STRINGSTRING
MYC MYC TP63 TP63 KDM2B KDM2B TEAD3 TEAD3 LBH LBH BMP7 BMP7 BCL7B BCL7B SAV1 SAV1 PAX8 PAX8 ESRRB ESRRB NCOA3 NCOA3 ZC3H13 ZC3H13 ENSCPOP00000030875 ENSCPOP00000030875 BICRAL BICRAL CNOT2 CNOT2 TAF6L TAF6L HNF1B HNF1B ZNF322 ZNF322 PTN PTN WNT9B WNT9B LOXL2 LOXL2 WDR43 WDR43 ELAVL1 ELAVL1 CNOT1 CNOT1 SMO SMO H0VN16_CAVPO H0VN16_CAVPO H0VQ66_CAVPO H0VQ66_CAVPO TCF7L1 TCF7L1 TAF5L TAF5L PRDM14 PRDM14 TEAD4 TEAD4 KDM3A KDM3A PAX2 PAX2 ENSCPOP00000022509 ENSCPOP00000022509 ZNF706 ZNF706 CNOT3 CNOT3 KAT2A KAT2A BCL7A BCL7A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
KDM2BLysine demethylase 2B. (1306 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (456 aa)
LBHProtein LBH; Transcriptional activator; Belongs to the LBH family. (105 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
BCL7BBAF chromatin remodeling complex subunit BCL7B. (202 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
PAX8Paired box 8. (457 aa)
ESRRBEstrogen related receptor beta. (454 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
ZC3H13Zinc finger CCCH-type containing 13. (1645 aa)
ENSCPOP00000030875ARID domain-containing protein. (504 aa)
BICRALBRD4 interacting chromatin remodeling complex associated protein like. (1074 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (544 aa)
TAF6LTATA-box binding protein associated factor 6 like. (588 aa)
HNF1BHNF1 homeobox B. (558 aa)
ZNF322Zinc finger protein 322. (398 aa)
PTNPleiotrophin. (168 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LOXL2Lysyl oxidase like 2. (779 aa)
WDR43WD repeat domain 43. (654 aa)
ELAVL1ELAV like RNA binding protein 1. (295 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2294 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
H0VN16_CAVPOUncharacterized protein. (71 aa)
H0VQ66_CAVPOUncharacterized protein. (336 aa)
TCF7L1Transcription factor 7 like 1. (587 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
PRDM14PR/SET domain 14. (515 aa)
TEAD4Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (450 aa)
KDM3ALysine demethylase 3A. (1258 aa)
PAX2Paired box 2. (393 aa)
ENSCPOP00000022509Uncharacterized protein. (140 aa)
ZNF706Zinc finger protein 706. (76 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (751 aa)
KAT2ALysine acetyltransferase 2A. (753 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (188 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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