STRINGSTRING
RPA1 RPA1 Pola2 Pola2 POLA1 POLA1 PRIM2 PRIM2 Pold3 Pold3 RPA2 RPA2 SMARCAL1 SMARCAL1 Prim1 Prim1 POLD2 POLD2 PRPF19 PRPF19 POLD1 POLD1 Pold4 Pold4 RPA3 RPA3 TONSL TONSL BCAS2 BCAS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
Pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
POLA1DNA polymerase. (1467 aa)
PRIM2DNA primase subunit 2. (432 aa)
Pold3Uncharacterized protein. (466 aa)
RPA2Replication protein A2. (270 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (938 aa)
Prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
PRPF19Pre-mRNA processing factor 19. (513 aa)
POLD1DNA polymerase. (1134 aa)
Pold4Uncharacterized protein. (107 aa)
RPA3Replication protein A3. (121 aa)
TONSLTonsoku like, DNA repair protein. (1395 aa)
BCAS2BCAS2 pre-mRNA processing factor. (225 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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