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LOC100730472 LOC100730472 SEC14L2 SEC14L2 Ces1d Ces1d APOE APOE ABCG4 ABCG4 CYP7A1 CYP7A1 ABCG1 ABCG1 SREBF1 SREBF1 FDPS FDPS H0VU94_CAVPO H0VU94_CAVPO SCAP SCAP ENSCPOP00000022046 ENSCPOP00000022046 LOC100717473 LOC100717473 ENSCPOP00000024925 ENSCPOP00000024925 ENSCPOP00000024929 ENSCPOP00000024929 FGF1 FGF1 STARD4 STARD4 SREBF2 SREBF2 LOC100721835 LOC100721835 APOA1 APOA1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC100730472Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
SEC14L2Uncharacterized protein. (403 aa)
Ces1dCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (298 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
CYP7A1Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (496 aa)
ABCG1ATP binding cassette subfamily G member 1. (666 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1155 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (352 aa)
H0VU94_CAVPOCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa)
SCAPSREBF chaperone. (1260 aa)
ENSCPOP00000022046Thiolase_N domain-containing protein. (103 aa)
LOC100717473Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa)
ENSCPOP00000024925COesterase domain-containing protein. (295 aa)
ENSCPOP00000024929SCP2 domain-containing protein. (143 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
STARD4StAR related lipid transfer domain containing 4. (208 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1149 aa)
LOC100721835Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (264 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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