node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCG1 | APOA1 | ENSCPOP00000013696 | ENSCPOP00000032306 | ATP binding cassette subfamily G member 1. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | 0.861 |
ABCG1 | APOE | ENSCPOP00000013696 | ENSCPOP00000006519 | ATP binding cassette subfamily G member 1. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.737 |
ABCG1 | CYP7A1 | ENSCPOP00000013696 | ENSCPOP00000003062 | ATP binding cassette subfamily G member 1. | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.570 |
ABCG1 | SREBF1 | ENSCPOP00000013696 | ENSCPOP00000002221 | ATP binding cassette subfamily G member 1. | Sterol regulatory element binding transcription factor 1. | 0.490 |
ABCG1 | SREBF2 | ENSCPOP00000013696 | ENSCPOP00000027507 | ATP binding cassette subfamily G member 1. | Sterol regulatory element binding transcription factor 2. | 0.564 |
ABCG4 | APOA1 | ENSCPOP00000005848 | ENSCPOP00000032306 | ATP binding cassette subfamily G member 4. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | 0.764 |
APOA1 | ABCG1 | ENSCPOP00000032306 | ENSCPOP00000013696 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | ATP binding cassette subfamily G member 1. | 0.861 |
APOA1 | ABCG4 | ENSCPOP00000032306 | ENSCPOP00000005848 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | ATP binding cassette subfamily G member 4. | 0.764 |
APOA1 | APOE | ENSCPOP00000032306 | ENSCPOP00000006519 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.969 |
APOE | ABCG1 | ENSCPOP00000006519 | ENSCPOP00000013696 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | ATP binding cassette subfamily G member 1. | 0.737 |
APOE | APOA1 | ENSCPOP00000006519 | ENSCPOP00000032306 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | 0.969 |
APOE | CYP7A1 | ENSCPOP00000006519 | ENSCPOP00000003062 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.420 |
APOE | SEC14L2 | ENSCPOP00000006519 | ENSCPOP00000013148 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Uncharacterized protein. | 0.483 |
CYP7A1 | ABCG1 | ENSCPOP00000003062 | ENSCPOP00000013696 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | ATP binding cassette subfamily G member 1. | 0.570 |
CYP7A1 | APOE | ENSCPOP00000003062 | ENSCPOP00000006519 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.420 |
CYP7A1 | SREBF1 | ENSCPOP00000003062 | ENSCPOP00000002221 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | Sterol regulatory element binding transcription factor 1. | 0.498 |
CYP7A1 | SREBF2 | ENSCPOP00000003062 | ENSCPOP00000027507 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | Sterol regulatory element binding transcription factor 2. | 0.515 |
ENSCPOP00000022046 | ENSCPOP00000024929 | ENSCPOP00000022046 | ENSCPOP00000024929 | Thiolase_N domain-containing protein. | SCP2 domain-containing protein. | 0.997 |
ENSCPOP00000024929 | ENSCPOP00000022046 | ENSCPOP00000024929 | ENSCPOP00000022046 | SCP2 domain-containing protein. | Thiolase_N domain-containing protein. | 0.997 |
FDPS | SREBF1 | ENSCPOP00000013849 | ENSCPOP00000002221 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Sterol regulatory element binding transcription factor 1. | 0.417 |