STRINGSTRING
SDC1 SDC1 ABI3BP ABI3BP EHMT2 EHMT2 SNX30 SNX30 MPHOSPH9 MPHOSPH9 ATG5 ATG5 SDCBP SDCBP UBQLN2 UBQLN2 GRID2 GRID2 ASAP1 ASAP1 C10orf90 C10orf90 PAN2 PAN2 LRRTM2 LRRTM2 ENSCPOP00000030021 ENSCPOP00000030021 TBC1D7 TBC1D7 SIPA1L1 SIPA1L1 CAV3 CAV3 PAN3 PAN3 PLK1 PLK1 Wdr45 Wdr45 MSN MSN MNS1 MNS1 SDCCAG8 SDCCAG8 NUMA1 NUMA1 ATG2A ATG2A RAB3GAP2 RAB3GAP2 GSN GSN CHMP6 CHMP6 TBC1D30 TBC1D30 RBM14 RBM14 FSCN1 FSCN1 TBC1D12 TBC1D12 TAPT1 TAPT1 TMEM67 TMEM67 CROCC CROCC PIP4K2A PIP4K2A CDKL5 CDKL5 CDK5RAP2 CDK5RAP2 SCFD1 SCFD1 CNTROB CNTROB CEP76 CEP76 Gap43 Gap43 ATG3 ATG3 TMEM39B TMEM39B SMAD4 SMAD4 VPS11 VPS11 LRFN4 LRFN4 CEP192 CEP192 STYXL1 STYXL1 TRIM37 TRIM37 TRAPPC12 TRAPPC12 ARHGEF5 ARHGEF5 KIF15 KIF15 PIP4K2B PIP4K2B PRKAA1 PRKAA1 FUZ FUZ LOC100716676 LOC100716676 BECN1 BECN1 MTM1 MTM1 IL5 IL5 CCDC88A CCDC88A CNOT2 CNOT2 ODF2L ODF2L WRAP73 WRAP73 DYNC1H1 DYNC1H1 PTPRD PTPRD STIL STIL DCDC2 DCDC2 CHMP5 CHMP5 G3BP1 G3BP1 LOC106027361 LOC106027361 CHMP4C CHMP4C SNX7 SNX7 SH3GLB1 SH3GLB1 STX18 STX18 NUP62 NUP62 EZR EZR MFN2 MFN2 TBC1D14 TBC1D14 DYNC2LI1 DYNC2LI1 SASS6 SASS6 TESK1 TESK1 MAK MAK Chmp3 Chmp3 LCP1 LCP1 RABEP2 RABEP2 TNF TNF MTMR3 MTMR3 CHMP7 CHMP7 LIMK2 LIMK2 ZMYND10 ZMYND10 PATL2 PATL2 Spag5 Spag5 FEZ1 FEZ1 CEP135 CEP135 Pdcd6ip Pdcd6ip IFT140 IFT140 LRRC27 LRRC27 PINK1 PINK1 PIP4K2C PIP4K2C CCDC151 CCDC151 MDM1 MDM1 H0VWN2_CAVPO H0VWN2_CAVPO VDAC3 VDAC3 CNOT6L CNOT6L CYLD CYLD PRKAA2 PRKAA2 CHMP1A CHMP1A ADAMTS16 ADAMTS16 C9orf72 C9orf72 SMCR8 SMCR8 SNX4 SNX4 STAM STAM IFT88 IFT88 PLK2 PLK2 CSF2 CSF2 IL1RAP IL1RAP MCIDAS MCIDAS LRRTM1 LRRTM1 ATMIN ATMIN LOC100735003 LOC100735003 CCSAP CCSAP TPR TPR CEP120 CEP120 LOC100717205 LOC100717205 TMEM39A TMEM39A NPTXR NPTXR LRRC4B LRRC4B DRG1 DRG1 PQBP1 PQBP1 ENTR1 ENTR1 EML3 EML3 PHF23 PHF23 CBLN1 CBLN1 CEP295 CEP295 RAB3GAP1 RAB3GAP1 RDX RDX RNF5 RNF5 CEP97 CEP97 ALMS1 ALMS1 ARHGEF2 ARHGEF2 CDKL1 CDKL1 CHMP2B CHMP2B CROCC2 CROCC2 KIF9 KIF9 PIKFYVE PIKFYVE NUPR1 NUPR1 ARHGEF9 ARHGEF9 HTT HTT NTRK3 NTRK3 MAPK8 MAPK8 KAT2A KAT2A LRFN1 LRFN1 MAP4 MAP4 RALB RALB MAPK9 MAPK9 ENSCPOP00000025137 ENSCPOP00000025137 PLK4 PLK4 NOTO NOTO FEZ2 FEZ2 SENP6 SENP6 CHMP4B CHMP4B KCTD17 KCTD17 CNOT6 CNOT6 RNF4 RNF4 SYNE2 SYNE2 NUMB NUMB DNM2 DNM2 ENSCPOP00000026930 ENSCPOP00000026930 SDC4 SDC4 SEC22B SEC22B G3BP2 G3BP2 CHMP2A CHMP2A LRSAM1 LRSAM1 Syne1 Syne1 NPTX1 NPTX1 ENSCPOP00000027747 ENSCPOP00000027747 RAB1B RAB1B IFT20 IFT20 Spice1 Spice1 MAPK15 MAPK15 ARHGAP35 ARHGAP35 TTBK2 TTBK2 CNOT1 CNOT1 GSK3B GSK3B WIPI1 WIPI1 VPS4B VPS4B PTPRS PTPRS Tchp Tchp SEPTIN9 SEPTIN9 CENPJ CENPJ HNRNPU HNRNPU ULK1 ULK1 ENSCPOP00000028304 ENSCPOP00000028304 ENSCPOP00000028385 ENSCPOP00000028385 SNX18 SNX18 NBDY NBDY TSG101 TSG101 EVI5L EVI5L PPP1R35 PPP1R35 ENSCPOP00000028975 ENSCPOP00000028975 CDK10 CDK10 ARPC2 ARPC2 KIAA1324 KIAA1324
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (327 aa)
ABI3BPABI family member 3 binding protein. (1070 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1188 aa)
SNX30Sorting nexin family member 30. (493 aa)
MPHOSPH9M-phase phosphoprotein 9. (970 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
SDCBPSyndecan binding protein. (294 aa)
UBQLN2Ubiquilin 2. (624 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1147 aa)
C10orf90Chromosome 10 open reading frame 90. (700 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1204 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
ENSCPOP00000030021Uncharacterized protein; Belongs to the heat shock protein 70 family. (537 aa)
TBC1D7TBC1 domain family member 7. (293 aa)
SIPA1L1Signal induced proliferation associated 1 like 1. (1803 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (751 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
Wdr45Uncharacterized protein. (360 aa)
MSNMoesin. (577 aa)
MNS1Meiosis specific nuclear structural 1. (495 aa)
SDCCAG8Serologically defined colon cancer antigen 8. (714 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2117 aa)
ATG2AAutophagy related 2A. (1904 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1314 aa)
GSNGelsolin. (775 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
