STRINGSTRING
RPS13 RPS13 MIDN MIDN Zcchc17 Zcchc17 FGF22 FGF22 GNL3 GNL3 BMS1 BMS1 SIRT1 SIRT1 NCL NCL UTP18 UTP18 Rdm1 Rdm1 POLR2E POLR2E C15orf40 C15orf40 SIRT7 SIRT7 DDX27 DDX27 DDX50 DDX50 TAF1D TAF1D TCOF1 TCOF1 POP1 POP1 WRN WRN POP4 POP4 UTP20 UTP20 DDX56 DDX56 Pes1 Pes1 GTPBP10 GTPBP10 RPAIN RPAIN RRN3 RRN3 Lyar Lyar UTP25 UTP25 RRP12 RRP12 RRH RRH BYSL BYSL EXOSC8 EXOSC8 NEPRO NEPRO NOLC1 NOLC1 Senp3 Senp3 Hjurp Hjurp EBNA1BP2 EBNA1BP2 BOP1 BOP1 POP7 POP7 ILF2 ILF2 DDX24 DDX24 NMD3 NMD3 UTP4 UTP4 AATF AATF RPP21 RPP21 LIN28B LIN28B RBM28 RBM28 NPM3 NPM3 BAZ2A BAZ2A H0V8D3_CAVPO H0V8D3_CAVPO URB1 URB1 RPF2 RPF2 APEX2 APEX2 DDX18 DDX18 NOL10 NOL10 HERC4 HERC4 NSUN2 NSUN2 HEATR1 HEATR1 Sdad1 Sdad1 Pum3 Pum3 WDR12 WDR12 DKC1 DKC1 CARF CARF H0VDD3_CAVPO H0VDD3_CAVPO REXO5 REXO5 TOP1 TOP1 WDR55 WDR55 Plk5 Plk5 RAI14 RAI14 RTF1 RTF1 RSL24D1 RSL24D1 AKAP8 AKAP8 RPS7 RPS7 OTP OTP POLR1E POLR1E RPL3 RPL3 USP36 USP36 Sp140 Sp140 HUNK HUNK RSL1D1 RSL1D1 CTCF CTCF TAF1C TAF1C TAF1B TAF1B WDR43 WDR43 ATM ATM Ccr2 Ccr2 MCRS1 MCRS1 FTSJ3 FTSJ3 NOL11 NOL11 ZCCHC4 ZCCHC4 BAZ1B BAZ1B SPTY2D1 SPTY2D1 RPL26L1 RPL26L1 NOL6 NOL6 POP5 POP5 POLR1A POLR1A RRP8 RRP8 CCDC137 CCDC137 MRI1 MRI1 RPS25 RPS25 WDR75 WDR75 MPHOSPH10 MPHOSPH10 RRP9 RRP9 PRKDC PRKDC MYBBP1A MYBBP1A DCLRE1A DCLRE1A UTP6 UTP6 Pa2g4 Pa2g4 FHIT FHIT NOP56 NOP56 RCL1 RCL1 DDX21 DDX21 SMARCA4 SMARCA4 MDN1 MDN1 Parp1 Parp1 NOP53 NOP53 POLR1B POLR1B RGS22 RGS22 Urb2 Urb2 Pwp2 Pwp2 Lin28a Lin28a Cebpa Cebpa ADARB1 ADARB1 H0W0R6_CAVPO H0W0R6_CAVPO H0W0Z6_CAVPO H0W0Z6_CAVPO RPS9 RPS9 LOC100718426 LOC100718426 NSUN5 NSUN5 H0W359_CAVPO H0W359_CAVPO OXR1 OXR1 CLEC3B CLEC3B NOL9 NOL9 PAK6 PAK6 RPS14 RPS14 PES1 PES1 METTL18 METTL18 PARP2 PARP2 H0W708_CAVPO H0W708_CAVPO H0W794_CAVPO H0W794_CAVPO IMP4 IMP4 Vhl Vhl Nop2 Nop2 LOC100723124 LOC100723124 Pou5f1 Pou5f1 GNL2 GNL2 RRS1 RRS1 HMOX1 HMOX1 LDOC1 LDOC1 HIRIP3 HIRIP3 H1-10 H1-10 HDHD3 HDHD3 IMP3 IMP3 LOC100721370 LOC100721370 SELENBP1 SELENBP1 SPATA24 SPATA24 MDM2 MDM2 Sp100 Sp100 PUS1 PUS1 NOP58 NOP58 PARN PARN SPRN SPRN RRP7A RRP7A KAT5 KAT5 RRP1 RRP1 XPO1 XPO1 UTP15 UTP15 STK35 STK35 RPL11 RPL11 Ypel1 Ypel1 PHF8 PHF8 DEDD DEDD RRP1B RRP1B NOP10 NOP10 SURF6 SURF6 SPATA2 SPATA2 Eif3l Eif3l YPEL3 YPEL3 FBL FBL EWSR1 EWSR1 ENSCPOP00000024428 ENSCPOP00000024428 WDR36 WDR36 EXOSC9 EXOSC9 RBIS RBIS TAF1A TAF1A WDR3 WDR3 ENSCPOP00000024689 ENSCPOP00000024689 CDKN2AIP CDKN2AIP RREB1 RREB1 MYC MYC SNU13 SNU13 RBM4B RBM4B PES1-2 PES1-2 ACIN1 ACIN1 ENSCPOP00000026034 ENSCPOP00000026034 ENSCPOP00000026253 ENSCPOP00000026253 RPL26 RPL26 CD3EAP CD3EAP RPL5 RPL5 POLR1C POLR1C GAR1 GAR1 ZBED6 ZBED6 ZNF346 ZNF346 DDX47 DDX47 Syne1 Syne1 POLR2H POLR2H PRKRIP1 PRKRIP1 JMJD6 JMJD6 MAP3K14 MAP3K14 SBDS SBDS ENSCPOP00000028553 ENSCPOP00000028553 ELOF1 ELOF1 MDFIC MDFIC DHX9 DHX9 APTX APTX AOPEP AOPEP RPP30 RPP30 TP53 TP53 GGN GGN DDX55 DDX55 POLR2F POLR2F WDR46 WDR46 RERG RERG SRSF9 SRSF9 LLPH LLPH POLI POLI TMA16 TMA16 PWP1 PWP1 ENSCPOP00000030583 ENSCPOP00000030583 CHCHD1 CHCHD1 Smn1 Smn1 ENSCPOP00000030866 ENSCPOP00000030866 VDR VDR YPEL2 YPEL2 NSUN7 NSUN7 TOP2B TOP2B ERCC6 ERCC6 ENSCPOP00000031613 ENSCPOP00000031613 RBM19 RBM19 ENSCPOP00000031793 ENSCPOP00000031793 ENSCPOP00000031848 ENSCPOP00000031848 LOC106027361 LOC106027361 DEK DEK LOC100718706 LOC100718706 Nol12 Nol12 SMUG1 SMUG1 RIOX1 RIOX1 ENSCPOP00000032877 ENSCPOP00000032877 YPEL4 YPEL4 ETV6 ETV6 RASL11A RASL11A RPS10-NUDT3 RPS10-NUDT3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RPS13Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (132 aa)
