STRINGSTRING
CTSB CTSB MEN1 MEN1 PTGS2 PTGS2 CITED2 CITED2 ASH1L ASH1L EPOR EPOR PTN PTN CTSV CTSV TPPP3 TPPP3 PPARD PPARD CDH1 CDH1 MAPK1 MAPK1 GHSR GHSR JUNB JUNB CYP27B1 CYP27B1 BSG BSG GHRL GHRL PLA2G4A PLA2G4A NDP NDP DEDD DEDD TCF23 TCF23 MAPK3 MAPK3 LIF LIF PTGIS PTGIS STC1 STC1 VDR VDR GJB2 GJB2 KISS1 KISS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTSBCathepsin B; Belongs to the peptidase C1 family. (340 aa)
MEN1Menin 1. (615 aa)
PTGS2Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (604 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
ASH1LASH1 like histone lysine methyltransferase. (2942 aa)
EPORErythropoietin receptor. (540 aa)
PTNPleiotrophin. (168 aa)
CTSVCathepsin V; Belongs to the peptidase C1 family. (333 aa)
TPPP3Tubulin polymerization promoting protein family member 3. (176 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (891 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (302 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa)
BSGBasigin (Ok blood group). (384 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
PLA2G4APhospholipase A2. (749 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
DEDDDeath effector domain containing. (318 aa)
TCF23Transcription factor 23. (210 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (475 aa)
STC1Stanniocalcin 1. (247 aa)
VDRVitamin D receptor. (424 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
KISS1KiSS-1 metastasis suppressor. (128 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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