35 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100725331	Uncharacterized protein. (1433 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1263 aa)
	F11R	F11 receptor. (299 aa)
	H0VX85_CAVPO	Uncharacterized protein. (184 aa)
	H0VU16_CAVPO	Occludin_ELL domain-containing protein. (144 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1805 aa)
	PECAM1	Platelet and endothelial cell adhesion molecule 1. (743 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1754 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	FOXP3	Forkhead box P3. (432 aa)
	H0V3F2_CAVPO	Uncharacterized protein. (1365 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (399 aa)
	H0V3A7_CAVPO	Uncharacterized protein. (1320 aa)
	FASN	Fatty acid synthase. (2530 aa)
	HPSE	Heparanase. (526 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	EZR	Ezrin. (586 aa)
	Rap1b	Uncharacterized protein. (184 aa)
	Rapgef2	Uncharacterized protein. (1640 aa)
	PPP1R16B	Protein phosphatase 1 regulatory subunit 16B. (568 aa)
	MSN	Moesin. (577 aa)
	ENSCPOP00000028762	Uncharacterized protein. (107 aa)
	AFDN	Afadin, adherens junction formation factor. (1794 aa)
	SOX18	SRY-box transcription factor 18. (375 aa)
	PDE2A	Phosphodiesterase. (950 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (926 aa)
	MYADM	Uncharacterized protein. (316 aa)
	F2RL1	F2R like trypsin receptor 1. (399 aa)
	LOC100713271	Uncharacterized protein. (165 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	Tjp2	Uncharacterized protein; Belongs to the MAGUK family. (1176 aa)
	RDX	Radixin. (604 aa)
	PDE4D	Phosphodiesterase. (782 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (294 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFDN	ENSCPOP00000028762	ENSCPOP00000028403	ENSCPOP00000028762	Afadin, adherens junction formation factor.	Uncharacterized protein.	0.848
AFDN	F11R	ENSCPOP00000028403	ENSCPOP00000016860	Afadin, adherens junction formation factor.	F11 receptor.	0.935
AFDN	H0VU16_CAVPO	ENSCPOP00000028403	ENSCPOP00000014187	Afadin, adherens junction formation factor.	Occludin_ELL domain-containing protein.	0.400
AFDN	H0VX85_CAVPO	ENSCPOP00000028403	ENSCPOP00000015314	Afadin, adherens junction formation factor.	Uncharacterized protein.	0.848
AFDN	LOC100713271	ENSCPOP00000028403	ENSCPOP00000023529	Afadin, adherens junction formation factor.	Uncharacterized protein.	0.848
AFDN	RAP1A	ENSCPOP00000028403	ENSCPOP00000033038	Afadin, adherens junction formation factor.	RAP1A, member of RAS oncogene family.	0.914
AFDN	Rap1b	ENSCPOP00000028403	ENSCPOP00000032607	Afadin, adherens junction formation factor.	Uncharacterized protein.	0.871
AFDN	TJP1	ENSCPOP00000028403	ENSCPOP00000009819	Afadin, adherens junction formation factor.	Tight junction protein 1; Belongs to the MAGUK family.	0.957
AFDN	Tjp2	ENSCPOP00000028403	ENSCPOP00000023160	Afadin, adherens junction formation factor.	Uncharacterized protein; Belongs to the MAGUK family.	0.955
CLDN1	CLDN3	ENSCPOP00000023268	ENSCPOP00000007745	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.762
CLDN1	F11R	ENSCPOP00000023268	ENSCPOP00000016860	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	F11 receptor.	0.570
CLDN1	H0VU16_CAVPO	ENSCPOP00000023268	ENSCPOP00000014187	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Occludin_ELL domain-containing protein.	0.549
CLDN1	TJP1	ENSCPOP00000023268	ENSCPOP00000009819	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 1; Belongs to the MAGUK family.	0.983
CLDN1	Tjp2	ENSCPOP00000023268	ENSCPOP00000023160	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein; Belongs to the MAGUK family.	0.902
CLDN3	CLDN1	ENSCPOP00000007745	ENSCPOP00000023268	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.762
CLDN3	TJP1	ENSCPOP00000007745	ENSCPOP00000009819	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 1; Belongs to the MAGUK family.	0.912
CLDN3	Tjp2	ENSCPOP00000007745	ENSCPOP00000023160	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein; Belongs to the MAGUK family.	0.837
EDNRA	EDNRB	ENSCPOP00000004109	ENSCPOP00000013944	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	0.906
EDNRB	EDNRA	ENSCPOP00000013944	ENSCPOP00000004109	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.906
ENSCPOP00000028762	AFDN	ENSCPOP00000028762	ENSCPOP00000028403	Uncharacterized protein.	Afadin, adherens junction formation factor.	0.848