15 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCPOP00000024611	PDZ domain-containing protein. (132 aa)
	ATP2A2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
	ANXA11	Annexin. (499 aa)
	KCNK3	Potassium two pore domain channel subfamily K member 3. (270 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1603 aa)
	S100A11	Protein S100; Belongs to the S-100 family. (99 aa)
	Anxa2	Annexin. (339 aa)
	AGER	Advanced glycosylation end-product specific receptor. (377 aa)
	EZR	Ezrin. (586 aa)
	ENSCPOP00000029877	PDZ domain-containing protein. (147 aa)
	S100A1	Protein S100; Belongs to the S-100 family. (94 aa)
	Cacybp	Uncharacterized protein. (230 aa)
	S100B	Protein S100; Belongs to the S-100 family. (92 aa)
	ENSCPOP00000026288	Uncharacterized protein. (201 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGER	S100A1	ENSCPOP00000000519	ENSCPOP00000027012	Advanced glycosylation end-product specific receptor.	Protein S100; Belongs to the S-100 family.	0.461
AGER	S100A11	ENSCPOP00000000519	ENSCPOP00000008747	Advanced glycosylation end-product specific receptor.	Protein S100; Belongs to the S-100 family.	0.823
AGER	S100B	ENSCPOP00000000519	ENSCPOP00000026644	Advanced glycosylation end-product specific receptor.	Protein S100; Belongs to the S-100 family.	0.993
ANXA11	Anxa2	ENSCPOP00000016843	ENSCPOP00000005768	Annexin.	Annexin.	0.582
ANXA11	ENSCPOP00000024611	ENSCPOP00000016843	ENSCPOP00000024611	Annexin.	PDZ domain-containing protein.	0.502
ANXA11	ENSCPOP00000029877	ENSCPOP00000016843	ENSCPOP00000029877	Annexin.	PDZ domain-containing protein.	0.466
ATP2A2	S100A1	ENSCPOP00000024348	ENSCPOP00000027012	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Protein S100; Belongs to the S-100 family.	0.636
Anxa2	ANXA11	ENSCPOP00000005768	ENSCPOP00000016843	Annexin.	Annexin.	0.582
Anxa2	ENSCPOP00000024611	ENSCPOP00000005768	ENSCPOP00000024611	Annexin.	PDZ domain-containing protein.	0.986
Anxa2	ENSCPOP00000029877	ENSCPOP00000005768	ENSCPOP00000029877	Annexin.	PDZ domain-containing protein.	0.870
Anxa2	EZR	ENSCPOP00000005768	ENSCPOP00000032958	Annexin.	Ezrin.	0.497
Anxa2	S100A1	ENSCPOP00000005768	ENSCPOP00000027012	Annexin.	Protein S100; Belongs to the S-100 family.	0.600
Anxa2	S100A11	ENSCPOP00000005768	ENSCPOP00000008747	Annexin.	Protein S100; Belongs to the S-100 family.	0.958
Cacybp	S100A1	ENSCPOP00000026872	ENSCPOP00000027012	Uncharacterized protein.	Protein S100; Belongs to the S-100 family.	0.439
ENSCPOP00000024611	ANXA11	ENSCPOP00000024611	ENSCPOP00000016843	PDZ domain-containing protein.	Annexin.	0.502
ENSCPOP00000024611	Anxa2	ENSCPOP00000024611	ENSCPOP00000005768	PDZ domain-containing protein.	Annexin.	0.986
ENSCPOP00000024611	ENSCPOP00000029877	ENSCPOP00000024611	ENSCPOP00000029877	PDZ domain-containing protein.	PDZ domain-containing protein.	0.805
ENSCPOP00000024611	EZR	ENSCPOP00000024611	ENSCPOP00000032958	PDZ domain-containing protein.	Ezrin.	0.529
ENSCPOP00000024611	S100A11	ENSCPOP00000024611	ENSCPOP00000008747	PDZ domain-containing protein.	Protein S100; Belongs to the S-100 family.	0.654
ENSCPOP00000026288	S100A1	ENSCPOP00000026288	ENSCPOP00000027012	Uncharacterized protein.	Protein S100; Belongs to the S-100 family.	0.439