TBC1D30TBC1 domain family member 30. (720 aa)
RBM14RNA binding motif protein 14. (669 aa)
FSCN1Fascin. (493 aa)
TBC1D12TBC1 domain family member 12. (693 aa)
TAPT1Transmembrane anterior posterior transformation 1. (647 aa)
TMEM67Transmembrane protein 67. (1006 aa)
CROCCCiliary rootlet coiled-coil, rootletin. (2007 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa)
CDKL5Cyclin dependent kinase like 5. (947 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1868 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (664 aa)
CNTROBCentrobin, centriole duplication and spindle assembly protein. (908 aa)
CEP76Centrosomal protein 76. (627 aa)
Gap43Uncharacterized protein. (211 aa)
ATG3Autophagy-related protein 3. (317 aa)
TMEM39BTransmembrane protein 39B. (495 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (635 aa)
CEP192Centrosomal protein 192. (2495 aa)
STYXL1Serine/threonine/tyrosine interacting like 1. (317 aa)
TRIM37Tripartite motif containing 37. (926 aa)
TRAPPC12Trafficking protein particle complex 12. (797 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1597 aa)
KIF15Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1152 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (362 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
FUZFuzzy planar cell polarity protein. (392 aa)
LOC100716676TPR_REGION domain-containing protein. (567 aa)
BECN1Beclin 1. (448 aa)
MTM1Myotubularin 1. (599 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
CCDC88ACoiled-coil domain containing 88A. (1718 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (544 aa)
ODF2LOuter dense fiber of sperm tails 2 like. (549 aa)
WRAP73WD repeat containing, antisense to TP73. (462 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4637 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1767 aa)
STILSTIL centriolar assembly protein. (1049 aa)
DCDC2Doublecortin domain containing 2. (469 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
G3BP1G3BP stress granule assembly factor 1. (465 aa)
LOC106027361Uncharacterized protein. (1433 aa)
CHMP4CCharged multivesicular body protein 4C. (229 aa)
SNX7Sorting nexin 7. (470 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (394 aa)
STX18Syntaxin 18. (335 aa)
NUP62Nucleoporin 62. (518 aa)
EZREzrin. (586 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
TBC1D14TBC1 domain family member 14. (699 aa)
DYNC2LI1Dynein cytoplasmic 2 light intermediate chain 1. (351 aa)
SASS6SAS-6 centriolar assembly protein. (590 aa)
TESK1Testis associated actin remodelling kinase 1. (627 aa)
MAKMale germ cell associated kinase. (622 aa)
Chmp3Uncharacterized protein. (221 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
RABEP2Rabaptin, RAB GTPase binding effector protein 2. (562 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
MTMR3Myotubularin related protein 3. (1221 aa)
CHMP7Charged multivesicular body protein 7. (446 aa)
LIMK2LIM domain kinase 2. (637 aa)
ZMYND10Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (440 aa)
PATL2PAT1 homolog 2. (517 aa)
Spag5Sperm associated antigen 5. (1196 aa)
FEZ1Fasciculation and elongation protein zeta 1. (403 aa)
CEP135Centrosomal protein 135. (1140 aa)
Pdcd6ipBRO1 domain-containing protein. (872 aa)
IFT140Intraflagellar transport 140. (1463 aa)
LRRC27Leucine rich repeat containing 27. (508 aa)
PINK1PTEN induced kinase 1. (574 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (419 aa)
CCDC151Coiled-coil domain containing 151. (590 aa)
MDM1Mdm1 nuclear protein. (657 aa)
H0VWN2_CAVPOKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (676 aa)
VDAC3Voltage dependent anion channel 3. (283 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (462 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (932 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
SMCR8SMCR8-C9orf72 complex subunit. (936 aa)
SNX4Sorting nexin 4. (403 aa)
STAMSignal transducing adaptor molecule. (537 aa)
IFT88Intraflagellar transport 88. (825 aa)
PLK2Serine/threonine-protein kinase PLK. (682 aa)
CSF2Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (145 aa)