MIDNMidnolin. (470 aa)
Zcchc17Uncharacterized protein. (241 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (160 aa)
GNL3G protein nucleolar 3. (518 aa)
BMS1BMS1 ribosome biogenesis factor. (1277 aa)
SIRT1Sirtuin 1. (717 aa)
NCLNucleolin. (713 aa)
UTP18UTP18 small subunit processome component. (540 aa)
Rdm1RRM domain-containing protein. (287 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
C15orf40Chromosome 15 open reading frame 40. (126 aa)
SIRT7Sirtuin 7. (401 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (765 aa)
DDX50DExD-box helicase 50. (735 aa)
TAF1DTATA-box binding protein associated factor, RNA polymerase I subunit D. (267 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1601 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1012 aa)
WRNWRN RecQ like helicase. (1462 aa)
POP4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (220 aa)
UTP20UTP20 small subunit processome component. (2752 aa)
DDX56DEAD-box helicase 56. (547 aa)
Pes1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (590 aa)
GTPBP10GTP binding protein 10. (367 aa)
RPAINRPA interacting protein. (209 aa)
RRN3RRN3 homolog, RNA polymerase I transcription factor. (658 aa)
LyarUncharacterized protein. (191 aa)
UTP25UTP25 small subunit processor component. (690 aa)
RRP12Ribosomal RNA processing 12 homolog. (1291 aa)
RRHRetinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family. (337 aa)
BYSLBystin like. (436 aa)
EXOSC8Exosome component 8. (276 aa)
NEPRONucleolus and neural progenitor protein. (563 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (732 aa)
Senp3ULP_PROTEASE domain-containing protein. (572 aa)
HjurpUncharacterized protein. (696 aa)
EBNA1BP2EBNA1 binding protein 2. (305 aa)
BOP1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (734 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
ILF2Interleukin enhancer binding factor 2. (390 aa)
DDX24DEAD-box helicase 24. (841 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (465 aa)
UTP4UTP4 small subunit processome component. (686 aa)
AATFApoptosis antagonizing transcription factor. (568 aa)
RPP21Ribonuclease P/MRP subunit p21. (161 aa)
LIN28BLin-28 homolog B. (250 aa)
RBM28RNA binding motif protein 28. (758 aa)
NPM3Nucleophosmin/nucleoplasmin 3. (170 aa)
BAZ2ABromodomain adjacent to zinc finger domain 2A. (1791 aa)
H0V8D3_CAVPOUncharacterized protein. (99 aa)
URB1URB1 ribosome biogenesis homolog. (2253 aa)
RPF2Ribosome production factor 2 homolog. (306 aa)
APEX2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (514 aa)
DDX18RNA helicase. (656 aa)
NOL10Nucleolar protein 10. (688 aa)
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1030 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (765 aa)
HEATR1HEAT repeat containing 1. (2142 aa)
Sdad1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (678 aa)
