STRINGSTRING
MAIP1 MAIP1 DNAJC15 DNAJC15 ACSS3 ACSS3 SSBP1 SSBP1 MRPS31 MRPS31 POLDIP2 POLDIP2 PDHX PDHX SUCLG1 SUCLG1 PRIMPOL PRIMPOL LOC100723477 LOC100723477 HSPA9 HSPA9 Mrpl47 Mrpl47 MRPS30 MRPS30 TIMM44 TIMM44 LOC100713838 LOC100713838 PDE12 PDE12 MRPL45 MRPL45 IDH3A IDH3A PITRM1 PITRM1 MRPS7 MRPS7 MLYCD MLYCD TWNK TWNK GLRX5 GLRX5 MRPL11 MRPL11 Bckdha Bckdha Lrpprc Lrpprc MRPL10 MRPL10 MRPL46 MRPL46 MRPL57 MRPL57 MIEF1 MIEF1 TRAP1 TRAP1 MRPS33 MRPS33 FDX1 FDX1 DLAT DLAT MRPL12 MRPL12 MRPS10 MRPS10 MPV17L2 MPV17L2 MRPL21 MRPL21 GRPEL2 GRPEL2 MRPL33 MRPL33 NSUN3 NSUN3 ENSCPOP00000033036 ENSCPOP00000033036 MRPL20 MRPL20 PRDX1 PRDX1 LRRC59 LRRC59 MRPS36 MRPS36 PCCB PCCB HAGH HAGH TM2D2 TM2D2 MRPS22 MRPS22 MRPS24 MRPS24 AK4 AK4 MTG1 MTG1 MRPL50 MRPL50 PAM16 PAM16 MRPS12 MRPS12 ENSCPOP00000025122 ENSCPOP00000025122 PC PC MRPL15 MRPL15 SIRT5 SIRT5 MRPL41 MRPL41 MRPS26 MRPS26 MRPL14 MRPL14 BCKDHB BCKDHB BCKDK BCKDK MRPL53 MRPL53 DNA2 DNA2 MRPS14 MRPS14 DHX30 DHX30 MRPL49 MRPL49 IDH3G IDH3G MRPL3 MRPL3 MRPL58 MRPL58 Mrpl42 Mrpl42 CREB1 CREB1 SOD2 SOD2 PDK1 PDK1 ENSCPOP00000021625 ENSCPOP00000021625 LYRM7 LYRM7 HAGHL HAGHL MRPL1 MRPL1 DAP3 DAP3 ENSCPOP00000021986 ENSCPOP00000021986 CLPX CLPX GRPEL1 GRPEL1 PPIF PPIF DDX28 DDX28 ALKBH7 ALKBH7 MRPS9 MRPS9 Parl Parl MRPL55 MRPL55 MRPS11 MRPS11 NUDT1 NUDT1 Nfs1 Nfs1 MRPL24 MRPL24 MMUT MMUT CS CS ACAT1 ACAT1 IDH3B IDH3B FDPS FDPS MRPS18B MRPS18B ACADS ACADS TYMS TYMS MRPL19 MRPL19 Wee2 Wee2 MARS2 MARS2 ACADVL ACADVL TST TST PPP1R26 PPP1R26 ATAD3A ATAD3A MRPL9 MRPL9 MRPL40 MRPL40 MTERF4 MTERF4 DTYMK DTYMK MRPS25 MRPS25 HSPD1 HSPD1 MRPL27 MRPL27 MRPS16 MRPS16 MRPL39 MRPL39 PDK2 PDK2 MRPL38 MRPL38 ACSS1 ACSS1 FASTKD5 FASTKD5 MRPS18A MRPS18A MRPS21 MRPS21 IVD IVD MTG2 MTG2 Mrpl23 Mrpl23 LOC100715002 LOC100715002 MRPL34 MRPL34 MRPL54 MRPL54 ACSM1 ACSM1 UQCC2 UQCC2 MIPEP MIPEP MRPL18 MRPL18 TFAM TFAM MRPS2 MRPS2 ENSCPOP00000029518 ENSCPOP00000029518 SARDH SARDH GLRX2 GLRX2 MRPL43 MRPL43 MRPL35 MRPL35 MRPL32 MRPL32 MRPL36 MRPL36 MRPL17 MRPL17 MRPS6 MRPS6 TFB1M TFB1M CCDC32 CCDC32 LONP1 LONP1 SIRT3 SIRT3 MRPL44 MRPL44 OGDHL OGDHL H0W9P9_CAVPO H0W9P9_CAVPO DNAJC19 DNAJC19 H0WAF5_CAVPO H0WAF5_CAVPO Mrpl2 Mrpl2 ACOT13 ACOT13 LOC100725076 LOC100725076 GSTK1 GSTK1 C3orf18 C3orf18 Mrps17 Mrps17 TOP1MT TOP1MT MRPS27 MRPS27 SUCLG2 SUCLG2 NAGK NAGK MRPL48 MRPL48 Tfb2m Tfb2m MTHFD1 MTHFD1 CAPN10 CAPN10 PTCD3 PTCD3 SIRT4 SIRT4 AK3 AK3 TEFM TEFM MRPL37 MRPL37 GRSF1 GRSF1 PCCA PCCA ACADM ACADM Atxn3 Atxn3 MRPS15 MRPS15 MCCC1 MCCC1 Mrpl30 Mrpl30 MRPS35 MRPS35 REXO2 REXO2 TUFM TUFM OAT OAT DGLUCY DGLUCY NDUFA9 NDUFA9 MDH2 MDH2 SUPV3L1 SUPV3L1 ACADL ACADL ERAL1 ERAL1 MRPL52 MRPL52 SLC25A5 SLC25A5 MRPS18C MRPS18C ELAC2 ELAC2 ACSM3 ACSM3 MRPS23 MRPS23 DNAJA3 DNAJA3 MRPL51 MRPL51 PMPCB PMPCB POLG POLG PMPCA PMPCA MRPL28 MRPL28 POLG2 POLG2 MTERF2 MTERF2 C3orf20 C3orf20 NSUN4 NSUN4 DBT DBT MRPL22 MRPL22 PDHB PDHB MRPL4 MRPL4 HMGCS2 HMGCS2 COASY COASY HADHA HADHA METTL4 METTL4 MRPL13 MRPL13 FASTKD2 FASTKD2 HADHB HADHB MRPS34 MRPS34 Glud1 Glud1 MRPL16 MRPL16 H0V3Y8_CAVPO H0V3Y8_CAVPO ACAA2 ACAA2 MRPS5 MRPS5 MRM1 MRM1 CPS1 CPS1 ETFBKMT ETFBKMT MTERF1 MTERF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAIP1Matrix AAA peptidase interacting protein 1. (273 aa)
DNAJC15DnaJ heat shock protein family (Hsp40) member C15. (149 aa)
ACSS3Acyl-CoA synthetase short chain family member 3. (682 aa)
SSBP1Single stranded DNA binding protein 1. (137 aa)
MRPS31Mitochondrial ribosomal protein S31. (383 aa)
POLDIP2DNA polymerase delta interacting protein 2. (368 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (442 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
PRIMPOLPrimase and DNA directed polymerase. (547 aa)
LOC100723477Uncharacterized protein. (456 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (678 aa)
Mrpl47Uncharacterized protein. (251 aa)
