STRINGSTRING
EIF2S1 EIF2S1 CSNK1G1 CSNK1G1 FGFR2 FGFR2 LMTK2 LMTK2 ENSCPOP00000027605 ENSCPOP00000027605 NLK NLK ULK1 ULK1 MAP4K1 MAP4K1 Mknk1 Mknk1 ATG13 ATG13 HTATIP2 HTATIP2 MINK1 MINK1 MAP3K11 MAP3K11 PTK2B PTK2B Camk2d Camk2d EPHB4 EPHB4 DAPK3 DAPK3 MAP3K13 MAP3K13 MYO3B MYO3B BTK BTK MYLK2 MYLK2 STK17B STK17B CAMKK2 CAMKK2 IGF1R IGF1R IRAK3 IRAK3 WNK3 WNK3 H0V4A5_CAVPO H0V4A5_CAVPO PRKD1 PRKD1 ZAP70 ZAP70 AAK1 AAK1 STK16 STK16 UHMK1 UHMK1 FER FER Ulk3 Ulk3 PRKD2 PRKD2 NTRK1 NTRK1 INSRR INSRR CLK4 CLK4 STK26 STK26 HSPA9 HSPA9 EPHB1 EPHB1 VRK1 VRK1 MAK MAK BRD4 BRD4 ACVR1B ACVR1B FGFR4 FGFR4 MAP3K3 MAP3K3 STK4 STK4 IRAK1 IRAK1 ATP13A2 ATP13A2 CDK5 CDK5 ENSCPOP00000032677 ENSCPOP00000032677 Prkaca Prkaca CLK2 CLK2 AATK AATK EGFR EGFR PAK1 PAK1 ERN1 ERN1 PTK2 PTK2 MAP3K12 MAP3K12 H0VMR0_CAVPO H0VMR0_CAVPO GRK7 GRK7 MAPK15 MAPK15 FLT1 FLT1 SIK2 SIK2 GRK1 GRK1 MET MET STK39 STK39 EIF2AK3 EIF2AK3 H0VPD8_CAVPO H0VPD8_CAVPO GSK3B GSK3B TXK TXK MELK MELK JAK2 JAK2 EIF2AK1 EIF2AK1 MKNK2 MKNK2 TRPM7 TRPM7 Csnk2a1 Csnk2a1 Trim28 Trim28 STK33 STK33 PDGFRB PDGFRB HK1 HK1 PIM2 PIM2 CHEK2 CHEK2 PASK PASK PEAK1 PEAK1 STK10 STK10 FGFR1 FGFR1 CAMK2A CAMK2A PTK6 PTK6 SRMS SRMS ATR ATR CAMK4 CAMK4 FLT3 FLT3 CDKL5 CDKL5 GRK5 GRK5 CSNK1G3 CSNK1G3 LCK LCK NEK6 NEK6 HCK HCK FLT4 FLT4 ALK ALK OXSR1 OXSR1 MAPKAPK5 MAPKAPK5 TNK1 TNK1 DDR2 DDR2 TEK TEK TYRO3 TYRO3 KDR KDR ULK2 ULK2 DYRK1B DYRK1B SYK SYK RIOK2 RIOK2 TSSK4 TSSK4 ATM ATM EPHA4 EPHA4 ERBB4 ERBB4 NEK2 NEK2 TRIM24 TRIM24 KIT KIT MTOR MTOR LYN LYN PDGFRA PDGFRA EEF2K EEF2K TNIK TNIK TAOK1 TAOK1 EIF2AK2 EIF2AK2 THY1 THY1 SMG1 SMG1 STK17A STK17A TGFBR1 TGFBR1 PRKG2 PRKG2 MAP3K1 MAP3K1 BMX BMX FGR FGR PIM3 PIM3 ATG101 ATG101 VRK2 VRK2 YES1 YES1 PINK1 PINK1 MAP2K2 MAP2K2 CSF1R CSF1R PIM1 PIM1 BCR BCR CLK1 CLK1 Sik1 Sik1 MAPKAPK2 MAPKAPK2 MOS MOS CAMK2B CAMK2B RB1CC1 RB1CC1 CLK3 CLK3 TAOK3 TAOK3 RIPK3 RIPK3 HIPK4 HIPK4 EPHB3 EPHB3 DAPK1 DAPK1 EPHA8 EPHA8 INSR INSR Fes Fes MAPK7 MAPK7 STK25 STK25 CSNK1G2 CSNK1G2 SLK SLK H0WDX0_CAVPO H0WDX0_CAVPO DAPK2 DAPK2 SRC SRC NTRK2 NTRK2 MAPKAPK3 MAPKAPK3 DDR1 DDR1 FAM20C FAM20C DYRK1A DYRK1A RIPK1 RIPK1 WNK2 WNK2 MAPK14 MAPK14 PAK2 PAK2 MUSK MUSK CAMK2G CAMK2G CSK CSK STK24 STK24 PIKFYVE PIKFYVE PRKCG PRKCG EPHA1 EPHA1 PHKA1 PHKA1 CAD CAD FYN FYN STK11 STK11 PRKCD PRKCD FGFR3 FGFR3 EIF2AK4 EIF2AK4 WNK1 WNK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (459 aa)
FGFR2Fibroblast growth factor receptor. (801 aa)
LMTK2Lemur tyrosine kinase 2. (1493 aa)
ENSCPOP00000027605Uncharacterized protein. (157 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1037 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
Mknk1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (421 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
HTATIP2HIV-1 Tat interactive protein 2. (242 aa)
MINK1Misshapen like kinase 1. (1342 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (850 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
Camk2dProtein kinase domain-containing protein. (532 aa)
EPHB4EPH receptor B4. (1280 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (950 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1306 aa)
BTKTyrosine-protein kinase. (659 aa)
MYLK2Myosin light chain kinase 2. (593 aa)
STK17BSerine/threonine kinase 17b; Belongs to the protein kinase superfamily. (372 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (565 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (576 aa)
WNK3WNK lysine deficient protein kinase 3. (1746 aa)
H0V4A5_CAVPOUncharacterized protein. (830 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (845 aa)
ZAP70Tyrosine-protein kinase. (551 aa)
AAK1AP2 associated kinase 1. (957 aa)
