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NEU3 NEU3 GBA2 GBA2 GLA GLA CEL CEL GBA GBA HEXB HEXB NEU4 NEU4 ASAH1 ASAH1 NEU2 NEU2 GALC GALC TMEM130 TMEM130 Hexa Hexa NEU1 NEU1 ASAH2 ASAH2 ACER1 ACER1 GBA3 GBA3 NAGA NAGA ENSCPOP00000022694 ENSCPOP00000022694 GM2A GM2A ACER2 ACER2 ACER3 ACER3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEU3Neuraminidase 3. (415 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (908 aa)
GLAAlpha-galactosidase. (428 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (594 aa)
GBAGlucosylceramidase. (516 aa)
HEXBHexosaminidase subunit beta. (442 aa)
NEU4Neuraminidase 4. (457 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa)
NEU2Neuraminidase 2. (381 aa)
GALCGalactosylceramidase. (685 aa)
TMEM130Transmembrane protein 130. (345 aa)
HexaBeta-hexosaminidase. (527 aa)
NEU1Neuraminidase 1. (404 aa)
ASAH2Neutral ceramidase. (752 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (268 aa)
GBA3Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...] (399 aa)
NAGAAlpha-galactosidase. (413 aa)
ENSCPOP00000022694Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (305 aa)
GM2AGM2 ganglioside activator. (166 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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