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| | H0VCE9_CAVPO | Rhodanese domain-containing protein. (335 aa) |
| | Chd4 | Uncharacterized protein. (1900 aa) |
| | RFC3 | Replication factor C subunit 3. (220 aa) |
| | H0WBK1_CAVPO | Uncharacterized protein. (163 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1927 aa) |
| | MLH3 | MutL homolog 3. (1455 aa) |
| | LOC100736130 | Uncharacterized protein. (287 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (298 aa) |
| | ALKBH2 | AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (261 aa) |
| | POLD1 | DNA polymerase. (1134 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | Ercc6l2 | Uncharacterized protein. (1539 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (989 aa) |
| | PTBP1 | Polypyrimidine tract binding protein 1. (557 aa) |
| | TATDN1 | TatD DNase domain containing 1. (297 aa) |
| | ISG20 | Interferon stimulated exonuclease gene 20. (190 aa) |
| | Bivm | Uncharacterized protein. (503 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1021 aa) |
| | OGG1 | 8-oxoguanine DNA glycosylase. (303 aa) |
| | DKC1 | Dyskerin pseudouridine synthase 1. (513 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | CHD1L | Chromodomain helicase DNA binding protein 1 like. (897 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (768 aa) |
| | HELQ | Helicase, POLQ like. (1054 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MAML1 | Mastermind like transcriptional coactivator 1. (794 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | PLD3 | Phospholipase D family member 3. (490 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (409 aa) |
| | LOC100721277 | Uncharacterized protein. (681 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (619 aa) |
| | SUPV3L1 | Suv3 like RNA helicase. (786 aa) |
| | CHTF18 | Chromosome transmission fidelity factor 18. (988 aa) |
| | TDG | Thymine DNA glycosylase. (413 aa) |
| | DFFB | DNA fragmentation factor subunit beta. (302 aa) |
| | EXO1 | Exonuclease 1. (839 aa) |
| | PMS2 | PMS1 homolog 2, mismatch repair system component. (890 aa) |
| | Ttf2 | Uncharacterized protein. (1148 aa) |
| | DNASE2 | Deoxyribonuclease 2, lysosomal. (357 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (696 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (810 aa) |
| | Msh5 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (828 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1336 aa) |
| | POLK | DNA polymerase kappa. (540 aa) |
| | TWNK | Twinkle mtDNA helicase. (670 aa) |
| | TEP1 | Telomerase associated protein 1. (2511 aa) |
| | MSH4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (884 aa) |
| | HLTF | Helicase like transcription factor. (1009 aa) |
| | ERCC5 | ERCC excision repair 5, endonuclease. (1059 aa) |
| | Rad50 | Zinc-hook domain-containing protein. (1275 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1051 aa) |
| | DNTT | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (502 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2583 aa) |
| | DCLRE1C | DNA cross-link repair 1C. (688 aa) |
| | PRIMPOL | Primase and DNA directed polymerase. (547 aa) |
| | POLA1 | DNA polymerase. (1467 aa) |
| | PLD4 | Phospholipase D family member 4. (501 aa) |
| | Pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | TOP3B | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (862 aa) |
| | BLM | BLM RecQ like helicase. (1405 aa) |
| | POLN | DNA polymerase nu. (860 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | ALKBH1 | AlkB homolog 1, histone H2A dioxygenase. (389 aa) |
| | FANCM | FA complementation group M. (1971 aa) |
| | SUB1 | SUB1 regulator of transcription. (127 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (916 aa) |
| | PMS1 | PMS1 homolog 1, mismatch repair system component. (930 aa) |
| | N6AMT1 | N-6 adenine-specific DNA methyltransferase 1. (214 aa) |
| | Dclre1b | Lactamase_B domain-containing protein. (190 aa) |
| | UNG-2 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (311 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (739 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa) |
| | EXO5 | Exonuclease 5. (373 aa) |
