54 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	B3GALT2	Hexosyltransferase. (422 aa)
	ST6GALNAC3	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (305 aa)
	CYP4F22	Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (547 aa)
	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (375 aa)
	B4GALT6	Beta-1,4-galactosyltransferase 6. (382 aa)
	ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (323 aa)
	AGK	Acylglycerol kinase. (421 aa)
	FA2H	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
	SPTLC1	Serine palmitoyltransferase long chain base subunit 1. (461 aa)
	SGMS1	Sphingomyelin synthase 1. (413 aa)
	ASAH2	Neutral ceramidase. (752 aa)
	ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (398 aa)
	B4GALT5	Beta-1,4-galactosyltransferase 5. (349 aa)
	ALOXE3	Arachidonate lipoxygenase 3. (711 aa)
	P2RX1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (339 aa)
	ENSCPOP00000026943	TLC domain-containing protein. (287 aa)
	SMPD4	Sphingomyelin phosphodiesterase 4. (823 aa)
	B3GALT1	Hexosyltransferase. (326 aa)
	B4GALT3	Beta-1,4-galactosyltransferase 3. (396 aa)
	SPTSSA	Serine palmitoyltransferase small subunit A. (71 aa)
	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (350 aa)
	SGMS2	Sphingomyelin synthase 2. (365 aa)
	ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (359 aa)
	ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (335 aa)
	Gdf1	TGF_BETA_2 domain-containing protein. (367 aa)
	ALOX12B	Arachidonate 12-lipoxygenase, 12R type. (700 aa)
	ENSCPOP00000024878	Uncharacterized protein. (110 aa)
	SAMD8	Sterile alpha motif domain containing 8. (415 aa)
	St6galnac6	Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (332 aa)
	SPTSSB	Serine palmitoyltransferase small subunit B. (76 aa)
	CERS5	Ceramide synthase 5. (428 aa)
	SPTLC2	Serine palmitoyltransferase long chain base subunit 2. (562 aa)
	CERS2	Ceramide synthase 2. (380 aa)
	SMPD1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
	SMPD2	Sphingomyelin phosphodiesterase 2. (430 aa)
	GBA	Glucosylceramidase. (516 aa)
	B4GALNT1	Beta-1,4 N-acetylgalactosaminyltransferase. (533 aa)
	B4GALT4	Beta-1,4-galactosyltransferase 4. (347 aa)
	PNPLA1	Patatin like phospholipase domain containing 1. (554 aa)
	TLCD3B	TLC domain containing 3B. (275 aa)
	ELOVL1	Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (313 aa)
	ASAH1	N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa)
	DEGS1	Delta 4-desaturase, sphingolipid 1. (323 aa)
	UGCG	UDP-glucose ceramide glucosyltransferase. (393 aa)
	TMEM130	Transmembrane protein 130. (345 aa)
	ST6GALNAC5	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (329 aa)
	UGT8	UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (541 aa)
	DEGS2	Delta 4-desaturase, sphingolipid 2. (315 aa)
	CERS4	Ceramide synthase 4. (391 aa)
	ST6GALNAC4	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (302 aa)
	B3GALT4	Hexosyltransferase. (416 aa)
	GAL3ST1	Galactose-3-O-sulfotransferase 1. (423 aa)
	CERS6	Ceramide synthase 6. (392 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGK	ASAH1	ENSCPOP00000013928	ENSCPOP00000007092	Acylglycerol kinase.	N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.	0.427
AGK	ASAH2	ENSCPOP00000013928	ENSCPOP00000013500	Acylglycerol kinase.	Neutral ceramidase.	0.640
AGK	CERS2	ENSCPOP00000013928	ENSCPOP00000001477	Acylglycerol kinase.	Ceramide synthase 2.	0.433
AGK	CERS4	ENSCPOP00000013928	ENSCPOP00000017180	Acylglycerol kinase.	Ceramide synthase 4.	0.433
AGK	CERS5	ENSCPOP00000013928	ENSCPOP00000000369	Acylglycerol kinase.	Ceramide synthase 5.	0.434
AGK	CERS6	ENSCPOP00000013928	ENSCPOP00000020563	Acylglycerol kinase.	Ceramide synthase 6.	0.434
AGK	DEGS1	ENSCPOP00000013928	ENSCPOP00000007806	Acylglycerol kinase.	Delta 4-desaturase, sphingolipid 1.	0.545
AGK	DEGS2	ENSCPOP00000013928	ENSCPOP00000020203	Acylglycerol kinase.	Delta 4-desaturase, sphingolipid 2.	0.545
AGK	ENSCPOP00000026943	ENSCPOP00000013928	ENSCPOP00000026943	Acylglycerol kinase.	TLC domain-containing protein.	0.433
AGK	GBA	ENSCPOP00000013928	ENSCPOP00000002873	Acylglycerol kinase.	Glucosylceramidase.	0.523
AGK	SAMD8	ENSCPOP00000013928	ENSCPOP00000025792	Acylglycerol kinase.	Sterile alpha motif domain containing 8.	0.449
AGK	SGMS1	ENSCPOP00000013928	ENSCPOP00000013503	Acylglycerol kinase.	Sphingomyelin synthase 1.	0.449
AGK	SGMS2	ENSCPOP00000013928	ENSCPOP00000028011	Acylglycerol kinase.	Sphingomyelin synthase 2.	0.449
AGK	SMPD1	ENSCPOP00000013928	ENSCPOP00000001978	Acylglycerol kinase.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.546
AGK	SMPD2	ENSCPOP00000013928	ENSCPOP00000002808	Acylglycerol kinase.	Sphingomyelin phosphodiesterase 2.	0.601
AGK	SMPD4	ENSCPOP00000013928	ENSCPOP00000029621	Acylglycerol kinase.	Sphingomyelin phosphodiesterase 4.	0.538
AGK	TMEM130	ENSCPOP00000013928	ENSCPOP00000009575	Acylglycerol kinase.	Transmembrane protein 130.	0.489
AGK	UGCG	ENSCPOP00000013928	ENSCPOP00000008243	Acylglycerol kinase.	UDP-glucose ceramide glucosyltransferase.	0.410
ALOX12B	CYP4F22	ENSCPOP00000011607	ENSCPOP00000023584	Arachidonate 12-lipoxygenase, 12R type.	Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.	0.829
ALOX12B	PNPLA1	ENSCPOP00000011607	ENSCPOP00000003539	Arachidonate 12-lipoxygenase, 12R type.	Patatin like phospholipase domain containing 1.	0.421