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| | ABHD6 | Abhydrolase domain containing 6. (337 aa) |
| | ORMDL3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | LOC100717473 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa) |
| | CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1. (125 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | IGFBP7 | Insulin like growth factor binding protein 7. (296 aa) |
| | PEX2 | Peroxisomal biogenesis factor 2. (304 aa) |
| | Snai2 | Uncharacterized protein. (268 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (350 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (967 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa) |
| | Dab2 | PID domain-containing protein. (766 aa) |
| | CLCN2 | Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport (By similarity). Involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (By similarity); Belongs [...] (889 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1. (383 aa) |
| | CGA | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (120 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (590 aa) |
| | ACADL | Acyl-CoA dehydrogenase long chain. (432 aa) |
| | CCN1 | Cellular communication network factor 1. (381 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (740 aa) |
| | MLXIPL | MLX interacting protein like. (854 aa) |
| | H0VUM1_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (146 aa) |
| | MID1IP1 | MID1 interacting protein 1. (144 aa) |
| | BSCL2 | BSCL2 lipid droplet biogenesis associated, seipin. (366 aa) |
| | ACADVL | Acyl-CoA dehydrogenase very long chain. (633 aa) |
| | H0VW66_CAVPO | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa) |
| | CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (700 aa) |
| | DDX20 | DEAD-box helicase 20. (820 aa) |
| | ENSCPOP00000026343 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (214 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (208 aa) |
| | Dbi | ACB domain-containing protein. (87 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity [...] (480 aa) |
| | Rdh10 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa) |
| | SIRT1 | Sirtuin 1. (717 aa) |
| | Pde8b | Phosphodiesterase. (785 aa) |
| | Sik1 | Uncharacterized protein. (777 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | LOC100718644 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (207 aa) |
| | H0W0U4_CAVPO | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (420 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa) |
| | PPARA | Peroxisome proliferator-activated receptor alpha; Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn- glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and [...] (467 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (839 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (678 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (604 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (484 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (521 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (477 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (741 aa) |
| | SCAP | SREBF chaperone. (1260 aa) |
| | C3 | Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. (912 aa) |
| | GIP | Gastric inhibitory polypeptide. (145 aa) |
| | ARMC5 | Armadillo repeat containing 5. (905 aa) |
| | SF1 | Splicing factor 1. (636 aa) |
| | SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (257 aa) |
| | APOC2 | Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. (100 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (231 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1149 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (2080 aa) |
| | ENSCPOP00000027789 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (122 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (246 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | ORMDL1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (165 aa) |
| | LPCAT1 | Lysophosphatidylcholine acyltransferase 1. (486 aa) |
| | DGKQ | Diacylglycerol kinase. (947 aa) |
| | ENSCPOP00000029800 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (179 aa) |
| | HTR2C | 5-hydroxytryptamine receptor 2C. (458 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (418 aa) |
| | LOC100721835 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (458 aa) |
| | ABCA3 | ATP binding cassette subfamily A member 3. (1704 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (720 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (656 aa) |
| | LRRN4CL | LRRN4 C-terminal like. (226 aa) |
| | LOC100725073 | PID domain-containing protein. (745 aa) |
| | CREBL2 | cAMP responsive element binding protein like 2. (120 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (190 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | RAB38 | RAB38, member RAS oncogene family. (211 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (470 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (463 aa) |
| | LOC100730472 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (801 aa) |
| | LOC100720852 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (181 aa) |
| | APOC1 | Apolipoprotein C1. (95 aa) |
| | Ceacam1 | Uncharacterized protein. (518 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (535 aa) |
| | H0WC94_CAVPO | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (770 aa) |
| | CTDNEP1 | CTD nuclear envelope phosphatase 1. (210 aa) |
| | ENSCPOP00000022046 | Thiolase_N domain-containing protein. (103 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (796 aa) |
| | PLA2G6 | Phospholipase A2 group VI. (803 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | FITM2 | Fat storage inducing transmembrane protein 2. (262 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | LDLR | Low density lipoprotein receptor. (807 aa) |
| | PLA2G3 | Phospholipase A2 group III. (645 aa) |
| | THRSP | Thyroid hormone responsive. (145 aa) |
| | SEC14L4 | SEC14 like lipid binding 4. (406 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (525 aa) |
| | LPIN1 | Lipin 1. (899 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa) |
| | Brca1 | Uncharacterized protein. (79 aa) |
| | RGN | Regucalcin. (299 aa) |
| | H0VQ66_CAVPO | Uncharacterized protein. (336 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | APOA5 | Apolipoprotein A5. (429 aa) |
| | ABCA2 | ATP binding cassette subfamily A member 2. (2427 aa) |
| | BMP6 | Bone morphogenetic protein 6. (505 aa) |
| | SEC14L2 | Uncharacterized protein. (403 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | Ces1d | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1263 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (370 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (723 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (420 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | SPHK1 | Sphingosine kinase 1. (386 aa) |
| | AVIL | Advillin. (770 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (248 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (611 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (666 aa) |
| | FDPS | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (352 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (686 aa) |
| | Lhcgr | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (691 aa) |
| | H0VU94_CAVPO | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa) |
| | TREX1 | Three prime repair exonuclease 1. (314 aa) |
| | NR3C1 | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (772 aa) |
| | PDK4 | Protein-serine/threonine kinase. (412 aa) |
| | DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1155 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (933 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | CYP7A1 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | APOB | Apolipoprotein B. (4479 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | DGAT1 | O-acyltransferase. (493 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (308 aa) |
| | ACSL5 | AMP-binding domain-containing protein. (682 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (347 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (765 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (298 aa) |
| | FSHB | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (130 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | Insig2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1048 aa) |
| | HSD17B13 | Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa) |
| | FABP5 | E-FABP; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | SAMD8 | Sterile alpha motif domain containing 8. (415 aa) |
| | SPHK2 | Sphingosine kinase 2. (655 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (532 aa) |
| | CD74 | CD74 molecule. (280 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa) |
| | LOC106026223 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (181 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (443 aa) |
| | PC | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1219 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | ENSCPOP00000024929 | SCP2 domain-containing protein. (143 aa) |
| | ENSCPOP00000024925 | COesterase domain-containing protein. (295 aa) |
| | CHP1 | Calcineurin like EF-hand protein 1. (195 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (356 aa) |
| | ERLIN2 | ER lipid raft associated 2. (339 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (221 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa) |
