14 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	Prkaca	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	LOC100732436	Uncharacterized protein. (327 aa)
	SOST	Sclerostin. (202 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (390 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	LOC100732158	Uncharacterized protein. (246 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1078 aa)
	H0VE70_CAVPO	Uncharacterized protein. (796 aa)
	PHEX	Phosphate regulating endopeptidase homolog X-linked. (749 aa)
	FGF23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (257 aa)
	SLC34A1	Solute carrier family 34 member 1. (638 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
	Cited1	Uncharacterized protein. (61 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF23	PHEX	ENSCPOP00000005141	ENSCPOP00000005576	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Phosphate regulating endopeptidase homolog X-linked.	0.749
FGF23	PTH	ENSCPOP00000005141	ENSCPOP00000003513	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.775
FGF23	SLC34A1	ENSCPOP00000005141	ENSCPOP00000003644	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Solute carrier family 34 member 1.	0.556
FGF23	SOST	ENSCPOP00000005141	ENSCPOP00000030358	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Sclerostin.	0.540
H0VE70_CAVPO	LOC100732158	ENSCPOP00000008303	ENSCPOP00000021644	Uncharacterized protein.	Uncharacterized protein.	0.721
H0VE70_CAVPO	LOC100732436	ENSCPOP00000008303	ENSCPOP00000031430	Uncharacterized protein.	Uncharacterized protein.	0.598
H0VE70_CAVPO	PTH	ENSCPOP00000008303	ENSCPOP00000003513	Uncharacterized protein.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.795
HDAC4	MEF2C	ENSCPOP00000011770	ENSCPOP00000022317	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte enhancer factor 2C.	0.924
LOC100732158	H0VE70_CAVPO	ENSCPOP00000021644	ENSCPOP00000008303	Uncharacterized protein.	Uncharacterized protein.	0.721
LOC100732158	LOC100732436	ENSCPOP00000021644	ENSCPOP00000031430	Uncharacterized protein.	Uncharacterized protein.	0.721
LOC100732436	H0VE70_CAVPO	ENSCPOP00000031430	ENSCPOP00000008303	Uncharacterized protein.	Uncharacterized protein.	0.598
LOC100732436	LOC100732158	ENSCPOP00000031430	ENSCPOP00000021644	Uncharacterized protein.	Uncharacterized protein.	0.721
LOC100732436	PTH	ENSCPOP00000031430	ENSCPOP00000003513	Uncharacterized protein.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.795
LOC100732436	Prkaca	ENSCPOP00000031430	ENSCPOP00000032930	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.437
MEF2C	HDAC4	ENSCPOP00000022317	ENSCPOP00000011770	Myocyte enhancer factor 2C.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.924
PHEX	FGF23	ENSCPOP00000005576	ENSCPOP00000005141	Phosphate regulating endopeptidase homolog X-linked.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.749
PHEX	PTH	ENSCPOP00000005576	ENSCPOP00000003513	Phosphate regulating endopeptidase homolog X-linked.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.520
PHEX	SLC34A1	ENSCPOP00000005576	ENSCPOP00000003644	Phosphate regulating endopeptidase homolog X-linked.	Solute carrier family 34 member 1.	0.558
PHEX	SOST	ENSCPOP00000005576	ENSCPOP00000030358	Phosphate regulating endopeptidase homolog X-linked.	Sclerostin.	0.542
PTH	FGF23	ENSCPOP00000003513	ENSCPOP00000005141	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.775