35 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOCS1	Suppressor of cytokine signaling 1. (217 aa)
	MSTN	Myostatin. (376 aa)
	PID1	Phosphotyrosine interaction domain containing 1. (217 aa)
	PTPRE	Receptor-type tyrosine-protein phosphatase. (723 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
	INPPL1	Inositol polyphosphate phosphatase like 1. (1267 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1311 aa)
	KANK1	KN motif and ankyrin repeat domains 1. (1353 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	NCOA5	Nuclear receptor coactivator 5. (578 aa)
	GSK3A	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (470 aa)
	TNS2	Tensin 2. (1396 aa)
	SOCS3	Suppressor of cytokine signaling 3. (228 aa)
	TRIM72	Tripartite motif containing 72. (477 aa)
	NUCB2	Nucleobindin 2. (420 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (549 aa)
	PIP4K2C	Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (419 aa)
	ENPP1	Ectonucleotide pyrophosphatase/phosphodiesterase 1. (900 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa)
	YBX1	YB1. (324 aa)
	PTPRF	Protein tyrosine phosphatase receptor type F. (1908 aa)
	GRB10	Growth factor receptor bound protein 10. (616 aa)
	PIP4K2A	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (364 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (461 aa)
	PIP4K2B	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (362 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (559 aa)
	SLC27A4	Solute carrier family 27 member 4. (642 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa)
	H0V0H5_CAVPO	ANK_REP_REGION domain-containing protein. (1480 aa)
	TSC2	TSC complex subunit 2. (1745 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
	GRB14	Growth factor receptor bound protein 14. (509 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB10	PTPN2	ENSCPOP00000008282	ENSCPOP00000006301	Growth factor receptor bound protein 10.	Tyrosine-protein phosphatase non-receptor type.	0.484
GRB10	PTPRE	ENSCPOP00000008282	ENSCPOP00000028207	Growth factor receptor bound protein 10.	Receptor-type tyrosine-protein phosphatase.	0.477
GRB10	PTPRF	ENSCPOP00000008282	ENSCPOP00000009285	Growth factor receptor bound protein 10.	Protein tyrosine phosphatase receptor type F.	0.477
GRB10	PTPRJ	ENSCPOP00000008282	ENSCPOP00000024812	Growth factor receptor bound protein 10.	Protein tyrosine phosphatase receptor type J.	0.471
GRB14	PTPN2	ENSCPOP00000000761	ENSCPOP00000006301	Growth factor receptor bound protein 14.	Tyrosine-protein phosphatase non-receptor type.	0.484
GRB14	PTPRE	ENSCPOP00000000761	ENSCPOP00000028207	Growth factor receptor bound protein 14.	Receptor-type tyrosine-protein phosphatase.	0.477
GRB14	PTPRF	ENSCPOP00000000761	ENSCPOP00000009285	Growth factor receptor bound protein 14.	Protein tyrosine phosphatase receptor type F.	0.477
GRB14	PTPRJ	ENSCPOP00000000761	ENSCPOP00000024812	Growth factor receptor bound protein 14.	Protein tyrosine phosphatase receptor type J.	0.471
GSK3A	INPPL1	ENSCPOP00000019863	ENSCPOP00000025833	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.	Inositol polyphosphate phosphatase like 1.	0.521
GSK3A	NCK1	ENSCPOP00000019863	ENSCPOP00000022728	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.	Cytoplasmic protein.	0.419
GSK3A	PRKAA1	ENSCPOP00000019863	ENSCPOP00000004902	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.456
GSK3A	TSC2	ENSCPOP00000019863	ENSCPOP00000002913	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.	TSC complex subunit 2.	0.853
H0V0H5_CAVPO	NCK1	ENSCPOP00000002964	ENSCPOP00000022728	ANK_REP_REGION domain-containing protein.	Cytoplasmic protein.	0.404
IL1B	RELA	ENSCPOP00000001784	ENSCPOP00000016204	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	RELA proto-oncogene, NF-kB subunit.	0.966
IL1B	SOCS3	ENSCPOP00000001784	ENSCPOP00000017841	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Suppressor of cytokine signaling 3.	0.732
INPP5K	INPPL1	ENSCPOP00000006203	ENSCPOP00000025833	Inositol polyphosphate-5-phosphatase K.	Inositol polyphosphate phosphatase like 1.	0.436
INPP5K	PIP4K2A	ENSCPOP00000006203	ENSCPOP00000006815	Inositol polyphosphate-5-phosphatase K.	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.	0.402
INPP5K	PIP4K2B	ENSCPOP00000006203	ENSCPOP00000004926	Inositol polyphosphate-5-phosphatase K.	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.	0.402
INPP5K	PIP4K2C	ENSCPOP00000006203	ENSCPOP00000014303	Inositol polyphosphate-5-phosphatase K.	Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.	0.402
INPP5K	TNS2	ENSCPOP00000006203	ENSCPOP00000019845	Inositol polyphosphate-5-phosphatase K.	Tensin 2.	0.639