STK16Serine/threonine kinase 16. (305 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
Ulk3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (474 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (865 aa)
NTRK1Tyrosine-protein kinase receptor. (798 aa)
INSRRInsulin receptor-related protein alpha chain; Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB (By similarity). (1300 aa)
CLK4CDC like kinase 4; Belongs to the protein kinase superfamily. (481 aa)
STK26Serine/threonine kinase 26. (410 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (678 aa)
EPHB1EPH receptor B1. (736 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
MAKMale germ cell associated kinase. (622 aa)
BRD4Bromodomain containing 4. (1373 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
STK4Serine/threonine kinase 4. (487 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (707 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1173 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSCPOP00000032677Eph LBD domain-containing protein. (286 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
CLK2CDC like kinase 2; Belongs to the protein kinase superfamily. (500 aa)
AATKApoptosis associated tyrosine kinase. (1313 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (974 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa)
H0VMR0_CAVPOTyrosine-protein kinase receptor. (625 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (550 aa)
MAPK15Mitogen-activated protein kinase. (539 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1332 aa)
SIK2Salt inducible kinase 2. (883 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1380 aa)
STK39Serine/threonine kinase 39. (474 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1112 aa)
H0VPD8_CAVPOUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (749 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
TXKTyrosine-protein kinase. (507 aa)
MELKNon-specific serine/threonine protein kinase. (643 aa)
JAK2Tyrosine-protein kinase. (1035 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (574 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1754 aa)
Csnk2a1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
Trim28Uncharacterized protein. (829 aa)
STK33Serine/threonine kinase 33; Belongs to the protein kinase superfamily. (461 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa)
HK1Hexokinase 1. (919 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (370 aa)
CHEK2Checkpoint kinase 2. (546 aa)
PASKPAS domain containing serine/threonine kinase. (1342 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1738 aa)
STK10Serine/threonine kinase 10. (959 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PTK6Tyrosine-protein kinase. (451 aa)
SRMSTyrosine-protein kinase. (508 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2539 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (418 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (987 aa)
CDKL5Cyclin dependent kinase like 5. (947 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (448 aa)
LCKTyrosine-protein kinase. (511 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (313 aa)
HCKTyrosine-protein kinase. (503 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1343 aa)
ALKTyrosine-protein kinase receptor. (1350 aa)
OXSR1Oxidative stress responsive kinase 1. (526 aa)
MAPKAPK5MAPK activated protein kinase 5. (474 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (668 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (854 aa)
TEKTEK receptor tyrosine kinase. (1029 aa)
TYRO3TYRO3 protein tyrosine kinase. (880 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1033 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (680 aa)
SYKTyrosine-protein kinase. (579 aa)
