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CDH10 CDH10 PAK1 PAK1 PHB PHB CALB1 CALB1 IGSF9B IGSF9B GABRA3 GABRA3 KCND3 KCND3 MDGA2 MDGA2 GABRG2 GABRG2 DRD3 DRD3 GABRD GABRD SNAP23 SNAP23 C1QBP C1QBP GABRA5 GABRA5 SLITRK3 SLITRK3 LRFN5 LRFN5 GIT1 GIT1 GABRB3 GABRB3 GABBR2 GABBR2 LRFN4 LRFN4 Gap43 Gap43 Cntnap4 Cntnap4 GABRA1 GABRA1 CAMK4 CAMK4 RIMS2 RIMS2 NRG1 NRG1 SLC6A11 SLC6A11 CLSTN3 CLSTN3 SLC32A1 SLC32A1 ERC1 ERC1 ACAN ACAN DRD2 DRD2 PCLO PCLO GABRA4 GABRA4 EFNA5 EFNA5 GABRA6 GABRA6 CSPG5 CSPG5 SV2A SV2A ARHGEF7 ARHGEF7 CDH13 CDH13 GABRR1 GABRR1 GABRR2 GABRR2 GUCY1A1 GUCY1A1 ERBB4 ERBB4 CNTN5 CNTN5 CBLN4 CBLN4 KCND2 KCND2 ERC2 ERC2 GPHN GPHN NRXN3 NRXN3 IQSEC3 IQSEC3 SLITRK1 SLITRK1 PTPRO PTPRO BCAN BCAN CACNA1E CACNA1E SLC6A6 SLC6A6 LRRTM2 LRRTM2 H0VSR6_CAVPO H0VSR6_CAVPO GABRB2 GABRB2 MAGI2 MAGI2 Rps27 Rps27 EPHA3 EPHA3 LOC100716847 LOC100716847 GRM7 GRM7 NLGN1 NLGN1 NRG2 NRG2 SLC6A1 SLC6A1 LRRTM1 LRRTM1 CTBP1 CTBP1 GABRA2 GABRA2 ATP2B2 ATP2B2 PHB2 PHB2 H0WA79_CAVPO H0WA79_CAVPO CNR1 CNR1 GABRE GABRE NLGN2 NLGN2 Drd4 Drd4 GABRB1 GABRB1 GABBR1 GABBR1 NPTN NPTN ATP2B1 ATP2B1 NLGN3 NLGN3 PLCB1 PLCB1 ABHD6 ABHD6 FLOT1 FLOT1 ARHGEF9 ARHGEF9 DRD1 DRD1 CLSTN1 CLSTN1 DAG1 DAG1 ENSCPOP00000027747 ENSCPOP00000027747 ENSCPOP00000027864 ENSCPOP00000027864 SEPTIN11 SEPTIN11 GLRB GLRB BSN BSN ITPR1 ITPR1 ATP2B3 ATP2B3 ENSCPOP00000030659 ENSCPOP00000030659 HTR1A HTR1A BAIAP3 BAIAP3 ENSCPOP00000031834 ENSCPOP00000031834 MDGA1 MDGA1 NR3C2 NR3C2 CTBP2 CTBP2 SYT7 SYT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (705 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PHBProhibitin. (272 aa)
CALB1Calbindin 1. (275 aa)
IGSF9BImmunoglobulin superfamily member 9B. (1369 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (505 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2. (944 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (364 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (222 aa)
C1QBPComplement C1q binding protein. (281 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
SLITRK3SLIT and NTRK like family member 3. (964 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (719 aa)
GIT1GIT ArfGAP 1. (757 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (820 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (635 aa)
Gap43Uncharacterized protein. (211 aa)
Cntnap4Uncharacterized protein. (1298 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (418 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1410 aa)
NRG1Neuregulin 1. (700 aa)
SLC6A11Solute carrier family 6 member 11. (640 aa)
CLSTN3Calsyntenin 3. (959 aa)
SLC32A1Solute carrier family 32 member 1. (526 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1116 aa)
ACANAggrecan. (2119 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PCLOPiccolo presynaptic cytomatrix protein. (3548 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (576 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (521 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (753 aa)
CDH13Cadherin 13. (713 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (480 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
ERBB4Receptor protein-tyrosine kinase. (1263 aa)
CNTN5Contactin 5. (1099 aa)
CBLN4Cerebellin 4 precursor. (201 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (975 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (709 aa)
NRXN3Neurexin 3. (1571 aa)
IQSEC3IQ motif and Sec7 domain 3. (1166 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
BCANBrevican. (899 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
H0VSR6_CAVPOUncharacterized protein. (327 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1237 aa)
Rps2740S ribosomal protein S27. (84 aa)
EPHA3EPH receptor A3. (933 aa)
LOC100716847Uncharacterized protein. (80 aa)
GRM7Glutamate metabotropic receptor 7. (922 aa)
NLGN1Neuroligin 1. (843 aa)
NRG2Neuregulin 2. (705 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (589 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (346 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa)
PHB2Prohibitin. (299 aa)
H0WA79_CAVPOANF_receptor domain-containing protein. (187 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
NLGN2Neuroligin 2. (662 aa)
Drd4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (419 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (844 aa)
NPTNNeuroplastin. (397 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
NLGN3Neuroligin 3. (846 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (518 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (444 aa)
CLSTN1Calsyntenin 1. (989 aa)
DAG1Dystroglycan 1. (891 aa)
ENSCPOP00000027747LAM_G_DOMAIN domain-containing protein. (151 aa)
ENSCPOP00000027864Uncharacterized protein. (121 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
BSNBassoon presynaptic cytomatrix protein. (3843 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1226 aa)
ENSCPOP00000030659G_PROTEIN_RECEP_F3_4 domain-containing protein. (497 aa)
HTR1A5-hydroxytryptamine receptor 1A. (421 aa)
BAIAP3BAI1 associated protein 3. (1152 aa)
ENSCPOP00000031834Uncharacterized protein. (73 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (962 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (1010 aa)
CTBP2C-terminal binding protein 2. (978 aa)
SYT7Synaptotagmin 7. (556 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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