42 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRPV2	Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (720 aa)
	Mapt	Microtubule-associated protein. (370 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
	PARD3	Par-3 family cell polarity regulator. (1294 aa)
	BOC	BOC cell adhesion associated, oncogene regulated. (1106 aa)
	OLFM1	Olfactomedin 1. (483 aa)
	KIF5C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
	H0W3X9_CAVPO	Uncharacterized protein. (2048 aa)
	DBN1	Drebrin 1. (677 aa)
	RTN4R	Reticulon 4 receptor. (434 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1137 aa)
	L1CAM	L1 cell adhesion molecule. (1255 aa)
	LOC100725824	HATPase_c domain-containing protein. (695 aa)
	TRAK2	Trafficking kinesin protein 2. (914 aa)
	CYFIP1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1264 aa)
	ENSCPOP00000024297	Uncharacterized protein. (406 aa)
	LRP1	LDL receptor related protein 1. (4508 aa)
	TAOK2	TAO kinase 2. (1241 aa)
	FLRT3	Fibronectin leucine rich transmembrane protein 3. (649 aa)
	COBL	Cordon-bleu WH2 repeat protein. (1253 aa)
	AGRN	Agrin. (1967 aa)
	TRAK1	Trafficking kinesin protein 1. (931 aa)
	LIMK1	LIM domain kinase 1. (646 aa)
	APC	APC regulator of WNT signaling pathway. (2842 aa)
	Hsp90aa1	Heat shock protein 90 alpha family class A member 1. (733 aa)
	DCC	DCC netrin 1 receptor. (991 aa)
	PTCH1	Patched 1. (1379 aa)
	FKBP4	Peptidylprolyl isomerase. (458 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (723 aa)
	DYNLT1	Dynein light chain Tctex-type 1. (113 aa)
	NEO1	Neogenin 1. (1465 aa)
	NIN	Ninein. (2132 aa)
	KIF5B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (929 aa)
	C9orf72	C9orf72-SMCR8 complex subunit. (481 aa)
	PARD6A	Par-6 family cell polarity regulator alpha. (346 aa)
	SHTN1	Shootin 1. (631 aa)
	EPHA4	EPH receptor A4. (986 aa)
	MYO9A	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2603 aa)
	FLNA	Filamin A. (2645 aa)
	ENSCPOP00000027747	LAM_G_DOMAIN domain-containing protein. (151 aa)
	GPM6A	Glycoprotein M6A. (278 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (697 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	ENSCPOP00000024297	ENSCPOP00000026704	ENSCPOP00000024297	Agrin.	Uncharacterized protein.	0.930
AGRN	H0W3X9_CAVPO	ENSCPOP00000026704	ENSCPOP00000017678	Agrin.	Uncharacterized protein.	0.930
AGRN	LRP1	ENSCPOP00000026704	ENSCPOP00000025275	Agrin.	LDL receptor related protein 1.	0.786
APC	ENSCPOP00000024297	ENSCPOP00000001434	ENSCPOP00000024297	APC regulator of WNT signaling pathway.	Uncharacterized protein.	0.433
APC	H0W3X9_CAVPO	ENSCPOP00000001434	ENSCPOP00000017678	APC regulator of WNT signaling pathway.	Uncharacterized protein.	0.433
APC	HDAC5	ENSCPOP00000001434	ENSCPOP00000021346	APC regulator of WNT signaling pathway.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.426
APC	LRP1	ENSCPOP00000001434	ENSCPOP00000025275	APC regulator of WNT signaling pathway.	LDL receptor related protein 1.	0.433
BOC	ENSCPOP00000024297	ENSCPOP00000016225	ENSCPOP00000024297	BOC cell adhesion associated, oncogene regulated.	Uncharacterized protein.	0.909
BOC	FLRT3	ENSCPOP00000016225	ENSCPOP00000026484	BOC cell adhesion associated, oncogene regulated.	Fibronectin leucine rich transmembrane protein 3.	0.640
BOC	H0W3X9_CAVPO	ENSCPOP00000016225	ENSCPOP00000017678	BOC cell adhesion associated, oncogene regulated.	Uncharacterized protein.	0.695
BOC	NEO1	ENSCPOP00000016225	ENSCPOP00000005285	BOC cell adhesion associated, oncogene regulated.	Neogenin 1.	0.423
BOC	PTCH1	ENSCPOP00000016225	ENSCPOP00000002160	BOC cell adhesion associated, oncogene regulated.	Patched 1.	0.970
BOC	SMO	ENSCPOP00000016225	ENSCPOP00000011817	BOC cell adhesion associated, oncogene regulated.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.945
C9orf72	Mapt	ENSCPOP00000008502	ENSCPOP00000011723	C9orf72-SMCR8 complex subunit.	Microtubule-associated protein.	0.609
CYFIP1	EPHA4	ENSCPOP00000024210	ENSCPOP00000009930	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	EPH receptor A4.	0.442
CYFIP1	LIMK1	ENSCPOP00000024210	ENSCPOP00000000664	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	LIM domain kinase 1.	0.515
DCC	MYO9A	ENSCPOP00000001825	ENSCPOP00000027038	DCC netrin 1 receptor.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.425
ENSCPOP00000024297	AGRN	ENSCPOP00000024297	ENSCPOP00000026704	Uncharacterized protein.	Agrin.	0.930
ENSCPOP00000024297	APC	ENSCPOP00000024297	ENSCPOP00000001434	Uncharacterized protein.	APC regulator of WNT signaling pathway.	0.433
ENSCPOP00000024297	BOC	ENSCPOP00000024297	ENSCPOP00000016225	Uncharacterized protein.	BOC cell adhesion associated, oncogene regulated.	0.909