STRINGSTRING
Pitx2 Pitx2 HIF1A HIF1A H0V4A5_CAVPO H0V4A5_CAVPO EDNRA EDNRA NOLC1 NOLC1 EOMES EOMES NOS3 NOS3 SEMA3G SEMA3G DICER1 DICER1 ZEB2 ZEB2 BMP5 BMP5 CTNNB1 CTNNB1 SPRY1 SPRY1 WT1 WT1 WNT4 WNT4 ACTG2 ACTG2 HAND2 HAND2 PHACTR4 PHACTR4 JAG1 JAG1 PPP3R1 PPP3R1 SEMA4D SEMA4D YAP1 YAP1 CDC42 CDC42 SFRP2 SFRP2 SHH SHH SMAD3 SMAD3 MSX1 MSX1 SEMA6B SEMA6B BMP2 BMP2 OVOL2 OVOL2 PTK7 PTK7 MSX2 MSX2 SEMA6C SEMA6C PWWP2A PWWP2A BMPR2 BMPR2 EDN1 EDN1 BMP7 BMP7 SEMA6A SEMA6A EFNB1 EFNB1 EDN3 EDN3 EFNA1 EFNA1 TEAD2 TEAD2 WNT16 WNT16 LRP6 LRP6 KITLG KITLG HEY1 HEY1 SIX1 SIX1 CDH2 CDH2 FLNA FLNA FGFR2 FGFR2 GATA5 GATA5 SFRP1 SFRP1 GDNF GDNF TGFBR2 TGFBR2 TBX2 TBX2 SEMA4G SEMA4G HEYL HEYL DDX17 DDX17 WNT10A WNT10A SEMA4A SEMA4A PDCD4 PDCD4 BNC2 BNC2 Rtn4 Rtn4 NRP2 NRP2 WNT3A WNT3A HTT HTT MAPK3 MAPK3 WNT2 WNT2 LEF1 LEF1 HOXA5 HOXA5 WNT5A WNT5A WWTR1 WWTR1 NRTN NRTN CPLANE2 CPLANE2 NOG NOG FGF10 FGF10 Snai2 Snai2 LOC101788610 LOC101788610 OTUD5 OTUD5 RBM24 RBM24 SIX4 SIX4 MEF2C MEF2C SOX10 SOX10 HES1 HES1 MDM2 MDM2 PAX2 PAX2 HAS2 HAS2 ANXA6 ANXA6 EXOC4 EXOC4 TGFBR3L TGFBR3L ZFP64 ZFP64 HEY2 HEY2 AKNA AKNA DACT3 DACT3 H0WBR6_CAVPO H0WBR6_CAVPO FAM83D FAM83D KLHL12 KLHL12 HNRNPAB HNRNPAB FOXC2 FOXC2 SEMA7A SEMA7A AMH AMH BMPR1A BMPR1A TCF21 TCF21 Dppa2 Dppa2 PDCD6 PDCD6 RADIL RADIL GSC GSC MEOX1 MEOX1 ZIC2 ZIC2 SNAI1 SNAI1 SEMA5B SEMA5B LOXL3 LOXL3 ROBO2 ROBO2 BCL2 BCL2 OLFM1 OLFM1 NKX2-5 NKX2-5 SCX SCX EPHA3 EPHA3 SOX11 SOX11 FGF8 FGF8 Actl10 Actl10 NCKAP1 NCKAP1 H0VW66_CAVPO H0VW66_CAVPO HAND1 HAND1 GBX2 GBX2 CYP26A1 CYP26A1 PHOX2B PHOX2B NODAL NODAL POLR1B POLR1B SIX2 SIX2 EDNRB EDNRB TBX20 TBX20 FRZB FRZB TGFBR1 TGFBR1 ERBB3 ERBB3 THBS1 THBS1 TRIP10 TRIP10 PKD2 PKD2 TBX5 TBX5 RANBP3L RANBP3L GSK3B GSK3B RET RET SEMA4C SEMA4C FAM172A FAM172A SMAD2 SMAD2 SEMA3C SEMA3C DLL3 DLL3 SEMA3B SEMA3B H0VN16_CAVPO H0VN16_CAVPO SMO SMO MAPK1 MAPK1 EXT1 EXT1 TCF15 TCF15 FN1 FN1 TASOR TASOR KBTBD8 KBTBD8 ROCK2 ROCK2 FOLR1 FOLR1 DCHS1 DCHS1 TBX1 TBX1 TAF10 TAF10 SEMA3E SEMA3E ACTA2 ACTA2 SEMA3D SEMA3D ERBB4 ERBB4 PLAUR PLAUR ROCK1 ROCK1 NUP133 NUP133 ACTC1 ACTC1 ROBO1 ROBO1 LOXL2 LOXL2 LAMA5 LAMA5 SEMA4B SEMA4B RFLNB RFLNB WNT11 WNT11 NRP1 NRP1 CUL7 CUL7 POGLUT1 POGLUT1 ACVR1 ACVR1 MDM4 MDM4 SEMA3F SEMA3F FGF19 FGF19 AMER1 AMER1 TGFB2 TGFB2 CHRD CHRD PAX6 PAX6 HNF1A HNF1A TGFBR3 TGFBR3 PEF1 PEF1 DDX5 DDX5 RBPJ RBPJ NFATC1 NFATC1 TBX3 TBX3 CYP26C1 CYP26C1 EPB41L5 EPB41L5 SEMA3A SEMA3A CITED2 CITED2 ALDH1A2 ALDH1A2 PAX1 PAX1 TCOF1 TCOF1 SOX8 SOX8 ZIC3 ZIC3 ACTA1 ACTA1 OSR1 OSR1 ACVRL1 ACVRL1 CORO1C CORO1C TGFB1 TGFB1 ADAM15 ADAM15 FOXF1 FOXF1 Rdh10 Rdh10 NEDD4 NEDD4 Notch4 Notch4 ENG ENG HTR2B HTR2B APLNR APLNR TFAP2A TFAP2A SEMA6D SEMA6D BMP4 BMP4 CRELD1 CRELD1 FGFR1 FGFR1 SMAD4 SMAD4 SEMA5A SEMA5A PAX3 PAX3 Gata4 Gata4 PDGFRB PDGFRB SEMA4F SEMA4F ISL1 ISL1 Trim28 Trim28 H0V5N2_CAVPO H0V5N2_CAVPO DLG5 DLG5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pitx2Homeobox protein. (325 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (828 aa)
H0V4A5_CAVPOUncharacterized protein. (830 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (399 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (732 aa)
EOMESEomesodermin. (697 aa)
NOS3Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity); Belongs to the NOS family. (1206 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (779 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1903 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1253 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
CTNNB1Catenin beta 1. (781 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
WT1WT1 transcription factor. (320 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
PHACTR4Phosphatase and actin regulator. (713 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
PPP3R1Uncharacterized protein. (169 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (852 aa)
YAP1Yes associated protein 1. (397 aa)
