STRINGSTRING
Kcnj3 Kcnj3 Scnn1g Scnn1g KCNQ5 KCNQ5 GRIK1 GRIK1 GRIA2 GRIA2 TRPV6 TRPV6 KCNB2 KCNB2 BEST2 BEST2 GRIA4 GRIA4 KCNK1 KCNK1 CLCC1 CLCC1 GABRA3 GABRA3 TRPC3 TRPC3 ABCC8 ABCC8 GRIN2C GRIN2C CCDC51 CCDC51 CALM2 CALM2 GRIK2 GRIK2 MICU1 MICU1 KCND3 KCND3 KCNA10 KCNA10 KCNAB3 KCNAB3 Mcub Mcub GABRG2 GABRG2 PEX5L PEX5L CALM1 CALM1 CACNG2 CACNG2 GABRD GABRD SCN1A SCN1A SCN2A SCN2A KCNAB2 KCNAB2 KCNH1 KCNH1 TRPC1 TRPC1 PKD1 PKD1 CACNB3 CACNB3 KCNC2 KCNC2 VWC2 VWC2 GRIA3 GRIA3 GRIA1 GRIA1 SCN4B SCN4B LRRC8E LRRC8E LRRC8A LRRC8A ABHD12 ABHD12 GABRA5 GABRA5 ABCB8 ABCB8 CACNA1B CACNA1B KCNA1 KCNA1 AKAP9 AKAP9 KCNAB1 KCNAB1 DPP10 DPP10 KCNQ4 KCNQ4 H0V4J9_CAVPO H0V4J9_CAVPO CACNA2D4 CACNA2D4 MICU2 MICU2 KCNV1 KCNV1 CTTN CTTN CHRND CHRND GABRB3 GABRB3 Cacnb2 Cacnb2 GRIN2B GRIN2B BEST1 BEST1 STAC3 STAC3 LRRC8B LRRC8B GRIN3A GRIN3A GABRA1 GABRA1 AKAP6 AKAP6 CLIC2 CLIC2 LRRC8D LRRC8D CHRNA9 CHRNA9 SACM1L SACM1L SCN4A SCN4A UNC80 UNC80 Atp5mc1 Atp5mc1 KCNQ3 KCNQ3 CLCN2 CLCN2 CACNA2D3 CACNA2D3 PACC1 PACC1 GABRA4 GABRA4 MICU3 MICU3 H0VF00_CAVPO H0VF00_CAVPO GLRA2 GLRA2 GABRA6 GABRA6 CHRNA6 CHRNA6 SCN3A SCN3A OSTM1 OSTM1 CHRNA4 CHRNA4 HTR3B HTR3B HTR3A HTR3A PKD2L1 PKD2L1 GABRR1 GABRR1 GABRR2 GABRR2 GABRQ GABRQ KCNC1 KCNC1 KCNJ8 KCNJ8 CNGA2 CNGA2 GRID2 GRID2 Scnn1d Scnn1d CACHD1 CACHD1 Trpc4 Trpc4 CHRNB3 CHRNB3 GRIN3B GRIN3B KCND2 KCND2 CACNA1I CACNA1I LRRTM4 LRRTM4 GLRA3 GLRA3 H0VKV0_CAVPO H0VKV0_CAVPO CACNA1H CACNA1H KCNG3 KCNG3 CATSPER3 CATSPER3 CHRNA5 CHRNA5 CHRNA3 CHRNA3 CFTR CFTR KCNC4 KCNC4 GABRR3 GABRR3 CNGB3 CNGB3 STXBP5 STXBP5 SCN9A SCN9A LOC100730761 LOC100730761 TRPC5 TRPC5 Scnn1b Scnn1b VWC2L VWC2L GRIN2A GRIN2A GLRA1 GLRA1 Kcnmb2 Kcnmb2 SCN10A SCN10A HCN1 HCN1 SCN7A SCN7A KCNIP1 KCNIP1 H0VQQ2_CAVPO H0VQQ2_CAVPO PKD2 PKD2 CLCN1 CLCN1 CHRNB1 CHRNB1 CACNA1E CACNA1E KCNIP3 KCNIP3 GABRB2 GABRB2 CACNG7 CACNG7 LRRC52 LRRC52 CPT1C CPT1C GABRG1 GABRG1 MCU MCU SCN8A SCN8A RYR1 RYR1 GLRA4 GLRA4 EFCAB9 EFCAB9 Sestd1 Sestd1 H0VVJ6_CAVPO H0VVJ6_CAVPO KCNA3 KCNA3 KCNQ1 KCNQ1 CHRNG CHRNG KCNS3 KCNS3 SLC5A3 SLC5A3 BEST4 BEST4 H0VZD4_CAVPO H0VZD4_CAVPO KCNH2 KCNH2 GRIK3 GRIK3 OLFM1 OLFM1 CACNG4 CACNG4 KCNMB3 KCNMB3 CNGA1 CNGA1 SCNN1A SCNN1A TTYH2 TTYH2 GABRA2 GABRA2 OLFM2 OLFM2 CNGA3 CNGA3 KCNS2 KCNS2 CACNA1F CACNA1F CNGA4 CNGA4 KCNC3 KCNC3 KCNF1 KCNF1 H0W649_CAVPO H0W649_CAVPO H0W682_CAVPO H0W682_CAVPO CACNA2D2 CACNA2D2 CLIC1 CLIC1 GRIK5 GRIK5 CHRNE CHRNE HCN3 HCN3 CNIH3 CNIH3 KCNA5 KCNA5 KCNK4 KCNK4 CACNA1A CACNA1A KCNJ11 KCNJ11 GABRE GABRE CHRNA10 CHRNA10 TRPC6 TRPC6 TRPM4 TRPM4 CHRNB4 CHRNB4 CACNA1G CACNA1G DLG4 DLG4 HCN4 HCN4 SCN1B SCN1B HCN2 HCN2 CACNA1S CACNA1S PTPA PTPA KCNIP2 KCNIP2 CACNA2D1 CACNA2D1 PDE4D PDE4D CACNG6 CACNG6 SHISA8 SHISA8 GABRB1 GABRB1 SCN11A SCN11A KCNMB1 KCNMB1 KCNE2 KCNE2 KCNA6 KCNA6 KCNS1 KCNS1 KCNG1 KCNG1 CACNA1C CACNA1C CACNB1 CACNB1 CACNG1 CACNG1 LOC100730738 LOC100730738 CACNG3 CACNG3 SHISA9 SHISA9 ABHD6 ABHD6 KCNE1 KCNE1 EPS8 EPS8 CLIC4 CLIC4 LRRC8C LRRC8C LRRC38 LRRC38 CLIC3 CLIC3 OLFM3 OLFM3 SCN3B SCN3B Fkbp1a Fkbp1a KCNQ2 KCNQ2 Cacnb4 Cacnb4 SCN2B SCN2B KCNG4 KCNG4 ENSCPOP00000026472 ENSCPOP00000026472 CLCN7 CLCN7 GRIN1 GRIN1 PDE4B PDE4B TRDN TRDN KCNJ5 KCNJ5 ATP5MC3 ATP5MC3 TRPC7 TRPC7 GRIN2D GRIN2D AMIGO2 AMIGO2 KCNMA1 KCNMA1 FKBP1B FKBP1B TTYH1 TTYH1 KCNA4 KCNA4 RYR2 RYR2 CALM3 CALM3 DLG3 DLG3 ANO6 ANO6 Ttyh3 Ttyh3 CLIC5 CLIC5 KCNIP4 KCNIP4 CNIH2 CNIH2 PORCN PORCN Kcng2 Kcng2 KCNA2 KCNA2 KCNB1 KCNB1 CHRNA1 CHRNA1 KCNV2 KCNV2 Chrna7 Chrna7 NRN1 NRN1 ENSCPOP00000029622 ENSCPOP00000029622 TMEM262 TMEM262 LRRC55 LRRC55 GLRB GLRB PTK2B PTK2B SMDT1 SMDT1 CHRNA2 CHRNA2 Chrnb2 Chrnb2 ENSCPOP00000030667 ENSCPOP00000030667 ABCC9 ABCC9 Kcnj2 Kcnj2 DPP6 DPP6 KCND1 KCND1 ENSCPOP00000031692 ENSCPOP00000031692 ENSCPOP00000032059 ENSCPOP00000032059 CACNA1D CACNA1D SCN5A SCN5A BEST3 BEST3 GABRP GABRP TRPV5 TRPV5 KCNK2 KCNK2 KCNA7 KCNA7 GRIK4 GRIK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Kcnj3IRK_C domain-containing protein. (194 aa)
Scnn1gUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (653 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (908 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (934 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (767 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (505 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (819 aa)
