18 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	LOC100713873	Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa)
	LOC100713317	Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa)
	Cd8b	CD8 beta. (210 aa)
	LOC100723960	Ig-like domain-containing protein; Belongs to the MHC class I family. (453 aa)
	PDIA3	Protein disulfide-isomerase. (505 aa)
	BCAP31	B cell receptor associated protein 31. (246 aa)
	ATP5F1A	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (527 aa)
	TAP1	Transporter 1, ATP binding cassette subfamily B member. (725 aa)
	ATP5F1B	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (487 aa)
	Tap2	Uncharacterized protein. (703 aa)
	LOC100723644	C-type lectin domain-containing protein. (222 aa)
	TUBB	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	LOC100722817	C-type lectin domain-containing protein. (225 aa)
	MFSD6	Major facilitator superfamily domain containing 6. (797 aa)
	Pilra	Ig-like domain-containing protein. (291 aa)
	DERL1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
	Cd244	Ig-like domain-containing protein. (345 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5F1A	ATP5F1B	ENSCPOP00000011443	ENSCPOP00000016071	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ATP5F1A	VCP	ENSCPOP00000011443	ENSCPOP00000033093	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Valosin containing protein; Belongs to the AAA ATPase family.	0.429
ATP5F1B	ATP5F1A	ENSCPOP00000016071	ENSCPOP00000011443	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ATP5F1B	PDIA3	ENSCPOP00000016071	ENSCPOP00000007361	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Protein disulfide-isomerase.	0.407
ATP5F1B	VCP	ENSCPOP00000016071	ENSCPOP00000033093	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Valosin containing protein; Belongs to the AAA ATPase family.	0.425
Cd8b	LOC100713317	ENSCPOP00000004923	ENSCPOP00000002116	CD8 beta.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.837
Cd8b	LOC100713873	ENSCPOP00000004923	ENSCPOP00000001179	CD8 beta.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.837
Cd8b	LOC100723960	ENSCPOP00000004923	ENSCPOP00000006900	CD8 beta.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.837
DERL1	TAP1	ENSCPOP00000027392	ENSCPOP00000015900	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Transporter 1, ATP binding cassette subfamily B member.	0.443
DERL1	Tap2	ENSCPOP00000027392	ENSCPOP00000022076	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.443
DERL1	VCP	ENSCPOP00000027392	ENSCPOP00000033093	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.997
LOC100713317	Cd8b	ENSCPOP00000002116	ENSCPOP00000004923	Ig-like domain-containing protein; Belongs to the MHC class I family.	CD8 beta.	0.837
LOC100713317	PDIA3	ENSCPOP00000002116	ENSCPOP00000007361	Ig-like domain-containing protein; Belongs to the MHC class I family.	Protein disulfide-isomerase.	0.841
LOC100713317	TAP1	ENSCPOP00000002116	ENSCPOP00000015900	Ig-like domain-containing protein; Belongs to the MHC class I family.	Transporter 1, ATP binding cassette subfamily B member.	0.637
LOC100713317	Tap2	ENSCPOP00000002116	ENSCPOP00000022076	Ig-like domain-containing protein; Belongs to the MHC class I family.	Uncharacterized protein.	0.581
LOC100713873	Cd8b	ENSCPOP00000001179	ENSCPOP00000004923	Ig-like domain-containing protein; Belongs to the MHC class I family.	CD8 beta.	0.837
LOC100713873	PDIA3	ENSCPOP00000001179	ENSCPOP00000007361	Ig-like domain-containing protein; Belongs to the MHC class I family.	Protein disulfide-isomerase.	0.841
LOC100713873	TAP1	ENSCPOP00000001179	ENSCPOP00000015900	Ig-like domain-containing protein; Belongs to the MHC class I family.	Transporter 1, ATP binding cassette subfamily B member.	0.637
LOC100713873	Tap2	ENSCPOP00000001179	ENSCPOP00000022076	Ig-like domain-containing protein; Belongs to the MHC class I family.	Uncharacterized protein.	0.581
LOC100723960	Cd8b	ENSCPOP00000006900	ENSCPOP00000004923	Ig-like domain-containing protein; Belongs to the MHC class I family.	CD8 beta.	0.837