RIOK2RIO kinase 2. (548 aa)
TSSK4Testis specific serine kinase 4. (296 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3031 aa)
EPHA4EPH receptor A4. (986 aa)
ERBB4Receptor protein-tyrosine kinase. (1263 aa)
NEK2NIMA related kinase 2. (442 aa)
TRIM24Tripartite motif containing 24. (1002 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
LYNTyrosine-protein kinase. (512 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
EEF2KEukaryotic elongation factor 2 kinase. (724 aa)
TNIKTRAF2 and NCK interacting kinase. (1360 aa)
TAOK1TAO kinase 1. (963 aa)
EIF2AK2Interferon-induced double-stranded RNA-activated protein kinase. (519 aa)
THY1Thy-1 protein. (161 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3632 aa)
STK17ASerine/threonine kinase 17a. (377 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
PRKG2cGMP-dependent protein kinase. (758 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1370 aa)
BMXTyrosine-protein kinase. (655 aa)
FGRTyrosine-protein kinase. (527 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (326 aa)
ATG101Autophagy related 101. (218 aa)
VRK2VRK serine/threonine kinase 2. (508 aa)
YES1Tyrosine-protein kinase. (541 aa)
PINK1PTEN induced kinase 1. (574 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (979 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
BCRBCR activator of RhoGEF and GTPase. (1227 aa)
CLK1CDC like kinase 1; Belongs to the protein kinase superfamily. (484 aa)
Sik1Uncharacterized protein. (777 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (357 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (659 aa)
RB1CC1RB1 inducible coiled-coil 1. (1431 aa)
CLK3CDC like kinase 3. (601 aa)
TAOK3TAO kinase 3. (899 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (482 aa)
HIPK4Homeodomain interacting protein kinase 4. (616 aa)
EPHB3EPH receptor B3. (1011 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
EPHA8EPH receptor A8. (990 aa)
INSRTyrosine-protein kinase receptor. (1371 aa)
FesF-BAR domain-containing protein. (95 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (797 aa)
STK25Serine/threonine kinase 25. (426 aa)
CSNK1G2Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (436 aa)
SLKSTE20-like serine/threonine-protein kinase; Mediates apoptosis and actin stress fiber dissolution. (1231 aa)
H0WDX0_CAVPOProtein kinase domain-containing protein. (809 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (483 aa)
SRCTyrosine-protein kinase. (542 aa)
NTRK2Tyrosine-protein kinase receptor. (816 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (380 aa)
DDR1Tyrosine-protein kinase receptor. (915 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (508 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (664 aa)
WNK2WNK lysine deficient protein kinase 2. (2111 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
MUSKMuscle associated receptor tyrosine kinase. (879 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (545 aa)
CSKTyrosine-protein kinase. (450 aa)
STK24Serine/threonine kinase 24. (470 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2079 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
EPHA1EPH receptor A1. (979 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1237 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2248 aa)
FYNTyrosine-protein kinase. (537 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (435 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
FGFR3Fibroblast growth factor receptor. (801 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1651 aa)
WNK1WNK lysine deficient protein kinase 1. (2528 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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