14 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1078 aa)
	SLC34A1	Solute carrier family 34 member 1. (638 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa)
	LOC100732158	Uncharacterized protein. (246 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	Cited1	Uncharacterized protein. (61 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (390 aa)
	SOST	Sclerostin. (202 aa)
	FGF23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (257 aa)
	PHEX	Phosphate regulating endopeptidase homolog X-linked. (749 aa)
	H0VE70_CAVPO	Uncharacterized protein. (796 aa)
	LOC100732436	Uncharacterized protein. (327 aa)
	Prkaca	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF23	PHEX	ENSCPOP00000005141	ENSCPOP00000005576	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Phosphate regulating endopeptidase homolog X-linked.	0.749
FGF23	PTH	ENSCPOP00000005141	ENSCPOP00000003513	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.775
FGF23	SLC34A1	ENSCPOP00000005141	ENSCPOP00000003644	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Solute carrier family 34 member 1.	0.556
FGF23	SOST	ENSCPOP00000005141	ENSCPOP00000030358	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Sclerostin.	0.540
H0VE70_CAVPO	LOC100732158	ENSCPOP00000008303	ENSCPOP00000021644	Uncharacterized protein.	Uncharacterized protein.	0.721
H0VE70_CAVPO	LOC100732436	ENSCPOP00000008303	ENSCPOP00000031430	Uncharacterized protein.	Uncharacterized protein.	0.598
H0VE70_CAVPO	PTH	ENSCPOP00000008303	ENSCPOP00000003513	Uncharacterized protein.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.795
HDAC4	MEF2C	ENSCPOP00000011770	ENSCPOP00000022317	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte enhancer factor 2C.	0.924
LOC100732158	H0VE70_CAVPO	ENSCPOP00000021644	ENSCPOP00000008303	Uncharacterized protein.	Uncharacterized protein.	0.721
LOC100732158	LOC100732436	ENSCPOP00000021644	ENSCPOP00000031430	Uncharacterized protein.	Uncharacterized protein.	0.721
LOC100732436	H0VE70_CAVPO	ENSCPOP00000031430	ENSCPOP00000008303	Uncharacterized protein.	Uncharacterized protein.	0.598
LOC100732436	LOC100732158	ENSCPOP00000031430	ENSCPOP00000021644	Uncharacterized protein.	Uncharacterized protein.	0.721
LOC100732436	PTH	ENSCPOP00000031430	ENSCPOP00000003513	Uncharacterized protein.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.795
LOC100732436	Prkaca	ENSCPOP00000031430	ENSCPOP00000032930	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.437
MEF2C	HDAC4	ENSCPOP00000022317	ENSCPOP00000011770	Myocyte enhancer factor 2C.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.924
PHEX	FGF23	ENSCPOP00000005576	ENSCPOP00000005141	Phosphate regulating endopeptidase homolog X-linked.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.749
PHEX	PTH	ENSCPOP00000005576	ENSCPOP00000003513	Phosphate regulating endopeptidase homolog X-linked.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.520
PHEX	SLC34A1	ENSCPOP00000005576	ENSCPOP00000003644	Phosphate regulating endopeptidase homolog X-linked.	Solute carrier family 34 member 1.	0.558
PHEX	SOST	ENSCPOP00000005576	ENSCPOP00000030358	Phosphate regulating endopeptidase homolog X-linked.	Sclerostin.	0.542
PTH	FGF23	ENSCPOP00000003513	ENSCPOP00000005141	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.775