STRINGSTRING
RAB3GAP1 RAB3GAP1 LOC100713271 LOC100713271 ADORA2B ADORA2B ATP2A2 ATP2A2 PRKCG PRKCG SYP SYP ENSCPOP00000028762 ENSCPOP00000028762 RAB3A RAB3A Chrna7 Chrna7 CYTH1 CYTH1 P2RX1 P2RX1 PFN2 PFN2 NRN1 NRN1 SNAPIN SNAPIN Chrnb2 Chrnb2 ENSCPOP00000030659 ENSCPOP00000030659 HTR1A HTR1A GIT2 GIT2 BRAF BRAF Ncs1 Ncs1 NR3C2 NR3C2 Rap1b Rap1b CDK5 CDK5 NRXN3 NRXN3 RAP1A RAP1A BCL2L1 BCL2L1 GIPC2 GIPC2 RIMS3 RIMS3 SYT1 SYT1 APBA2 APBA2 ADCY1 ADCY1 KCNH1 KCNH1 PRKCB PRKCB PPFIA2 PPFIA2 FMR1 FMR1 CACNA1B CACNA1B RAB5A RAB5A GIT1 GIT1 Cacnb2 Cacnb2 GRIN3A GRIN3A DVL1 DVL1 STXBP5L STXBP5L ERC1 ERC1 DRD2 DRD2 DTNBP1 DTNBP1 PREPL PREPL CHRNA6 CHRNA6 SYT4 SYT4 CSPG5 CSPG5 Cacnb4 Cacnb4 DRD1 DRD1 APBA1 APBA1 MYO6 MYO6 CHRNA4 CHRNA4 RIMS4 RIMS4 CASK CASK CHRNB3 CHRNB3 GLRA3 GLRA3 P2RY2 P2RY2 CHRNA5 CHRNA5 CHRNA3 CHRNA3 BACE1 BACE1 SYNPR SYNPR STXBP5 STXBP5 LOC100730761 LOC100730761 GSK3B GSK3B FBXL20 FBXL20 CHRM2 CHRM2 PRKCA PRKCA DNM1L DNM1L SLC4A8 SLC4A8 PRKCE PRKCE H0VX85_CAVPO H0VX85_CAVPO VPS18 VPS18 GRM7 GRM7 NLGN1 NLGN1 GIPC3 GIPC3 GIPC1 GIPC1 H0WA79_CAVPO H0WA79_CAVPO CNR1 CNR1 Drd4 Drd4 DGKI DGKI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (987 aa)
LOC100713271Uncharacterized protein. (165 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (221 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
SYPSynaptophysin. (312 aa)
ENSCPOP00000028762Uncharacterized protein. (107 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
Chrna7Uncharacterized protein. (483 aa)
CYTH1Cytohesin 1. (400 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
PFN2Profilin; Belongs to the profilin family. (140 aa)
NRN1Neuritin 1. (142 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
Chrnb2Uncharacterized protein. (499 aa)
ENSCPOP00000030659G_PROTEIN_RECEP_F3_4 domain-containing protein. (497 aa)
HTR1A5-hydroxytryptamine receptor 1A. (421 aa)
GIT2GIT ArfGAP 2. (759 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (738 aa)
Ncs1Uncharacterized protein. (168 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (1010 aa)
Rap1bUncharacterized protein. (184 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
NRXN3Neurexin 3. (1571 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
BCL2L1BCL2 like 1. (233 aa)
GIPC2GIPC PDZ domain containing family member 2. (252 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
SYT1Synaptotagmin 1. (422 aa)
APBA2Amyloid beta precursor protein binding family A member 2. (750 aa)
ADCY1Adenylate cyclase 1. (944 aa)
KCNH1Uncharacterized protein. (989 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa)
PPFIA2PTPRF interacting protein alpha 2. (1165 aa)
FMR1Fragile X mental retardation 1. (612 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2270 aa)
RAB5ARAB5A, member RAS oncogene family. (214 aa)
GIT1GIT ArfGAP 1. (757 aa)
Cacnb2SH3 domain-containing protein. (621 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1114 aa)
DVL1Dishevelled segment polarity protein 1. (698 aa)
STXBP5LSyntaxin binding protein 5 like. (1098 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1116 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
DTNBP1Dystrobrevin binding protein 1. (354 aa)
PREPLProlyl endopeptidase like. (727 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
SYT4Synaptotagmin 4. (425 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (521 aa)
Cacnb4SH3 domain-containing protein. (519 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (444 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (837 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (620 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (253 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (463 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (376 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (438 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (506 aa)
BACE1Beta-secretase 1; Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (By similarity). Cleaves CHL1 (By similarity); Belongs to the peptidase A1 family. (498 aa)
SYNPRSynaptoporin. (285 aa)
STXBP5Syntaxin binding protein 5. (1067 aa)
LOC100730761Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
FBXL20F-box and leucine rich repeat protein 20. (436 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
SLC4A8Anion exchange protein. (1090 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
H0VX85_CAVPOUncharacterized protein. (184 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (974 aa)
GRM7Glutamate metabotropic receptor 7. (922 aa)
NLGN1Neuroligin 1. (843 aa)
GIPC3GIPC PDZ domain containing family member 3. (294 aa)
GIPC1GIPC PDZ domain containing family member 1. (332 aa)
H0WA79_CAVPOANF_receptor domain-containing protein. (187 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
Drd4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa)
DGKIDiacylglycerol kinase. (957 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (30%) [HD]