Pum3PUM-HD domain-containing protein. (648 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
DKC1Dyskerin pseudouridine synthase 1. (513 aa)
CARFCalcium responsive transcription factor. (722 aa)
H0VDD3_CAVPOHomeobox domain-containing protein. (286 aa)
REXO5RNA exonuclease 5. (814 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (768 aa)
WDR55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (380 aa)
Plk5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (460 aa)
RAI14Retinoic acid induced 14. (980 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (732 aa)
RSL24D1Ribosomal L24 domain containing 1. (163 aa)
AKAP8A-kinase anchoring protein 8; Belongs to the AKAP95 family. (670 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
OTPOrthopedia homeobox. (325 aa)
POLR1ERNA polymerase I subunit E. (418 aa)
RPL3Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (403 aa)
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1102 aa)
Sp140Uncharacterized protein. (693 aa)
HUNKHormonally up-regulated Neu-associated kinase. (648 aa)
RSL1D1Ribosomal L1 domain containing 1. (468 aa)
CTCFCCCTC-binding factor. (711 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (837 aa)
TAF1BTATA-box binding protein associated factor, RNA polymerase I subunit B. (635 aa)
WDR43WD repeat domain 43. (654 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3031 aa)
Ccr2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (371 aa)
MCRS1Microspherule protein 1. (462 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (838 aa)
NOL11Nucleolar protein 11. (707 aa)
ZCCHC4Zinc finger CCHC-type containing 4. (518 aa)
BAZ1BBromodomain adjacent to zinc finger domain 1B. (1438 aa)
SPTY2D1SPT2 chromatin protein domain containing 1. (691 aa)
RPL26L1Ribosomal protein L26 like 1. (136 aa)
NOL6Nucleolar protein 6. (1146 aa)
POP5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (168 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1711 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (457 aa)
CCDC137Coiled-coil domain containing 137. (282 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (362 aa)
RPS2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa)
WDR75WD repeat domain 75. (848 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (681 aa)
RRP9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (472 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4043 aa)
MYBBP1AMYB binding protein 1a. (1339 aa)
DCLRE1ADNA cross-link repair 1A. (913 aa)
UTP6UTP6 small subunit processome component. (596 aa)
Pa2g4Peptidase_M24 domain-containing protein. (394 aa)
FHITBis(5'-adenosyl)-triphosphatase. (150 aa)
NOP56NOP56 ribonucleoprotein. (592 aa)
RCL1RNA terminal phosphate cyclase like 1. (373 aa)
DDX21DExD-box helicase 21. (797 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1636 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5563 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (476 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1135 aa)
RGS22Regulator of G protein signaling 22. (1187 aa)
Urb2Urb2 domain-containing protein. (968 aa)
Pwp2Uncharacterized protein. (924 aa)
Lin28aCCHC-type domain-containing protein. (147 aa)
CebpaUncharacterized protein. (158 aa)