MRPS30Mitochondrial ribosomal protein S30. (421 aa)
TIMM44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (452 aa)
LOC100713838Uncharacterized protein. (705 aa)
PDE12Phosphodiesterase 12. (608 aa)
MRPL45Mitochondrial ribosomal protein L45. (307 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (379 aa)
PITRM1Pitrilysin metallopeptidase 1. (1032 aa)
MRPS7Mitochondrial ribosomal protein S7. (242 aa)
MLYCDMalonyl-CoA decarboxylase. (488 aa)
TWNKTwinkle mtDNA helicase. (670 aa)
GLRX5Glutaredoxin 5. (156 aa)
MRPL11Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. (192 aa)
Bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
LrpprcPPR_long domain-containing protein. (1203 aa)
MRPL10Mitochondrial ribosomal protein L10. (262 aa)
MRPL46Mitochondrial ribosomal protein L46. (280 aa)
MRPL57Mitochondrial ribosomal protein L57. (102 aa)
MIEF1Mitochondrial elongation factor 1. (463 aa)
TRAP1TNF receptor associated protein 1. (706 aa)
MRPS33Mitochondrial ribosomal protein S33. (106 aa)
FDX1Ferredoxin 1. (124 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (650 aa)
MRPL12Mitochondrial ribosomal protein L12. (199 aa)
MRPS10Mitochondrial ribosomal protein S10. (201 aa)
MPV17L2MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (210 aa)
MRPL21Mitochondrial ribosomal protein L21. (209 aa)
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (225 aa)
MRPL33Mitochondrial ribosomal protein L33. (65 aa)
NSUN3NOP2/Sun RNA methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (334 aa)
ENSCPOP00000033036Uncharacterized protein; Belongs to the GroES chaperonin family. (85 aa)
MRPL20Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family. (149 aa)
PRDX1Peroxiredoxin 1. (199 aa)
LRRC59Leucine rich repeat containing 59. (307 aa)
MRPS36Mitochondrial ribosomal protein S36. (100 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (539 aa)
HAGHHydroxyacylglutathione hydrolase. (260 aa)
TM2D2TM2 domain containing 2. (214 aa)
MRPS22Mitochondrial ribosomal protein S22. (361 aa)
MRPS24Mitochondrial ribosomal protein S24. (166 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
MTG1Mitochondrial GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (333 aa)
MRPL50Mitochondrial ribosomal protein L50. (158 aa)
PAM16Presequence translocase associated motor 16. (121 aa)
MRPS12Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (139 aa)
ENSCPOP00000025122Uncharacterized protein. (122 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1219 aa)
MRPL15Mitochondrial ribosomal protein L15. (296 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (309 aa)
MRPL41Mitochondrial ribosomal protein L41. (135 aa)
MRPS26Mitochondrial ribosomal protein S26. (248 aa)
MRPL14Mitochondrial ribosomal protein L14. (145 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (392 aa)
BCKDKProtein-serine/threonine kinase. (412 aa)
MRPL53Mitochondrial ribosomal protein L53. (112 aa)
DNA2DNA replication helicase/nuclease 2. (1021 aa)
MRPS14Mitochondrial ribosomal protein S14. (128 aa)
DHX30DExH-box helicase 30. (1218 aa)
MRPL49Mitochondrial ribosomal protein L49. (166 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (393 aa)
MRPL3Mitochondrial ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (348 aa)
MRPL58Mitochondrial ribosomal protein L58. (206 aa)
Mrpl42Uncharacterized protein. (143 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
ENSCPOP00000021625Josephin domain-containing protein. (177 aa)
LYRM7LYR motif containing 7; Belongs to the complex I LYR family. (104 aa)
HAGHLHydroxyacylglutathione hydrolase like. (228 aa)
MRPL1Mitochondrial ribosomal protein L1. (324 aa)
DAP3Death associated protein 3. (397 aa)
ENSCPOP00000021986Uncharacterized protein. (224 aa)
CLPXCaseinolytic mitochondrial matrix peptidase chaperone subunit. (633 aa)
GRPEL1GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
