STRINGSTRING
WNT3A WNT3A PIP5K1C PIP5K1C UBASH3B UBASH3B FERMT3 FERMT3 FIBP FIBP PEAR1 PEAR1 FGA FGA PLEK PLEK MPL MPL GATA1 GATA1 FGG FGG FGB FGB H0VE70_CAVPO H0VE70_CAVPO TYRO3 TYRO3 PDIA6 PDIA6 Itgb3 Itgb3 PDGFRA PDGFRA FN1 FN1 SLC7A11 SLC7A11 TSPAN32 TSPAN32 COMP COMP RAP2B RAP2B LOC100732158 LOC100732158 STXBP3 STXBP3 STXBP1 STXBP1 PTPN6 PTPN6 P2ry12 P2ry12 LOC100732436 LOC100732436
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (689 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (638 aa)
FERMT3Fermitin family member 3. (663 aa)
FIBPFGF1 intracellular binding protein. (364 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1040 aa)
FGAFibrinogen alpha chain. (775 aa)
PLEKPleckstrin. (350 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (635 aa)
GATA1GATA binding protein 1. (401 aa)
FGGFibrinogen gamma chain. (445 aa)
FGBFibrinogen beta chain. (479 aa)
H0VE70_CAVPOUncharacterized protein. (796 aa)
TYRO3TYRO3 protein tyrosine kinase. (880 aa)
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (445 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (735 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
FN1Fibronectin 1. (2478 aa)
SLC7A11Solute carrier family 7 member 11. (507 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (265 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
LOC100732158Uncharacterized protein. (246 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
P2ry12Uncharacterized protein. (114 aa)
LOC100732436Uncharacterized protein. (327 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (28%) [HD]