ADARB1Adenosine deaminase RNA specific B1. (603 aa)
H0W0R6_CAVPOUncharacterized protein. (958 aa)
H0W0Z6_CAVPODUF4939 domain-containing protein. (113 aa)
RPS9Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
LOC100718426Uncharacterized protein. (152 aa)
NSUN5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (461 aa)
H0W359_CAVPO40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (159 aa)
OXR1Oxidation resistance 1. (868 aa)
CLEC3BC-type lectin domain family 3 member B. (201 aa)
NOL9Nucleolar protein 9. (724 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
RPS14Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (549 aa)
METTL18Methyltransferase like 18. (373 aa)
PARP2Poly [ADP-ribose] polymerase. (536 aa)
H0W708_CAVPOUncharacterized protein. (206 aa)
H0W794_CAVPODUF4939 domain-containing protein. (110 aa)
IMP4IMP U3 small nucleolar ribonucleoprotein 4. (210 aa)
VhlUncharacterized protein. (182 aa)
Nop2SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (787 aa)
LOC100723124CCHC-type domain-containing protein. (209 aa)
Pou5f1POU domain protein. (361 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (708 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (357 aa)
HMOX1Heme oxygenase 1. (297 aa)
LDOC1LDOC1 regulator of NFKB signaling. (145 aa)
HIRIP3HIRA interacting protein 3. (567 aa)
H1-10H1 histone family member X. (185 aa)
HDHD3Haloacid dehalogenase like hydrolase domain containing 3. (249 aa)
IMP3IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)
LOC100721370Uncharacterized protein. (258 aa)
SELENBP1Selenium binding protein 1. (471 aa)
SPATA24Spermatogenesis associated 24. (205 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
Sp100Uncharacterized protein. (829 aa)
PUS1Pseudouridine synthase 1. (425 aa)
NOP58NOP58 ribonucleoprotein. (512 aa)
PARNPoly(A)-specific ribonuclease. (637 aa)
SPRNShadow of prion protein. (151 aa)
RRP7ARibosomal RNA processing 7 homolog A. (280 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa)
RRP1Ribosomal RNA processing 1. (448 aa)
XPO1Exportin 1. (1062 aa)
UTP15UTP15 small subunit processome component. (517 aa)
STK35Serine/threonine kinase 35. (539 aa)
RPL11Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
Ypel1Protein yippee-like; Belongs to the yippee family. (119 aa)
PHF8PHD finger protein 8. (1021 aa)
DEDDDeath effector domain containing. (318 aa)
RRP1BRibosomal RNA processing 1B. (719 aa)
NOP10NOP10 ribonucleoprotein. (64 aa)
SURF6Surfeit 6. (358 aa)
SPATA2Spermatogenesis associated 2. (513 aa)
Eif3lEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (607 aa)
YPEL3Protein yippee-like; Belongs to the yippee family. (119 aa)
FBLFibrillarin. (320 aa)
EWSR1EWS RNA binding protein 1. (653 aa)
ENSCPOP00000024428PARP-type domain-containing protein. (104 aa)
WDR36WD repeat domain 36. (909 aa)
EXOSC9Exosome component 9. (439 aa)
RBISRibosomal biogenesis factor. (100 aa)
TAF1ATATA-box binding protein associated factor, RNA polymerase I subunit A. (450 aa)
WDR3WD repeat domain 3. (943 aa)
ENSCPOP00000024689Uncharacterized protein. (120 aa)
CDKN2AIPCDKN2A interacting protein. (565 aa)
RREB1Ras responsive element binding protein 1. (1738 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
