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CHD7 | Chromodomain helicase DNA binding protein 7. (2996 aa) | ||||
PCGF1 | Polycomb group ring finger 1. (259 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (799 aa) | ||||
GTF2F1 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (522 aa) | ||||
MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (504 aa) | ||||
PPARGC1A | PPARG coactivator 1 alpha. (796 aa) | ||||
SOX10 | SRY-box transcription factor 10. (469 aa) | ||||
ZNF683 | Zinc finger protein 683. (436 aa) | ||||
ZC3H4 | Zinc finger CCCH-type containing 4. (1218 aa) | ||||
LOC100718196 | Uncharacterized protein. (641 aa) | ||||
GLI2 | GLI family zinc finger 2. (1570 aa) | ||||
ENSCPOP00000025226 | Uncharacterized protein. (213 aa) | ||||
FOXO4 | Forkhead box O4. (505 aa) | ||||
IKZF3 | IKAROS family zinc finger 3. (510 aa) | ||||
DHX9 | DExH-box helicase 9. (1373 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa) | ||||
NRL | Leucine zipper transcription factor. (237 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1584 aa) | ||||
KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (865 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (300 aa) | ||||
GTF2B | General transcription factor IIB. (308 aa) | ||||
HSF1 | Heat shock transcription factor 1. (555 aa) | ||||
ESR2 | Estrogen receptor 2. (568 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa) | ||||
HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (822 aa) | ||||
E2F4 | E2F transcription factor 4. (411 aa) | ||||
TRIM33 | Tripartite motif containing 33. (1128 aa) | ||||
ZNF750 | Zinc finger protein 750. (703 aa) | ||||
H0VCZ7_CAVPO | Fork-head domain-containing protein. (548 aa) | ||||
NIPBL | Nipped-B protein. (2721 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) | ||||
MYBL1 | MYB proto-oncogene like 1. (749 aa) | ||||
DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) | ||||
RBL2 | RB transcriptional corepressor like 2. (1095 aa) | ||||
NUP98 | Nucleoporin 98. (1784 aa) | ||||
ISL1 | ISL LIM homeobox 1. (349 aa) | ||||
Trim28 | Uncharacterized protein. (829 aa) | ||||
TAF5 | TATA-box binding protein associated factor 5. (762 aa) | ||||
WDR13 | WD repeat domain 13. (485 aa) | ||||
H0V4A5_CAVPO | Uncharacterized protein. (830 aa) | ||||
ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) | ||||
EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (747 aa) | ||||
ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (781 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (504 aa) | ||||
ZNF609 | Zinc finger protein 609. (1409 aa) | ||||
SETDB1 | SET domain bifurcated histone lysine methyltransferase 1. (1290 aa) | ||||
RBL1 | RB transcriptional corepressor like 1. (1051 aa) | ||||
SIRT1 | Sirtuin 1. (717 aa) | ||||
MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa) | ||||
L3MBTL2 | L3MBTL histone methyl-lysine binding protein 2. (716 aa) | ||||
SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (737 aa) | ||||
IRF3 | Interferon regulatory factor 3. (389 aa) | ||||
Tro | MAGE domain-containing protein. (265 aa) | ||||
ATF4 | Activating transcription factor 4. (354 aa) | ||||
DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1600 aa) | ||||
PRDM15 | PR/SET domain 15. (1084 aa) | ||||
PCGF2 | Polycomb group ring finger 2. (342 aa) | ||||
FOXC2 | Forkhead box C2. (441 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (535 aa) | ||||
MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (318 aa) | ||||
NFE2L1 | Nuclear factor, erythroid 2 like 1. (743 aa) | ||||
ENSCPOP00000021738 | RING-type domain-containing protein. (326 aa) | ||||
POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1833 aa) | ||||
EHMT2 | Euchromatic histone lysine methyltransferase 2. (1188 aa) | ||||
HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) | ||||
PRDM1 | PR/SET domain 1. (813 aa) | ||||
POU4F2 | POU domain protein. (408 aa) | ||||
HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1078 aa) |