CDC42Cell division cycle 42. (191 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (447 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MSX1Msh homeobox 1. (304 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (990 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
OVOL2Ovo like zinc finger 2. (269 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1063 aa)
MSX2Msh homeobox 2. (267 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (941 aa)
PWWP2APWWP domain containing 2A. (722 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (345 aa)
EDN3Endothelin 3. (200 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (166 aa)
TEAD2TEA domain transcription factor 2. (452 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (271 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
SIX1SIX homeobox 1. (284 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
FLNAFilamin A. (2645 aa)
FGFR2Fibroblast growth factor receptor. (801 aa)
GATA5GATA binding protein 5. (292 aa)
SFRP1Secreted frizzled related protein 1. (307 aa)
GDNFGlial cell derived neurotrophic factor. (210 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TBX2T-box transcription factor 2. (686 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (837 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (729 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (761 aa)
PDCD4Programmed cell death 4. (469 aa)
BNC2Basonuclin 2. (1125 aa)
Rtn4Reticulon. (350 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
HTTHuntingtin. (3133 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
HOXA5Homeobox A5. (270 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
NRTNNeurturin. (197 aa)
CPLANE2Ciliogenesis and planar polarity effector 2. (257 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (210 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Snai2Uncharacterized protein. (268 aa)
LOC101788610Uncharacterized protein. (119 aa)
OTUD5OTU deubiquitinase 5. (571 aa)
RBM24RNA binding motif protein 24. (236 aa)
SIX4SIX homeobox 4. (766 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SOX10SRY-box transcription factor 10. (469 aa)
HES1Hes family bHLH transcription factor 1. (279 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
PAX2Paired box 2. (393 aa)
HAS2Hyaluronan synthase 2. (552 aa)
ANXA6Annexin. (753 aa)
EXOC4Exocyst complex component 4. (975 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (288 aa)
ZFP64ZFP64 zinc finger protein. (681 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (333 aa)
AKNAAT-hook transcription factor. (1310 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (500 aa)
H0WBR6_CAVPOUncharacterized protein; Belongs to the actin family. (381 aa)
FAM83DFamily with sequence similarity 83 member D. (585 aa)
KLHL12Kelch like family member 12. (568 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (327 aa)
FOXC2Forkhead box C2. (441 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (621 aa)
AMHAnti-Mullerian hormone. (560 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
TCF21Transcription factor 21. (179 aa)
Dppa2Uncharacterized protein. (265 aa)
PDCD6Programmed cell death 6. (189 aa)
RADILRap associating with DIL domain. (1097 aa)
GSCGoosecoid homeobox. (228 aa)
MEOX1Mesenchyme homeobox 1. (274 aa)
ZIC2Zic family member 2. (523 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
SEMA5BSemaphorin 5B. (1053 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
ROBO2Roundabout guidance receptor 2. (1509 aa)
BCL2BCL2 apoptosis regulator. (183 aa)
OLFM1Olfactomedin 1. (483 aa)
NKX2-5NK2 homeobox 5. (303 aa)
SCXScleraxis bHLH transcription factor. (199 aa)
EPHA3EPH receptor A3. (933 aa)
SOX11Transcription factor SOX. (377 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (308 aa)
Actl10Uncharacterized protein; Belongs to the actin family. (393 aa)
NCKAP1NCK associated protein 1. (1140 aa)
H0VW66_CAVPOUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
GBX2Gastrulation brain homeobox 2. (338 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
PHOX2BPaired like homeobox 2B. (284 aa)
