STRINGSTRING
ABAT ABAT PLCD1 PLCD1 OXT OXT SLC18A1 SLC18A1 HTR6 HTR6 SYT1 SYT1 DRD3 DRD3 Sdhd Sdhd SYT2 SYT2 STX1A STX1A ENTPD1 ENTPD1 SYT9 SYT9 SYT11 SYT11 H0V5P5_CAVPO H0V5P5_CAVPO GRM2 GRM2 SYT10 SYT10 PTGS1 PTGS1 SYT13 SYT13 SYT5 SYT5 DRD2 DRD2 DTNBP1 DTNBP1 CHRNA6 CHRNA6 SYT4 SYT4 CHRNA4 CHRNA4 LOC100730761 LOC100730761 GHSR GHSR CHGA CHGA PINK1 PINK1 SNCG SNCG SYT3 SYT3 SYT12 SYT12 CNR1 CNR1 CARTPT CARTPT AGT AGT SYT8 SYT8 GABBR1 GABBR1 CXCL12 CXCL12 ADORA2B ADORA2B MYO5A MYO5A Rtn4 Rtn4 SNCA SNCA PTGER3 PTGER3 SYT6 SYT6 ADORA3 ADORA3 P2ry12 P2ry12 KCNA2 KCNA2 KCNB1 KCNB1 OXTR OXTR RAB3A RAB3A PCP4 PCP4 Chrna7 Chrna7 CRHR2 CRHR2 GCK GCK CRH CRH Chrnb2 Chrnb2 SYT17 SYT17 SYT7 SYT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
PLCD1Phosphoinositide phospholipase C. (755 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (437 aa)
SYT1Synaptotagmin 1. (422 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (364 aa)
SdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
SYT2Synaptotagmin 2. (421 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (511 aa)
SYT9Synaptotagmin 9. (487 aa)
SYT11Synaptotagmin 11. (431 aa)
H0V5P5_CAVPOUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (385 aa)
GRM2Glutamate metabotropic receptor 2. (871 aa)
SYT10Synaptotagmin 10. (521 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (553 aa)
SYT13Synaptotagmin 13. (373 aa)
SYT5Synaptotagmin 5. (386 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
DTNBP1Dystrobrevin binding protein 1. (354 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
SYT4Synaptotagmin 4. (425 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (620 aa)
LOC100730761Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (302 aa)
CHGAChromogranin A. (421 aa)
PINK1PTEN induced kinase 1. (574 aa)
SNCGGamma-synuclein; Belongs to the synuclein family. (102 aa)
SYT3Synaptotagmin 3. (587 aa)
SYT12Synaptotagmin 12. (421 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
CARTPTCART prepropeptide. (129 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
SYT8Synaptotagmin 8. (398 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (844 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (221 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
Rtn4Reticulon. (350 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
PTGER3Prostaglandin E receptor 3. (363 aa)
SYT6Synaptotagmin 6. (512 aa)
ADORA3Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (323 aa)
P2ry12Uncharacterized protein. (114 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (390 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
PCP4Purkinje cell protein 4. (62 aa)
Chrna7Uncharacterized protein. (483 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa)
GCKPhosphotransferase. (414 aa)
CRHCorticotropin releasing hormone. (193 aa)
Chrnb2Uncharacterized protein. (499 aa)
SYT17Synaptotagmin 17. (474 aa)
SYT7Synaptotagmin 7. (556 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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