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Pold3 Pold3 DNA2 DNA2 POLE3 POLE3 Pold4 Pold4 POLE4 POLE4 POLD1 POLD1 REV3L REV3L POLD2 POLD2 MAD2L2 MAD2L2 CRCP CRCP Prim1 Prim1 POLE POLE POLG POLG POLG2 POLG2 POLE2 POLE2 PRIM2 PRIM2 POLA1 POLA1 Pola2 Pola2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pold3Uncharacterized protein. (466 aa)
DNA2DNA replication helicase/nuclease 2. (1021 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
Pold4Uncharacterized protein. (107 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (116 aa)
POLD1DNA polymerase. (1134 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (2940 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
CRCPDNA-directed RNA polymerase III subunit RPC9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity); Belongs to the eukaryotic RPC9 RNA polymerase subunit family. (63 aa)
Prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa)
POLGDNA polymerase gamma, catalytic subunit. (1206 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (482 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
PRIM2DNA primase subunit 2. (432 aa)
POLA1DNA polymerase. (1467 aa)
Pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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