IL1RAPInterleukin 1 receptor accessory protein. (685 aa)
MCIDASMulticiliate differentiation and DNA synthesis associated cell cycle protein. (389 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
ATMINATM interactor. (588 aa)
LOC100735003Uncharacterized protein. (198 aa)
CCSAPCentriole, cilia and spindle associated protein. (247 aa)
TPRTranslocated promoter region, nuclear basket protein. (2320 aa)
CEP120Centrosomal protein 120. (952 aa)
LOC100717205Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
NPTXRNeuronal pentraxin receptor. (323 aa)
LRRC4BLeucine rich repeat containing 4B. (607 aa)
DRG1Developmentally regulated GTP binding protein 1. (367 aa)
PQBP1Polyglutamine binding protein 1. (265 aa)
ENTR1Endosome associated trafficking regulator 1. (429 aa)
EML3EMAP like 3. (881 aa)
PHF23PHD finger protein 23. (350 aa)
CBLN1Cerebellin 1 precursor. (105 aa)
CEP295Centrosomal protein 295. (2555 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (987 aa)
RDXRadixin. (604 aa)
RNF5Ring finger protein 5. (180 aa)
CEP97Centrosomal protein 97. (832 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (3698 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (986 aa)
CDKL1Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. (352 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
CROCC2Ciliary rootlet coiled-coil, rootletin family member 2. (1579 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (789 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2079 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (90 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (518 aa)
HTTHuntingtin. (3133 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
KAT2ALysine acetyltransferase 2A. (753 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (771 aa)
MAP4Microtubule-associated protein. (1128 aa)
RALBRAS like proto-oncogene B. (206 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSCPOP00000025137Uncharacterized protein. (279 aa)
PLK4Polo like kinase 4. (958 aa)
NOTONotochord homeobox. (210 aa)
FEZ2Fasciculation and elongation protein zeta 2. (318 aa)
SENP6SUMO specific peptidase 6. (1096 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
KCTD17Potassium channel tetramerization domain containing 17. (275 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (534 aa)
RNF4Ring finger protein 4. (190 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6922 aa)
NUMBNUMB endocytic adaptor protein. (648 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (878 aa)
ENSCPOP00000026930Uncharacterized protein. (339 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
G3BP2G3BP stress granule assembly factor 2. (482 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (727 aa)
Syne1KASH domain-containing protein. (952 aa)
NPTX1Neuronal pentraxin 1. (432 aa)
ENSCPOP00000027747LAM_G_DOMAIN domain-containing protein. (151 aa)
RAB1BRAB1B, member RAS oncogene family. (229 aa)
IFT20Intraflagellar transport 20. (132 aa)
Spice1Uncharacterized protein. (768 aa)
MAPK15Mitogen-activated protein kinase. (539 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
TTBK2Tau tubulin kinase 2. (1232 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2294 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1805 aa)
TchpUncharacterized protein. (500 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (674 aa)
CENPJCentromere protein J. (1340 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (822 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1037 aa)
ENSCPOP00000028304Uncharacterized protein. (64 aa)
ENSCPOP00000028385TPR_REGION domain-containing protein. (154 aa)
SNX18Sorting nexin. (607 aa)
NBDYNegative regulator of P-body association. (67 aa)
TSG101Tumor susceptibility 101. (391 aa)
EVI5LEcotropic viral integration site 5 like. (850 aa)
PPP1R35Protein phosphatase 1 regulatory subunit 35. (248 aa)
ENSCPOP00000028975Uncharacterized protein. (138 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (360 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
KIAA1324KIAA1324. (1014 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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