37 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	GTF2F1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (522 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa)
	TBPL1	TATA-box binding protein like 1. (179 aa)
	GTF3C5	General transcription factor IIIC subunit 5. (519 aa)
	TAF1C	TATA-box binding protein associated factor, RNA polymerase I subunit C. (837 aa)
	GTF3A	General transcription factor IIIA. (330 aa)
	GTF2H3	General transcription factor IIH subunit 3. (309 aa)
	GTF2E1	General transcription factor IIE subunit 1. (440 aa)
	UBTF	Upstream binding transcription factor. (763 aa)
	H0VCM2_CAVPO	TFIIE beta domain-containing protein. (173 aa)
	GTF3C3	General transcription factor IIIC subunit 3. (883 aa)
	SNAPC4	Small nuclear RNA activating complex polypeptide 4. (1340 aa)
	TBPL2	TATA-box binding protein like 2. (397 aa)
	DRAP1	DR1 associated protein 1. (212 aa)
	PRRX2	Paired related homeobox 2. (225 aa)
	GTF2E2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (293 aa)
	Taf1	Transcription initiation factor TFIID subunit. (1836 aa)
	TAF5	TATA-box binding protein associated factor 5. (762 aa)
	TAF6	TATA-box binding protein associated factor 6. (678 aa)
	GTF3C2	General transcription factor IIIC subunit 2. (910 aa)
	RRN3	RRN3 homolog, RNA polymerase I transcription factor. (658 aa)
	GTF2A1	General transcription factor IIA subunit 1. (377 aa)
	TAF6L	TATA-box binding protein associated factor 6 like. (588 aa)
	Taf7l	TAFII55_N domain-containing protein. (342 aa)
	BRF1	BRF1 RNA polymerase III transcription initiation factor subunit. (677 aa)
	ENSCPOP00000023083	B-block_TFIIIC domain-containing protein. (283 aa)
	GTF2H4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (485 aa)
	PRRX1	Paired related homeobox 1. (245 aa)
	GTF3C4	General transcription factor IIIC subunit 4. (815 aa)
	DR1	Down-regulator of transcription 1. (176 aa)
	TBP	TATA-box binding protein. (321 aa)
	GTF2B	General transcription factor IIB. (308 aa)
	GTF2F2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
	GTF2A2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	TAF7	TATA-box binding protein associated factor 7. (349 aa)
	C11orf88	Chromosome 11 open reading frame 88. (168 aa)
	TAF4	TATA-box binding protein associated factor 4. (637 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRF1	C11orf88	ENSCPOP00000000059	ENSCPOP00000028305	BRF1 RNA polymerase III transcription initiation factor subunit.	Chromosome 11 open reading frame 88.	0.896
BRF1	ENSCPOP00000023083	ENSCPOP00000000059	ENSCPOP00000023083	BRF1 RNA polymerase III transcription initiation factor subunit.	B-block_TFIIIC domain-containing protein.	0.900
BRF1	GTF2B	ENSCPOP00000000059	ENSCPOP00000031343	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIB.	0.557
BRF1	GTF2E1	ENSCPOP00000000059	ENSCPOP00000008664	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIE subunit 1.	0.451
BRF1	GTF3A	ENSCPOP00000000059	ENSCPOP00000009108	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIIA.	0.760
BRF1	GTF3C2	ENSCPOP00000000059	ENSCPOP00000003466	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIIC subunit 2.	0.755
BRF1	GTF3C3	ENSCPOP00000000059	ENSCPOP00000005982	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIIC subunit 3.	0.998
BRF1	GTF3C4	ENSCPOP00000000059	ENSCPOP00000012836	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIIC subunit 4.	0.864
BRF1	GTF3C5	ENSCPOP00000000059	ENSCPOP00000010017	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIIC subunit 5.	0.897
BRF1	RRN3	ENSCPOP00000000059	ENSCPOP00000003351	BRF1 RNA polymerase III transcription initiation factor subunit.	RRN3 homolog, RNA polymerase I transcription factor.	0.406
BRF1	SNAPC4	ENSCPOP00000000059	ENSCPOP00000005602	BRF1 RNA polymerase III transcription initiation factor subunit.	Small nuclear RNA activating complex polypeptide 4.	0.615
BRF1	TBP	ENSCPOP00000000059	ENSCPOP00000031711	BRF1 RNA polymerase III transcription initiation factor subunit.	TATA-box binding protein.	0.985
BRF1	TBPL1	ENSCPOP00000000059	ENSCPOP00000010705	BRF1 RNA polymerase III transcription initiation factor subunit.	TATA-box binding protein like 1.	0.896
BRF1	TBPL2	ENSCPOP00000000059	ENSCPOP00000005547	BRF1 RNA polymerase III transcription initiation factor subunit.	TATA-box binding protein like 2.	0.985
C11orf88	BRF1	ENSCPOP00000028305	ENSCPOP00000000059	Chromosome 11 open reading frame 88.	BRF1 RNA polymerase III transcription initiation factor subunit.	0.896
C11orf88	DR1	ENSCPOP00000028305	ENSCPOP00000031753	Chromosome 11 open reading frame 88.	Down-regulator of transcription 1.	0.872
C11orf88	DRAP1	ENSCPOP00000028305	ENSCPOP00000020123	Chromosome 11 open reading frame 88.	DR1 associated protein 1.	0.890
C11orf88	ENSCPOP00000023083	ENSCPOP00000028305	ENSCPOP00000023083	Chromosome 11 open reading frame 88.	B-block_TFIIIC domain-containing protein.	0.584
C11orf88	GTF2A1	ENSCPOP00000028305	ENSCPOP00000003046	Chromosome 11 open reading frame 88.	General transcription factor IIA subunit 1.	0.890
C11orf88	GTF2A2	ENSCPOP00000028305	ENSCPOP00000029840	Chromosome 11 open reading frame 88.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.953