KCNK1Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa)
CLCC1Chloride channel CLIC like 1. (529 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (505 aa)
TRPC3ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (849 aa)
ABCC8ATP binding cassette subfamily C member 8. (1549 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1209 aa)
CCDC51Coiled-coil domain containing 51. (408 aa)
CALM2Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
MICU1Mitochondrial calcium uptake 1. (483 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (404 aa)
McubMCU domain-containing protein. (195 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (650 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (194 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1997 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (382 aa)
KCNH1Uncharacterized protein. (989 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4283 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (418 aa)
VWC2Von Willebrand factor C domain containing 2. (315 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (888 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (861 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (184 aa)
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (691 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
ABHD12Abhydrolase domain containing 12. (397 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ABCB8ATP binding cassette subfamily B member 8. (720 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2270 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
AKAP9A-kinase anchoring protein 9. (3887 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (401 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (776 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (699 aa)
H0V4J9_CAVPOUncharacterized protein. (291 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1101 aa)
MICU2Mitochondrial calcium uptake 2. (432 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (502 aa)
CTTNCortactin. (550 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
Cacnb2SH3 domain-containing protein. (621 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1381 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (566 aa)
STAC3SH3 and cysteine rich domain 3. (363 aa)
LRRC8BLeucine rich repeat containing 8 VRAC subunit B. (803 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1114 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
AKAP6A-kinase anchoring protein 6. (2208 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa)
LRRC8DLeucine rich repeat containing 8 VRAC subunit D. (858 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (465 aa)
SACM1LSAC1 like phosphatidylinositide phosphatase. (587 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1829 aa)
UNC80Unc-80 homolog, NALCN channel complex subunit. (3223 aa)
Atp5mc1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (860 aa)
CLCN2Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport (By similarity). Involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (By similarity); Belongs [...] (889 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (991 aa)
PACC1Proton activated chloride channel 1. (350 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (576 aa)
MICU3Mitochondrial calcium uptake family member 3. (442 aa)
H0VF00_CAVPOUncharacterized protein. (323 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa)
OSTM1Osteoclastogenesis associated transmembrane protein 1. (334 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (620 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (442 aa)
HTR3A5-hydroxytryptamine receptor 3A; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand- gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. (456 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (760 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (480 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (617 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
KCNJ8Uncharacterized protein. (468 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (663 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