| | ENSCPOP00000025543 | AAA_12 domain-containing protein. (243 aa) |
| | Tm4sf19 | Uncharacterized protein. (232 aa) |
| | DNASE1L3 | Deoxyribonuclease; Belongs to the DNase I family. (302 aa) |
| | DNASE1L2 | Deoxyribonuclease; Belongs to the DNase I family. (278 aa) |
| | HAUS3 | HAUS augmin like complex subunit 3. (603 aa) |
| | Mcm8 | MCM domain-containing protein; Belongs to the MCM family. (833 aa) |
| | POLH | DNA polymerase eta. (712 aa) |
| | ENSCPOP00000027851 | Bromo domain-containing protein. (228 aa) |
| | LOC100715543 | DEAD-box helicase 1. (502 aa) |
| | CECR2 | CECR2 histone acetyl-lysine reader. (1413 aa) |
| | Rps3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | MPG | N-methylpurine DNA glycosylase. (300 aa) |
| | EP400 | E1A binding protein p400. (3128 aa) |
| | EXOG | Exo/endonuclease G. (358 aa) |
| | DHX9 | DExH-box helicase 9. (1373 aa) |
| | APTX | Aprataxin. (341 aa) |
| | PTGES3 | Prostaglandin E synthase 3. (160 aa) |
| | ENSCPOP00000029431 | Uncharacterized protein. (111 aa) |
| | MGME1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family. (356 aa) |
| | CHD9 | Chromodomain helicase DNA binding protein 9. (2804 aa) |
| | GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) |
| | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (781 aa) |
| | HELLS | Helicase, lymphoid specific. (838 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (898 aa) |
| | SMUG1 | Single-strand-selective monofunctional uracil-DNA glycosylase 1. (272 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1027 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (465 aa) |
| | Cep41 | Rhodanese domain-containing protein. (373 aa) |
| | HMGA1 | High mobility group AT-hook 1. (108 aa) |
| | RAD51D | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (329 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1473 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1614 aa) |
| | TERF2 | Telomeric repeat binding factor 2. (542 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (300 aa) |
| | TOP1MT | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (629 aa) |
| | POLI | DNA polymerase iota. (662 aa) |
| | ALKBH4 | AlkB homolog 4, lysine demethylase. (215 aa) |
| | Slx1a | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (266 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1600 aa) |
| | REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (2940 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (731 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (481 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (903 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2003 aa) |
| | RFC5 | Replication factor C subunit 5. (340 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (401 aa) |
| | RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (650 aa) |
| | XRCC3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (338 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1109 aa) |
| | NAV2 | Neuron navigator 2. (2385 aa) |
| | TREX2 | Three prime repair exonuclease 2. (236 aa) |
| | TREX1 | Three prime repair exonuclease 1. (314 aa) |
| | CHD6 | Chromodomain helicase DNA binding protein 6. (2716 aa) |
| | RECQL4 | RecQ like helicase 4. (1226 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1018 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1636 aa) |
| | H0VSI3_CAVPO | DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (677 aa) |
| | POLM | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (485 aa) |
| | SHPRH | SNF2 histone linker PHD RING helicase. (1665 aa) |
| | CDK7 | Cyclin dependent kinase 7. (335 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (706 aa) |
| | Rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1246 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa) |
| | DCLRE1A | DNA cross-link repair 1A. (913 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | ASCC3 | Activating signal cointegrator 1 complex subunit 3. (2185 aa) |
| | WRN | WRN RecQ like helicase. (1462 aa) |
| | HELB | DNA helicase B. (1063 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa) |
| | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1056 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2996 aa) |
| | FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (987 aa) |
| | H0VN16_CAVPO | Uncharacterized protein. (71 aa) |
| | LIG3 | DNA ligase. (1012 aa) |
| | FTO | FTO alpha-ketoglutarate dependent dioxygenase. (499 aa) |
| | WRNIP1 | WRN helicase interacting protein 1. (568 aa) |
| | Mutyh | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (530 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (280 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (938 aa) |
| | TDP1 | Tyrosyl-DNA phosphodiesterase 1. (607 aa) |
| | REV1 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1251 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1831 aa) |
| | MPHOSPH9 | M-phase phosphoprotein 9. (970 aa) |
| | SPO11 | SPO11 initiator of meiotic double stranded breaks. (396 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (971 aa) |
| | Rad54b | Uncharacterized protein. (901 aa) |
| | DNASE2B | Deoxyribonuclease 2 beta. (361 aa) |
| | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase. (1238 aa) |
| | SMARCAD1 | Uncharacterized protein. (1032 aa) |
| | INO80 | INO80 complex ATPase subunit. (1558 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | MSH3 | MutS homolog 3. (1047 aa) |
| | NEIL1 | Nei like DNA glycosylase 1. (401 aa) |
| | RAD51B | RAD51 paralog B. (258 aa) |
| | Srcap | Uncharacterized protein. (3171 aa) |
| | FBH1 | F-box DNA helicase 1. (1012 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (340 aa) |
| | REXO2 | RNA exonuclease 2. (237 aa) |
| | PGBD5 | PiggyBac transposable element derived 5. (519 aa) |
| | ARID1A | AT-rich interaction domain 1A. (1903 aa) |
| | H0VGS2_CAVPO | Uncharacterized protein. (611 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (260 aa) |
| | NEIL3 | Nei like DNA glycosylase 3. (607 aa) |
| | CHD1 | Chromodomain helicase DNA binding protein 1. (1666 aa) |
| | APLF | Aprataxin and PNKP like factor. (498 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (609 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | DDX11 | DEAD/H-box helicase 11. (878 aa) |
| | BTAF1 | B-TFIID TATA-box binding protein associated factor 1. (1856 aa) |
| | MLH1 | MutL homolog 1. (758 aa) |
| | Lig1 | DNA ligase. (909 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1903 aa) |
| | RFC1 | Replication factor C subunit 1. (1153 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) |
| | ENDOG | Endonuclease. (299 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (486 aa) |
| | RAD51C | RAD51 paralog C. (373 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | H0V4D6_CAVPO | Uncharacterized protein. (176 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1433 aa) |
| | NME1 | Nucleoside diphosphate kinase. (152 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1117 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1588 aa) |
| | POLL | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (594 aa) |
| | C17orf64 | Chromosome 17 open reading frame 64. (220 aa) |
| | ENDOV | Endonuclease V. (260 aa) |
| | DNASE1L1 | Deoxyribonuclease; Belongs to the DNase I family. (307 aa) |
| | CHD2 | Uncharacterized protein. (1689 aa) |
| | METTL4 | Methyltransferase like 4; Belongs to the MT-A70-like family. (470 aa) |
| | RAD54L2 | RAD54 like 2. (1467 aa) |
| | NEIL2 | Nei like DNA glycosylase 2. (336 aa) |
| | TDP2 | Tyrosyl-DNA phosphodiesterase 2. (358 aa) |
| | RAD54L | RAD54 like. (748 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1540 aa) |
| | Ankle1 | Uncharacterized protein. (520 aa) |
| | IGHMBP2 | Immunoglobulin mu DNA binding protein 2. (1051 aa) |
| | POLG2 | DNA polymerase gamma 2, accessory subunit. (482 aa) |
| | APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (514 aa) |
| | POLG | DNA polymerase gamma, catalytic subunit. (1206 aa) |
| | HFM1 | Helicase for meiosis 1. (1400 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (900 aa) |
| | DHX36 | DEAH-box helicase 36. (916 aa) |
| | ATRX | ATRX chromatin remodeler. (2481 aa) |
| | MUS81 | MUS81 structure-specific endonuclease subunit. (562 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (463 aa) |
