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| | GABBR1 | Gamma-aminobutyric acid type B receptor subunit 1. (844 aa) |
| | TBXA2R | Thromboxane A2 receptor. (347 aa) |
| | RPL15 | Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa) |
| | GOT2 | Aspartate aminotransferase. (430 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | RGS19 | Regulator of G protein signaling 19. (216 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (447 aa) |
| | ENSCPOP00000030888 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa) |
| | Chrnb2 | Uncharacterized protein. (499 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | SLC23A2 | Solute carrier family 23 member 2. (650 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (481 aa) |
| | ST6GAL1 | ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (405 aa) |
| | CRH | Corticotropin releasing hormone. (193 aa) |
| | MSTN | Myostatin. (376 aa) |
| | UNC79 | Unc-79 homolog, NALCN channel complex subunit. (2545 aa) |
| | CBL | Cbl proto-oncogene. (894 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (165 aa) |
| | SDF4 | Stromal cell derived factor 4. (378 aa) |
| | ENSCPOP00000029129 | Protein kinase domain-containing protein. (254 aa) |
| | Cdk1 | Protein kinase domain-containing protein. (240 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | H0V5P5_CAVPO | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (385 aa) |
| | Bad | Uncharacterized protein. (166 aa) |
| | ABCB11 | Uncharacterized protein. (1320 aa) |
| | SLC10A1 | Solute carrier family 10 member 1. (285 aa) |
| | ADCYAP1R1 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1381 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) |
| | GRIN3A | Glutamate ionotropic receptor NMDA type subunit 3A. (1114 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (732 aa) |
| | LOC100732008 | PKS_ER domain-containing protein. (375 aa) |
| | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1. (1579 aa) |
| | ALAD | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa) |
| | AACS | Acetoacetyl-CoA synthetase. (672 aa) |
| | GGH | Folate gamma-glutamyl hydrolase. (318 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa) |
| | GATA3 | GATA binding protein 3. (443 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | OGG1 | 8-oxoguanine DNA glycosylase. (303 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa) |
| | GLRA2 | Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (615 aa) |
| | ACTC1 | Actin alpha cardiac muscle 1. (377 aa) |
| | NR0B2 | Nuclear receptor subfamily 0 group B member 2. (258 aa) |
| | TUFM | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (452 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (340 aa) |
| | TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1754 aa) |
| | GLRA3 | Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa) |
| | TH | Tyrosine hydroxylase. (498 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (527 aa) |
| | CCL7 | C-C motif chemokine. (97 aa) |
| | LOC100730761 | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1462 aa) |
| | GLRA1 | Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa) |
| | Chrna7 | Uncharacterized protein. (483 aa) |
| | CA3 | Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (260 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | RARA | Retinoic acid receptor alpha. (462 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (801 aa) |
| | USP46 | Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family. (366 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (247 aa) |
| | CD164 | CD164 molecule. (202 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | RGS4 | Regulator of G protein signaling 4. (205 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (943 aa) |
| | CPT1A | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (772 aa) |
| | ARSA | Arylsulfatase A. (507 aa) |
| | ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | RGS7 | Regulator of G protein signaling 7. (477 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (864 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) |
| | EPS8 | Epidermal growth factor receptor pathway substrate 8. (821 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1188 aa) |
| | ENSCPOP00000022694 | Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (305 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | KCNMB1 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa) |
| | HOXA1 | Homeobox A1. (333 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa) |
| | CSF3 | Colony stimulating factor 3. (209 aa) |
| | ADCYAP1 | Adenylate cyclase activating polypeptide 1. (180 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (837 aa) |
| | GNRH1 | GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. (92 aa) |
| | TYMS | Thymidylate synthetase. (314 aa) |
| | ND4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (474 aa) |
| | OPRM1 | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP- bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell ty [...] (416 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (445 aa) |
| | BCL2 | BCL2 apoptosis regulator. (183 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (903 aa) |
| | DBH | Dopamine beta-hydroxylase. (616 aa) |
| | NPPC | Natriuretic peptide C. (126 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (294 aa) |
| | Vhl | Uncharacterized protein. (182 aa) |
| | CD14 | CD14 molecule. (395 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | CNR1 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa) |
| | SLC6A3 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa) |
| | RGS2 | Regulator of G protein signaling 2. (211 aa) |
| | EEF1B2 | Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family. (225 aa) |
| | ACTR2 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (533 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (214 aa) |
| | PHB | Prohibitin. (272 aa) |
| | SIRT1 | Sirtuin 1. (717 aa) |
| | MAOB | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). (520 aa) |
| | CDO1 | Cysteine dioxygenase. (200 aa) |
| | SETDB1 | SET domain bifurcated histone lysine methyltransferase 1. (1290 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | CRHBP | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1155 aa) |
| | DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | CYP7A1 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa) |
| | KCNC2 | Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (418 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa) |
| | ADIPOR2 | Adiponectin receptor 2. (386 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