Scnn1dUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (618 aa)
CACHD1Cache domain containing 1. (1272 aa)
Trpc4Transient receptor potential channel 4 alpha; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (463 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (845 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2067 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (591 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
H0VKV0_CAVPOUncharacterized protein; Belongs to the calmodulin family. (139 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2337 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (417 aa)
CATSPER3Cation channel sperm associated 3. (380 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (438 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (506 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (594 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
CNGB3Cyclic nucleotide gated channel subunit beta 3. (667 aa)
STXBP5Syntaxin binding protein 5. (1067 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa)
LOC100730761Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
Scnn1bUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (222 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1462 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
Kcnmb2KcnmB2_inactiv domain-containing protein. (235 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (671 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1520 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (227 aa)
H0VQQ2_CAVPOCyclic nucleotide-binding domain-containing protein. (852 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (839 aa)
CLCN1Chloride channel protein. (990 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (502 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (256 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
LRRC52Leucine rich repeat containing 52. (316 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (807 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (384 aa)
MCUMitochondrial calcium uniporter. (344 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1876 aa)
RYR1Ryanodine receptor 1. (4554 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
EFCAB9EF-hand calcium binding domain 9. (193 aa)
Sestd1CRAL-TRIO domain-containing protein. (696 aa)
H0VVJ6_CAVPOUncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (1247 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (528 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (515 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
SLC5A3Solute carrier family 5 member 3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (718 aa)
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (461 aa)
H0VZD4_CAVPOATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (884 aa)
OLFM1Olfactomedin 1. (483 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (325 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (270 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (507 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. Belongs to the amilori [...] (680 aa)
TTYH2Protein tweety homolog; Probable chloride channel. (533 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
OLFM2Olfactomedin 2. (457 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (647 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (445 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1774 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (574 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (729 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (435 aa)
H0W649_CAVPOVoltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa)
H0W682_CAVPOProtein tweety homolog; Probable chloride channel. (108 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1129 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (892 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (780 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (129 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (392 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2105 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (447 aa)
