC100716676	ENSCPOP00000000840	ENSCPOP00000004586	Bardet-Biedl syndrome 9.	TPR_REGION domain-containing protein.	0.997
BBS9	PCNT	ENSCPOP00000000840	ENSCPOP00000019792	Bardet-Biedl syndrome 9.	Pericentrin.	0.411
Bbs1	BBS5	ENSCPOP00000020681	ENSCPOP00000028238	BBS1 domain-containing protein.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.998