67 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNB1	Beta-transducin. (340 aa)
	CDHR1	Cadherin related family member 1. (857 aa)
	RHO	Rhodopsin. (348 aa)
	PCARE	Photoreceptor cilium actin regulator. (1170 aa)
	Lyar	Uncharacterized protein. (191 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (507 aa)
	PDE6B	Phosphodiesterase. (854 aa)
	Cfap410	Uncharacterized protein. (257 aa)
	CNGA3	Cyclic nucleotide gated channel subunit alpha 3. (647 aa)
	Rpgr	Uncharacterized protein. (645 aa)
	PDE6G	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones (By similarity). (87 aa)
	PDE6H	Phosphodiesterase 6H. (83 aa)
	IFT140	Intraflagellar transport 140. (1463 aa)
	PDE6A	Phosphodiesterase. (860 aa)
	MAK	Male germ cell associated kinase. (622 aa)
	DHRS3	Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
	GUCY2D	Guanylate cyclase. (1102 aa)
	USH1C	USH1 protein network component harmonin. (909 aa)
	BBS7	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
	MYRIP	Myosin VIIA and Rab interacting protein. (830 aa)
	LOC100735737	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (209 aa)
	PDC	Phosducin. (245 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
	ENSCPOP00000023932	Uncharacterized protein. (332 aa)
	IQCB1	IQ motif containing B1. (598 aa)
	MYO7A	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2203 aa)
	PRPH2	Peripherin 2. (346 aa)
	MAP1A	Microtubule associated protein 1A. (2915 aa)
	RAB27A	RAB27A, member RAS oncogene family. (220 aa)
	PCDH15	Protocadherin related 15. (1913 aa)
	MYO3B	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1306 aa)
	ENSCPOP00000030527	Uncharacterized protein. (111 aa)
	TMEM237	Transmembrane protein 237. (399 aa)
	ENSCPOP00000029356	Uncharacterized protein. (1121 aa)
	CEP290	Centrosomal protein 290. (2425 aa)
	STX3	Syntaxin 3; Belongs to the syntaxin family. (288 aa)
	PRCD	Photoreceptor disc component. (58 aa)
	ENSCPOP00000025512	Uncharacterized protein. (230 aa)
	ENSCPOP00000025137	Uncharacterized protein. (279 aa)
	MYO5A	Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
	RD3	Retinal degeneration 3, GUCY2D regulator. (159 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1237 aa)
	ABCA4	ATP binding cassette subfamily A member 4. (2270 aa)
	Guca1a	Uncharacterized protein. (200 aa)
	ROM1	Retinal outer segment membrane protein 1. (351 aa)
	NUP42	Nucleoporin 42. (416 aa)
	H0VQQ2_CAVPO	Cyclic nucleotide-binding domain-containing protein. (852 aa)
	SAG	S-antigen. (404 aa)
	GRK1	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
	GRK7	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (550 aa)
	CNGB3	Cyclic nucleotide gated channel subunit beta 3. (667 aa)
	Gnat2	Uncharacterized protein. (354 aa)
	PTPRK	Protein tyrosine phosphatase receptor type K. (1455 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (989 aa)
	SLC24A4	Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (605 aa)
	H0VFY3_CAVPO	Uncharacterized protein. (674 aa)
	GUCA1B	Guanylate cyclase activator 1B. (200 aa)
	H0VER4_CAVPO	DAGKc domain-containing protein. (277 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNAT1	Alpha-transducin. (350 aa)
	PTGS1	Prostaglandin-endoperoxide synthase 1. (553 aa)
	HNF1A	HNF1 homeobox A. (628 aa)
	PPEF2	Serine/threonine-protein phosphatase with EF-hands. (733 aa)
	SPATA7	Spermatogenesis associated 7. (588 aa)
	PPEF1	Serine/threonine-protein phosphatase with EF-hands. (647 aa)
	GUCY2F	Guanylate cyclase. (1109 aa)
	MAP1B	Microtubule associated protein 1B. (2465 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA4	CDHR1	ENSCPOP00000013942	ENSCPOP00000004705	ATP binding cassette subfamily A member 4.	Cadherin related family member 1.	0.402
ABCA4	CNGB3	ENSCPOP00000013942	ENSCPOP00000011652	ATP binding cassette subfamily A member 4.	Cyclic nucleotide gated channel subunit beta 3.	0.639
ABCA4	Gnat2	ENSCPOP00000013942	ENSCPOP00000010358	ATP binding cassette subfamily A member 4.	Uncharacterized protein.	0.403
ABCA4	H0VER4_CAVPO	ENSCPOP00000013942	ENSCPOP00000008521	ATP binding cassette subfamily A member 4.	DAGKc domain-containing protein.	0.423
ABCA4	H0VQQ2_CAVPO	ENSCPOP00000013942	ENSCPOP00000012882	ATP binding cassette subfamily A member 4.	Cyclic nucleotide-binding domain-containing protein.	0.425
ABCA4	PRPH2	ENSCPOP00000013942	ENSCPOP00000020574	ATP binding cassette subfamily A member 4.	Peripherin 2.	0.689
ABCA4	RHO	ENSCPOP00000013942	ENSCPOP00000004486	ATP binding cassette subfamily A member 4.	Rhodopsin.	0.469
ABCA4	ROM1	ENSCPOP00000013942	ENSCPOP00000015288	ATP binding cassette subfamily A member 4.	Retinal outer segment membrane protein 1.	0.526
ABCA4	Rpgr	ENSCPOP00000013942	ENSCPOP00000017965	ATP binding cassette subfamily A member 4.	Uncharacterized protein.	0.628
BBS7	CEP290	ENSCPOP00000001110	ENSCPOP00000032712	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Centrosomal protein 290.	0.535
BBS7	IFT140	ENSCPOP00000001110	ENSCPOP00000002994	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Intraflagellar transport 140.	0.622
BBS7	PDE6A	ENSCPOP00000001110	ENSCPOP00000001770	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Phosphodiesterase.	0.454
BBS7	PDE6B	ENSCPOP00000001110	ENSCPOP00000017263	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Phosphodiesterase.	0.454
CDHR1	ABCA4	ENSCPOP00000004705	ENSCPOP00000013942	Cadherin related family member 1.	ATP binding cassette subfamily A member 4.	0.402
CDHR1	H0VER4_CAVPO	ENSCPOP00000004705	ENSCPOP00000008521	Cadherin related family member 1.	DAGKc domain-containing protein.	0.412
CDHR1	PCDH15	ENSCPOP00000004705	ENSCPOP00000031663	Cadherin related family member 1.	Protocadherin related 15.	0.652
CDHR1	PRPH2	ENSCPOP00000004705	ENSCPOP00000020574	Cadherin related family member 1.	Peripherin 2.	0.435
CDHR1	USH1C	ENSCPOP00000004705	ENSCPOP00000001142	Cadherin related family member 1.	USH1 protein network component harmonin.	0.722
CEP290	BBS7	ENSCPOP00000032712	ENSCPOP00000001110	Centrosomal protein 290.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.535
CEP290	IFT140	ENSCPOP00000032712	ENSCPOP00000002994	Centrosomal protein 290.	Intraflagellar transport 140.	0.649