STRINGSTRING
NEDD4 NEDD4 CTNNB1 CTNNB1 LOC100732436 LOC100732436 OPHN1 OPHN1 IL1R1 IL1R1 RAPSN RAPSN FUS FUS DLG3 DLG3 SNX27 SNX27 Nsf Nsf RAB4A RAB4A SHISA7 SHISA7 FLOT1 FLOT1 SQSTM1 SQSTM1 CACNG3 CACNG3 LOC100732158 LOC100732158 DLG4 DLG4 MAP1A MAP1A H0W6Z4_CAVPO H0W6Z4_CAVPO SHANK1 SHANK1 H0W649_CAVPO H0W649_CAVPO PTEN PTEN CACNG4 CACNG4 CDK5R1 CDK5R1 SHANK3 SHANK3 ND2 ND2 FLOT2 FLOT2 GSK3B GSK3B Myo5b Myo5b NETO2 NETO2 PICK1 PICK1 SHANK2 SHANK2 H0VF00_CAVPO H0VF00_CAVPO NETO1 NETO1 DRD2 DRD2 H0VE70_CAVPO H0VE70_CAVPO GRIN2B GRIN2B CANX CANX IGSF11 IGSF11 CACNG2 CACNG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEDD4E3 ubiquitin-protein ligase. (896 aa)
CTNNB1Catenin beta 1. (781 aa)
LOC100732436Uncharacterized protein. (327 aa)
OPHN1Uncharacterized protein. (802 aa)
IL1R1Interleukin 1 receptor type 1. (572 aa)
RAPSNReceptor associated protein of the synapse. (412 aa)
FUSFUS RNA binding protein. (490 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (850 aa)
SNX27Sorting nexin 27. (541 aa)
NsfUncharacterized protein. (748 aa)
RAB4ARAB4A, member RAS oncogene family. (218 aa)
SHISA7Shisa family member 7. (377 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
SQSTM1Sequestosome 1. (415 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
LOC100732158Uncharacterized protein. (246 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (754 aa)
MAP1AMicrotubule associated protein 1A. (2915 aa)
H0W6Z4_CAVPOUncharacterized protein. (750 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1749 aa)
H0W649_CAVPOVoltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (325 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1694 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
Myo5bUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1803 aa)
NETO2Neuropilin and tolloid like 2. (520 aa)
PICK1Protein interacting with PRKCA 1. (415 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1839 aa)
H0VF00_CAVPOUncharacterized protein. (323 aa)
NETO1Neuropilin and tolloid like 1. (450 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
H0VE70_CAVPOUncharacterized protein. (796 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1381 aa)
CANXCalnexin. (593 aa)
IGSF11Immunoglobulin superfamily member 11. (420 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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