TRPC6Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (934 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1138 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (489 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2372 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (754 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1186 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (216 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (783 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (323 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (270 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1078 aa)
PDE4DPhosphodiesterase. (782 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (257 aa)
SHISA8Shisa family member 8. (301 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (419 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1719 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (491 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (497 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (515 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (641 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
LOC100730738Chloride channel protein. (729 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
SHISA9Shisa family member 9. (424 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (821 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
LRRC8CLeucine rich repeat containing 8 VRAC subunit C. (803 aa)
LRRC38Leucine rich repeat containing 38. (295 aa)
CLIC3Chloride intracellular channel 3. (237 aa)
OLFM3Olfactomedin 3. (478 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
Fkbp1aPeptidylprolyl isomerase. (108 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (871 aa)
Cacnb4SH3 domain-containing protein. (519 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (209 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (509 aa)
ENSCPOP00000026472Uncharacterized protein. (286 aa)
CLCN7Chloride channel protein. (804 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
PDE4BPhosphodiesterase. (736 aa)
TRDNTriadin. (682 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
ATP5MC3Mitochondrial ATP synthase lipid-binding protein isoform A; Belongs to the ATPase C chain family. (141 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (808 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1133 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
TTYH1Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (380 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (622 aa)
RYR2Ryanodine receptor 2. (4910 aa)
CALM3Calmodulin 3. (149 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (850 aa)
ANO6Anoctamin. (922 aa)
Ttyh3Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (524 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (143 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa)
Kcng2Ion_trans domain-containing protein; Belongs to the potassium channel family. (235 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (457 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (558 aa)
Chrna7Uncharacterized protein. (483 aa)
NRN1Neuritin 1. (142 aa)
ENSCPOP00000029622Uncharacterized protein. (198 aa)
TMEM262Transmembrane protein 262. (107 aa)
LRRC55Leucine rich repeat containing 55. (328 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
SMDT1Single-pass membrane protein with aspartate rich tail 1. (107 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (519 aa)
Chrnb2Uncharacterized protein. (499 aa)
ENSCPOP00000030667Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (245 aa)
ABCC9ATP binding cassette subfamily C member 9. (1546 aa)
Kcnj2Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (864 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa)
ENSCPOP00000031692CRAL-TRIO domain-containing protein. (645 aa)
ENSCPOP00000032059Uncharacterized protein; Belongs to the calmodulin family. (73 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2164 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2015 aa)
BEST3Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (673 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (469 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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