NODALNodal growth differentiation factor. (351 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1135 aa)
SIX2SIX homeobox 2. (298 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa)
TBX20T-box transcription factor 20. (446 aa)
FRZBFrizzled related protein. (325 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1336 aa)
THBS1Thrombospondin 1. (1163 aa)
TRIP10Thyroid hormone receptor interactor 10. (546 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (839 aa)
TBX5T-box transcription factor 5. (518 aa)
RANBP3LRAN binding protein 3 like. (408 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (831 aa)
FAM172AFamily with sequence similarity 172 member A. (308 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (787 aa)
DLL3Delta like canonical Notch ligand 3. (708 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (751 aa)
H0VN16_CAVPOUncharacterized protein. (71 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
TCF15Transcription factor 15. (188 aa)
FN1Fibronectin 1. (2478 aa)
TASORTranscription activation suppressor. (1362 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (600 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1371 aa)
FOLR1Folate receptor alpha. (160 aa)
DCHS1Dachsous cadherin-related 1. (3297 aa)
TBX1T-box transcription factor 1. (360 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (648 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (776 aa)
ERBB4Receptor protein-tyrosine kinase. (1263 aa)
PLAURPlasminogen activator, urokinase receptor. (309 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
NUP133Nucleoporin 133. (1154 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
ROBO1Roundabout guidance receptor 1. (1612 aa)
LOXL2Lysyl oxidase like 2. (779 aa)
LAMA5Laminin subunit alpha 5. (3609 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (830 aa)
RFLNBRefilin B. (180 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
CUL7Cullin 7; Belongs to the cullin family. (1660 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (485 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
AMER1APC membrane recruitment protein 1. (1127 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (440 aa)
CHRDChordin. (892 aa)
PAX6Paired box 6. (436 aa)
HNF1AHNF1 homeobox A. (628 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
PEF1Penta-EF-hand domain containing 1. (263 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (518 aa)
NFATC1Nuclear factor of activated T cells 1. (928 aa)
TBX3T-box transcription factor 3. (739 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (517 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (705 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (512 aa)
PAX1Paired box 1. (401 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1601 aa)
SOX8SRY-box transcription factor 8. (462 aa)
ZIC3Zic family member 3. (246 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
ADAM15ADAM metallopeptidase domain 15. (862 aa)
FOXF1Forkhead box F1. (376 aa)
Rdh10Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
NEDD4E3 ubiquitin-protein ligase. (896 aa)
Notch4Uncharacterized protein. (1988 aa)
ENGEndoglin. (653 aa)
HTR2B5-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity [...] (480 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (381 aa)
TFAP2ATranscription factor AP-2 alpha. (437 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
BMP4Bone morphogenetic protein 4. (404 aa)
CRELD1Cysteine rich with EGF like domains 1. (420 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SEMA5ASemaphorin 5A. (1073 aa)
PAX3Paired box 3. (484 aa)
Gata4Uncharacterized protein. (237 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (776 aa)
ISL1ISL LIM homeobox 1. (349 aa)
Trim28Uncharacterized protein. (829 aa)
H0V5N2_CAVPOUncharacterized protein. (259 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1864 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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