36 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Maged1	MAGE domain-containing protein. (778 aa)
	TMEM98	Transmembrane protein 98. (226 aa)
	SIRT1	Sirtuin 1. (717 aa)
	OTUD7B	OTU deubiquitinase 7B. (842 aa)
	DCLK3	Doublecortin like kinase 3. (645 aa)
	ANGPT1	Angiopoietin 1. (487 aa)
	LATS1	Large tumor suppressor kinase 1. (969 aa)
	APOD	Apolipoprotein D; APOD occurs in the macromolecular complex with lecithin- transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (189 aa)
	DCLK1	Doublecortin like kinase 1. (740 aa)
	TRIM29	Tripartite motif containing 29. (586 aa)
	SIN3A	SIN3 transcription regulator family member A. (1274 aa)
	NF1	Neurofibromin 1. (2750 aa)
	MFHAS1	Malignant fibrous histiocytoma amplified sequence 1. (952 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	EI24	EI24 autophagy associated transmembrane protein. (349 aa)
	ILRUN	Inflammation and lipid regulator with UBA-like and NBR1-like domains. (243 aa)
	FLCN	Folliculin. (579 aa)
	POLR1A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1711 aa)
	AKAP1	A-kinase anchoring protein 1. (860 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
	FERMT1	Fermitin family member 1. (676 aa)
	H0VV71_CAVPO	MAGE domain-containing protein. (689 aa)
	LATS2	Non-specific serine/threonine protein kinase. (955 aa)
	FBXO4	F-box protein 4. (324 aa)
	PKIG	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
	CLDN18	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
	CHP1	Calcineurin like EF-hand protein 1. (195 aa)
	RAB23	RAB23, member RAS oncogene family. (236 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	DCLK2	Doublecortin like kinase 2. (756 aa)
	LZTS2	Leucine zipper tumor suppressor 2. (668 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	UFM1	Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (85 aa)
	PKIA	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
	MDFIC	MyoD family inhibitor domain containing. (259 aa)
	Cabp1	Uncharacterized protein. (227 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHP1	DCLK1	ENSCPOP00000024538	ENSCPOP00000004527	Calcineurin like EF-hand protein 1.	Doublecortin like kinase 1.	0.521
CHP1	GSK3B	ENSCPOP00000024538	ENSCPOP00000012892	Calcineurin like EF-hand protein 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.529
Cabp1	DCLK1	ENSCPOP00000030092	ENSCPOP00000004527	Uncharacterized protein.	Doublecortin like kinase 1.	0.631
Cabp1	DCLK3	ENSCPOP00000030092	ENSCPOP00000002071	Uncharacterized protein.	Doublecortin like kinase 3.	0.412
DCLK1	CHP1	ENSCPOP00000004527	ENSCPOP00000024538	Doublecortin like kinase 1.	Calcineurin like EF-hand protein 1.	0.521
DCLK1	Cabp1	ENSCPOP00000004527	ENSCPOP00000030092	Doublecortin like kinase 1.	Uncharacterized protein.	0.631
DCLK3	Cabp1	ENSCPOP00000002071	ENSCPOP00000030092	Doublecortin like kinase 3.	Uncharacterized protein.	0.412
GSK3B	CHP1	ENSCPOP00000012892	ENSCPOP00000024538	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Calcineurin like EF-hand protein 1.	0.529
GSK3B	HNF4A	ENSCPOP00000012892	ENSCPOP00000006140	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Hepatocyte nuclear factor 4 alpha.	0.554
GSK3B	POLR1A	ENSCPOP00000012892	ENSCPOP00000011112	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.537
H0VV71_CAVPO	SUMO1	ENSCPOP00000014597	ENSCPOP00000027854	MAGE domain-containing protein.	Small ubiquitin-related modifier.	0.533
HNF4A	GSK3B	ENSCPOP00000006140	ENSCPOP00000012892	Hepatocyte nuclear factor 4 alpha.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.554
HNF4A	SIRT1	ENSCPOP00000006140	ENSCPOP00000000777	Hepatocyte nuclear factor 4 alpha.	Sirtuin 1.	0.445
LATS1	LATS2	ENSCPOP00000003231	ENSCPOP00000018190	Large tumor suppressor kinase 1.	Non-specific serine/threonine protein kinase.	0.937
LATS2	LATS1	ENSCPOP00000018190	ENSCPOP00000003231	Non-specific serine/threonine protein kinase.	Large tumor suppressor kinase 1.	0.937
Maged1	SUMO1	ENSCPOP00000003555	ENSCPOP00000027854	MAGE domain-containing protein.	Small ubiquitin-related modifier.	0.501
PKIA	PKIG	ENSCPOP00000028725	ENSCPOP00000024052	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	0.583
PKIG	PKIA	ENSCPOP00000024052	ENSCPOP00000028725	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.	0.583
POLR1A	GSK3B	ENSCPOP00000011112	ENSCPOP00000012892	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.537
SIN3A	SIRT1	ENSCPOP00000005437	ENSCPOP00000000777	SIN3 transcription regulator family member A.	Sirtuin 1.	0.588