RBM4BRNA binding motif protein 4B. (358 aa)
PES1-2Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (563 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1327 aa)
ENSCPOP00000026034Tudor domain-containing protein. (290 aa)
ENSCPOP00000026253Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (565 aa)
RPL26Ribosomal protein L26. (145 aa)
CD3EAPCD3e molecule associated protein. (518 aa)
RPL5Ribosomal_L18_c domain-containing protein. (297 aa)
POLR1CRNA polymerase I and III subunit C. (346 aa)
GAR1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (222 aa)
ZBED6Zinc finger BED-type containing 6. (979 aa)
ZNF346Zinc finger protein 346. (294 aa)
DDX47DEAD-box helicase 47; Belongs to the DEAD box helicase family. (455 aa)
Syne1KASH domain-containing protein. (952 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
PRKRIP1PRKR interacting protein 1. (186 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (937 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
ENSCPOP00000028553Fcf2 domain-containing protein. (109 aa)
ELOF1Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (83 aa)
MDFICMyoD family inhibitor domain containing. (259 aa)
DHX9DExH-box helicase 9. (1373 aa)
APTXAprataxin. (341 aa)
AOPEPAminopeptidase O (putative). (723 aa)
RPP30Ribonuclease P/MRP subunit p30. (268 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa)
GGNGametogenetin. (713 aa)
DDX55RNA helicase. (628 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
WDR46WD repeat domain 46. (625 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
SRSF9Serine and arginine rich splicing factor 9. (221 aa)
LLPHLLP homolog, long-term synaptic facilitation factor. (128 aa)
POLIDNA polymerase iota. (662 aa)
TMA16Translation machinery associated 16 homolog. (204 aa)
PWP1PWP1 homolog, endonuclein. (500 aa)
ENSCPOP00000030583RRM domain-containing protein. (94 aa)
CHCHD1Coiled-coil-helix-coiled-coil-helix domain containing 1. (118 aa)
Smn1Tudor domain-containing protein. (302 aa)
ENSCPOP00000030866ANK_REP_REGION domain-containing protein. (133 aa)
VDRVitamin D receptor. (424 aa)
YPEL2Protein yippee-like; Belongs to the yippee family. (119 aa)
NSUN7NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (688 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1614 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1473 aa)
ENSCPOP00000031613S10_plectin domain-containing protein. (151 aa)
RBM19RNA binding motif protein 19. (961 aa)
ENSCPOP00000031793Uncharacterized protein. (352 aa)
ENSCPOP00000031848PUM-HD domain-containing protein. (204 aa)
LOC106027361Uncharacterized protein. (1433 aa)
DEKDEK proto-oncogene. (374 aa)
LOC100718706Nudix hydrolase domain-containing protein. (194 aa)
Nol12Uncharacterized protein. (214 aa)
SMUG1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (272 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (567 aa)
ENSCPOP00000032877PCI domain-containing protein. (324 aa)
YPEL4Protein yippee-like; Belongs to the yippee family. (127 aa)
ETV6ETS variant 6. (449 aa)
RASL11ARAS like family 11 member A. (242 aa)
RPS10-NUDT3S10_plectin domain-containing protein. (165 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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