DDX28DEAD-box helicase 28. (537 aa)
ALKBH7AlkB homolog 7. (218 aa)
MRPS9Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (396 aa)
ParlRhomboid domain-containing protein. (379 aa)
MRPL55Mitochondrial ribosomal protein L55. (128 aa)
MRPS11Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (192 aa)
NUDT1Nudix hydrolase 1; Belongs to the Nudix hydrolase family. (156 aa)
Nfs1Aminotran_5 domain-containing protein. (436 aa)
MRPL24Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family. (216 aa)
MMUTMethylmalonyl-CoA mutase. (749 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (352 aa)
MRPS18BMitochondrial ribosomal protein S18B. (259 aa)
ACADSAcyl-CoA dehydrogenase short chain. (413 aa)
TYMSThymidylate synthetase. (314 aa)
MRPL19Mitochondrial ribosomal protein L19. (292 aa)
Wee2Wee1-like protein kinase. (557 aa)
MARS2Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (592 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (633 aa)
TSTSulfurtransferase. (297 aa)
PPP1R26Protein phosphatase 1 regulatory subunit 26. (1240 aa)
ATAD3AATPase family AAA domain containing 3A. (584 aa)
MRPL9Mitochondrial ribosomal protein L9. (270 aa)
MRPL40Mitochondrial ribosomal protein L40. (205 aa)
MTERF4Mitochondrial transcription termination factor 4. (341 aa)
DTYMKDeoxythymidylate kinase. (212 aa)
MRPS25Mitochondrial ribosomal protein S25. (173 aa)
HSPD1Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (574 aa)
MRPL27Mitochondrial ribosomal protein L27. (148 aa)
MRPS16Mitochondrial ribosomal protein S16. (135 aa)
MRPL39Mitochondrial ribosomal protein L39. (335 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
MRPL38Mitochondrial ribosomal protein L38. (380 aa)
ACSS1Acetyl-coenzyme A synthetase. (647 aa)
FASTKD5FAST kinase domains 5. (795 aa)
MRPS18AMitochondrial ribosomal protein S18A. (196 aa)
MRPS21Mitochondrial ribosomal protein S21. (87 aa)
IVDIsovaleryl-CoA dehydrogenase. (426 aa)
MTG2Mitochondrial ribosome associated GTPase 2. (459 aa)
Mrpl23Uncharacterized protein. (149 aa)
LOC100715002Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
MRPL34Mitochondrial ribosomal protein L34. (86 aa)
MRPL54Mitochondrial ribosomal protein L54. (138 aa)
ACSM1Acyl-CoA synthetase medium chain family member 1. (524 aa)
UQCC2Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa)
MIPEPMitochondrial intermediate peptidase. (713 aa)
MRPL18Mitochondrial ribosomal protein L18. (204 aa)
TFAMTranscription factor A, mitochondrial. (235 aa)
MRPS2Mitochondrial ribosomal protein S2. (285 aa)
ENSCPOP00000029518Uncharacterized protein. (106 aa)
SARDHSarcosine dehydrogenase. (919 aa)
GLRX2Glutaredoxin 2. (160 aa)
MRPL43Mitochondrial ribosomal protein L43. (159 aa)
MRPL35Mitochondrial ribosomal protein L35. (201 aa)
MRPL32Mitochondrial ribosomal protein L32. (184 aa)
MRPL36Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family. (102 aa)
MRPL17Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. (176 aa)
MRPS6Mitochondrial ribosomal protein S6. (109 aa)
TFB1MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (346 aa)
CCDC32Coiled-coil domain containing 32. (178 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (1003 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (257 aa)
MRPL44Mitochondrial ribosomal protein L44. (332 aa)
OGDHLOxoglutarate dehydrogenase like. (1022 aa)
H0W9P9_CAVPOWee1-like protein kinase. (551 aa)
DNAJC19DnaJ heat shock protein family (Hsp40) member C19. (130 aa)
H0WAF5_CAVPOIso_dh domain-containing protein. (332 aa)
Mrpl2Mitochondrial ribosomal protein L2. (305 aa)
ACOT13Acyl-CoA thioesterase 13. (140 aa)
LOC100725076Iso_dh domain-containing protein. (377 aa)
GSTK1Glutathione S-transferase kappa. (226 aa)
C3orf18Chromosome 3 open reading frame 18. (154 aa)
Mrps17Uncharacterized protein. (30 aa)
TOP1MTDNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (629 aa)
