12 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	FOXA2	Forkhead box A2. (459 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	Hhex	Homeobox domain-containing protein. (98 aa)
	Gdf3	TGF_BETA_2 domain-containing protein. (359 aa)
	SRF	Serum response factor. (461 aa)
	LHX1	LIM homeobox 1. (406 aa)
	NODAL	Nodal growth differentiation factor. (351 aa)
	ETS2	ETS proto-oncogene 2, transcription factor. (447 aa)
	OTX2	Orthodenticle homeobox 2. (289 aa)
	ZIC3	Zic family member 3. (246 aa)
	H0UXD4_CAVPO	TGF_BETA_2 domain-containing protein. (359 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ETS2	SRF	ENSCPOP00000013532	ENSCPOP00000015471	ETS proto-oncogene 2, transcription factor.	Serum response factor.	0.913
FOXA2	Hhex	ENSCPOP00000026387	ENSCPOP00000023313	Forkhead box A2.	Homeobox domain-containing protein.	0.510
FOXA2	OTX2	ENSCPOP00000026387	ENSCPOP00000003090	Forkhead box A2.	Orthodenticle homeobox 2.	0.705
Gdf3	NODAL	ENSCPOP00000018739	ENSCPOP00000014277	TGF_BETA_2 domain-containing protein.	Nodal growth differentiation factor.	0.687
H0UXD4_CAVPO	NODAL	ENSCPOP00000001748	ENSCPOP00000014277	TGF_BETA_2 domain-containing protein.	Nodal growth differentiation factor.	0.687
Hhex	FOXA2	ENSCPOP00000023313	ENSCPOP00000026387	Homeobox domain-containing protein.	Forkhead box A2.	0.510
Hhex	OTX2	ENSCPOP00000023313	ENSCPOP00000003090	Homeobox domain-containing protein.	Orthodenticle homeobox 2.	0.643
LHX1	OTX2	ENSCPOP00000014380	ENSCPOP00000003090	LIM homeobox 1.	Orthodenticle homeobox 2.	0.420
LHX1	SRF	ENSCPOP00000014380	ENSCPOP00000015471	LIM homeobox 1.	Serum response factor.	0.574
LRP6	WNT5A	ENSCPOP00000027686	ENSCPOP00000023342	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.936
NODAL	Gdf3	ENSCPOP00000014277	ENSCPOP00000018739	Nodal growth differentiation factor.	TGF_BETA_2 domain-containing protein.	0.687
NODAL	H0UXD4_CAVPO	ENSCPOP00000014277	ENSCPOP00000001748	Nodal growth differentiation factor.	TGF_BETA_2 domain-containing protein.	0.687
NODAL	ZIC3	ENSCPOP00000014277	ENSCPOP00000002158	Nodal growth differentiation factor.	Zic family member 3.	0.555
OTX2	FOXA2	ENSCPOP00000003090	ENSCPOP00000026387	Orthodenticle homeobox 2.	Forkhead box A2.	0.705
OTX2	Hhex	ENSCPOP00000003090	ENSCPOP00000023313	Orthodenticle homeobox 2.	Homeobox domain-containing protein.	0.643
OTX2	LHX1	ENSCPOP00000003090	ENSCPOP00000014380	Orthodenticle homeobox 2.	LIM homeobox 1.	0.420
OTX2	ZIC3	ENSCPOP00000003090	ENSCPOP00000002158	Orthodenticle homeobox 2.	Zic family member 3.	0.450
SRF	ETS2	ENSCPOP00000015471	ENSCPOP00000013532	Serum response factor.	ETS proto-oncogene 2, transcription factor.	0.913
SRF	LHX1	ENSCPOP00000015471	ENSCPOP00000014380	Serum response factor.	LIM homeobox 1.	0.574
WNT5A	LRP6	ENSCPOP00000023342	ENSCPOP00000027686	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.936