STRINGSTRING
ATP1B2 ATP1B2 FYN FYN ADGRG1 ADGRG1 KCNJ10 KCNJ10 EIF2S1 EIF2S1 GPR161 GPR161 TMEM50A TMEM50A NFASC NFASC KCNK2 KCNK2 EZR EZR ITGB1 ITGB1 GJB2 GJB2 AKR1B1 AKR1B1 LCP1 LCP1 FMR1 FMR1 GRM2 GRM2 SLC1A2 SLC1A2 SLC17A8 SLC17A8 DMD DMD SYT4 SYT4 H0VFY3_CAVPO H0VFY3_CAVPO ABCA7 ABCA7 WASF3 WASF3 SLC2A13 SLC2A13 SLC1A1 SLC1A1 Mapt Mapt SLC7A11 SLC7A11 GRM3 GRM3 SCN7A SCN7A SLC4A8 SLC4A8 PINK1 PINK1 MLC1 MLC1 CNGA3 CNGA3 GFAP GFAP LGALS3 LGALS3 MT3 MT3 AQP4 AQP4 SIRT2 SIRT2 GLUL GLUL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (252 aa)
FYNTyrosine-protein kinase. (537 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (579 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (548 aa)
TMEM50ATransmembrane protein 50A. (157 aa)
NFASCNeurofascin. (1346 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
EZREzrin. (586 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
FMR1Fragile X mental retardation 1. (612 aa)
GRM2Glutamate metabotropic receptor 2. (871 aa)
SLC1A2Amino acid transporter. (573 aa)
SLC17A8Solute carrier family 17 member 8. (476 aa)
DMDDystrophin. (3613 aa)
SYT4Synaptotagmin 4. (425 aa)
H0VFY3_CAVPOUncharacterized protein. (674 aa)
ABCA7ATP binding cassette subfamily A member 7. (2108 aa)
WASF3WASP family member 3. (502 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (560 aa)
SLC1A1Amino acid transporter. (525 aa)
MaptMicrotubule-associated protein. (370 aa)
SLC7A11Solute carrier family 7 member 11. (507 aa)
GRM3Glutamate metabotropic receptor 3. (877 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1520 aa)
SLC4A8Anion exchange protein. (1090 aa)
PINK1PTEN induced kinase 1. (574 aa)
MLC1Modulator of VRAC current 1. (388 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (647 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (431 aa)
LGALS3Galectin. (244 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (66 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (352 aa)
GLULGlutamine synthetase. (373 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.