MRPS27Mitochondrial ribosomal protein S27. (415 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (404 aa)
NAGKN-acetylglucosamine kinase. (345 aa)
MRPL48Mitochondrial ribosomal protein L48. (212 aa)
Tfb2mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (392 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (928 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (667 aa)
PTCD3Pentatricopeptide repeat domain 3. (690 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (228 aa)
TEFMTranscription elongation factor, mitochondrial. (356 aa)
MRPL37Mitochondrial ribosomal protein L37. (419 aa)
GRSF1G-rich RNA sequence binding factor 1. (471 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (728 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (363 aa)
Atxn3Josephin domain-containing protein. (351 aa)
MRPS15Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family. (254 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (725 aa)
Mrpl30Ribosomal_L30 domain-containing protein. (155 aa)
MRPS35Mitochondrial ribosomal protein S35. (288 aa)
REXO2RNA exonuclease 2. (237 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (452 aa)
OATOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
DGLUCYD-glutamate cyclase. (554 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
MDH2Malate dehydrogenase. (338 aa)
SUPV3L1Suv3 like RNA helicase. (786 aa)
ACADLAcyl-CoA dehydrogenase long chain. (432 aa)
ERAL1Era like 12S mitochondrial rRNA chaperone 1. (437 aa)
MRPL52Mitochondrial ribosomal protein L52. (123 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
MRPS18CMitochondrial ribosomal protein S18C; Belongs to the bacterial ribosomal protein bS18 family. (144 aa)
ELAC2ElaC ribonuclease Z 2. (833 aa)
ACSM3Acyl-CoA synthetase medium chain family member 3. (585 aa)
MRPS23Mitochondrial ribosomal protein S23. (140 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (479 aa)
MRPL51Mitochondrial ribosomal protein L51. (128 aa)
PMPCBPeptidase, mitochondrial processing beta subunit; Belongs to the peptidase M16 family. (490 aa)
POLGDNA polymerase gamma, catalytic subunit. (1206 aa)
PMPCAPeptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family. (527 aa)
MRPL28Mitochondrial ribosomal protein L28. (256 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (482 aa)
MTERF2Mitochondrial transcription termination factor 2. (389 aa)
C3orf20Chromosome 3 open reading frame 20. (898 aa)
NSUN4NOP2/Sun RNA methyltransferase 4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (381 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
MRPL22Mitochondrial ribosomal protein L22; Belongs to the universal ribosomal protein uL22 family. (210 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
MRPL4Mitochondrial ribosomal protein L4. (296 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
COASYCoenzyme A synthase. (563 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
METTL4Methyltransferase like 4; Belongs to the MT-A70-like family. (470 aa)
MRPL13Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. (178 aa)
FASTKD2FAST kinase domains 2. (673 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (487 aa)
MRPS34Mitochondrial ribosomal protein S34. (218 aa)
Glud1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (540 aa)
MRPL16Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. (251 aa)
H0V3Y8_CAVPOPRORP domain-containing protein. (566 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
MRPS5Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (431 aa)
MRM1Mitochondrial rRNA methyltransferase 1. (350 aa)
CPS1Carbamoyl-phosphate synthase 1. (1499 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (254 aa)
MTERF1Mitochondrial transcription termination factor 1. (409 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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