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| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (738 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (447 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | PAX8 | Paired box 8. (457 aa) |
| | GDF11 | Growth differentiation factor 11. (261 aa) |
| | CRH | Corticotropin releasing hormone. (193 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (865 aa) |
| | THRA | Thyroid hormone receptor alpha. (514 aa) |
| | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (540 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | ZBED6 | Zinc finger BED-type containing 6. (979 aa) |
| | SIX1 | SIX homeobox 1. (284 aa) |
| | CDH2 | Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa) |
| | HOXA3 | Homeobox A3. (444 aa) |
| | FOXA2 | Forkhead box A2. (459 aa) |
| | HOXD3 | Homeobox D3. (432 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | LY6E | Lymphocyte antigen 6 family member E. (136 aa) |
| | GLI2 | GLI family zinc finger 2. (1570 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | HOXA5 | Homeobox A5. (270 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | Hhex | Homeobox domain-containing protein. (98 aa) |
| | Pitx2 | Homeobox protein. (325 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (210 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (350 aa) |
| | POU1F1 | POU domain protein. (316 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (279 aa) |
| | IL6R | Interleukin 6 receptor. (450 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | H0WDZ5_CAVPO | Homeobox domain-containing protein. (154 aa) |
| | SLC6A3 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa) |
| | ASCL1 | Achaete-scute family bHLH transcription factor 1. (215 aa) |
| | NKX2-1 | Thyroid transcription factor 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis (By similarity). (344 aa) |
| | NEUROD1 | Neurogenic differentiation factor. (355 aa) |
| | Vhl | Uncharacterized protein. (182 aa) |
| | Sox4 | HMG box domain-containing protein. (227 aa) |
| | BMPR1A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa) |
| | GIP | Gastric inhibitory polypeptide. (145 aa) |
| | H0W5D5_CAVPO | DUF4074 domain-containing protein. (324 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (607 aa) |
| | NKX6-2 | NK6 homeobox 2. (267 aa) |
| | SIX3 | SIX homeobox 3. (332 aa) |
| | NKX2-5 | NK2 homeobox 5. (303 aa) |
| | Mnx1 | Homeobox domain-containing protein. (233 aa) |
| | PROP1 | PROP paired-like homeobox 1. (227 aa) |
| | SRF | Serum response factor. (461 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (308 aa) |
| | ONECUT1 | One cut domain family member. (465 aa) |
| | STRA6 | Stimulated by retinoic acid 6. (661 aa) |
| | NR5A1 | Nuclear receptor subfamily 5 group A member 1. (457 aa) |
| | NR3C1 | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (772 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | ADCYAP1 | Adenylate cyclase activating polypeptide 1. (180 aa) |
| | RFX6 | Regulatory factor X6. (896 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | BMP6 | Bone morphogenetic protein 6. (505 aa) |
| | PDE3B | Phosphodiesterase. (931 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1112 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | H0VN16_CAVPO | Uncharacterized protein. (71 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (325 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1371 aa) |
| | HESX1 | HESX homeobox 1. (185 aa) |
| | TBX1 | T-box transcription factor 1. (360 aa) |
| | TBX19 | T-box transcription factor 19. (446 aa) |
| | CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (891 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | GHRHR | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (422 aa) |
| | GCM2 | Glial cells missing transcription factor 2. (497 aa) |
| | ARMC5 | Armadillo repeat containing 5. (905 aa) |
| | PCSK1 | Proprotein convertase subtilisin/kexin type 1. (755 aa) |
| | OTP | Orthopedia homeobox. (325 aa) |
| | GATA2 | GATA binding protein 2. (374 aa) |
| | TG | Thyroglobulin. (2742 aa) |
| | CGA | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (120 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1. (383 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | GATA3 | GATA binding protein 3. (443 aa) |
| | MDK | Midkine. (143 aa) |
| | DUOX2 | Dual oxidase 2. (1517 aa) |
| | PAX6 | Paired box 6. (436 aa) |
| | LHX3 | LIM homeobox 3. (403 aa) |
| | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (518 aa) |
| | SIDT2 | SID1 transmembrane family member 2. (853 aa) |
| | BMP4 | Bone morphogenetic protein 4. (404 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | MYT1 | Myelin transcription factor 1. (1159 aa) |
| | SALL1 | Spalt like transcription factor 1. (1287 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (347 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | PAX4 | Paired box 4. (337 aa) |
| | NF1 | Neurofibromin 1. (2750 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) |
| | PBX1 | PBX homeobox 1. (430 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | H0V5P5_CAVPO | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (385 aa) |
| | GLI1 | GLI family zinc finger 1. (1104 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (114 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (550 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PAX1 | Paired box 1. (401 aa) |
| | MEN1 | Menin 1. (615 aa) |
| | HNF1B | HNF1 homeobox B. (558 aa) |
| | RFX3 | Regulatory factor X3. (724 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (214 aa) |
| | PITX1 | Homeobox protein. (311 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | WT1 | WT1 transcription factor. (320 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | INHBB | Inhibin subunit beta B. (374 aa) |
| | ARID5B | AT-rich interaction domain 5B. (1194 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (264 aa) |
