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SLC9A3R2 SLC9A3R2 LOC101787631 LOC101787631 UPK3A UPK3A SLCO2B1 SLCO2B1 LOC100727821 LOC100727821 SLC2A5 SLC2A5 SLC26A3 SLC26A3 SLC12A2 SLC12A2 PTPRO PTPRO P2RX2 P2RX2 Scnn1b Scnn1b CASR CASR NOTCH1 NOTCH1 MYO1A MYO1A FN1 FN1 CFTR CFTR AKR1A1 AKR1A1 CDCP2 CDCP2 Scnn1d Scnn1d SLC5A2 SLC5A2 Aqp1 Aqp1 ABCC5 ABCC5 SLC47A1 SLC47A1 TRPM6 TRPM6 TJP1 TJP1 SLC6A19 SLC6A19 ATP6V1B1 ATP6V1B1 H0VGL3_CAVPO H0VGL3_CAVPO CD81 CD81 SLC5A8 SLC5A8 Plpp1 Plpp1 ATP6V0D2 ATP6V0D2 SLC26A9 SLC26A9 CTSB CTSB RHCG RHCG Dab2 Dab2 SLC28A1 SLC28A1 SLC12A3 SLC12A3 Slc14a2 Slc14a2 SLC22A8 SLC22A8 SLC17A1 SLC17A1 HAX1 HAX1 SLC5A4 SLC5A4 SLC5A1 SLC5A1 CUBN CUBN SLC15A2 SLC15A2 ATP8B1 ATP8B1 SLC9A3 SLC9A3 ABCB11 ABCB11 Ocln Ocln PDZK1 PDZK1 SLC38A1 SLC38A1 HYAL2 HYAL2 AQP8 AQP8 SLC29A1 SLC29A1 SLC12A1 SLC12A1 CBLIF CBLIF SLC22A4 SLC22A4 ABCC6 ABCC6 ABCC1 ABCC1 SLC4A7 SLC4A7 SLC34A1 SLC34A1 UPK1B UPK1B ATP1B3 ATP1B3 SYTL4 SYTL4 UPK1A UPK1A SLC46A1 SLC46A1 F2RL2 F2RL2 ACY3 ACY3 SLC26A4 SLC26A4 UPK2 UPK2 SLC22A2 SLC22A2 Lmo7 Lmo7 SLC15A1 SLC15A1 SLC10A2 SLC10A2 LOC100727546 LOC100727546 PTK2 PTK2 Gp2 Gp2 ENPEP ENPEP SLC16A2 SLC16A2 ABCG8 ABCG8 TRPV5 TRPV5 RAB27B RAB27B EZR EZR RAB27A RAB27A LOC100725073 LOC100725073 LOC100715013 LOC100715013 ENSCPOP00000031266 ENSCPOP00000031266 MSN MSN CD9 CD9 DSTYK DSTYK SLC26A6 SLC26A6 STX3 STX3 ATP4A ATP4A ANO1 ANO1 ATP1B1 ATP1B1 SLC9A1 SLC9A1 KCNMA1 KCNMA1 P2RY2 P2RY2 EXOC1 EXOC1 ATP6V0A4 ATP6V0A4 VAMP3 VAMP3 ENSCPOP00000025593 ENSCPOP00000025593 ENSCPOP00000024297 ENSCPOP00000024297 MAL MAL ENSCPOP00000023326 ENSCPOP00000023326 CLDN1 CLDN1 ENSCPOP00000022694 ENSCPOP00000022694 Muc1 Muc1 Scnn1g Scnn1g RDX RDX LOC100717354 LOC100717354 LOC100721472 LOC100721472 MYO7A MYO7A LOC100721750 LOC100721750 PATJ PATJ H0WB32_CAVPO H0WB32_CAVPO LOC100716808 LOC100716808 CYBRD1 CYBRD1 SLC22A12 SLC22A12 KCNA5 KCNA5 LOC100717081 LOC100717081 PTEN PTEN ATP7A ATP7A H0W482_CAVPO H0W482_CAVPO H0W3X9_CAVPO H0W3X9_CAVPO ATP2B2 ATP2B2 Aspm Aspm SCNN1A SCNN1A STXBP2 STXBP2 SLC34A2 SLC34A2 AQP5 AQP5
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
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SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (337 aa)
LOC101787631G_PROTEIN_RECEP_F3_4 domain-containing protein. (871 aa)
UPK3AUroplakin 3A. (289 aa)
SLCO2B1Solute carrier organic anion transporter family member. (709 aa)
LOC100727821VWFA domain-containing protein. (923 aa)
SLC2A5Solute carrier family 2 member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (501 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (754 aa)
SLC12A2Solute carrier family 12 member 2. (1136 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
P2RX2P2X purinoceptor 2; Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity); Belongs to the P2X receptor family. (411 aa)
Scnn1bUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
CASRCalcium sensing receptor. (1071 aa)
NOTCH1Notch receptor 1. (2472 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
FN1Fibronectin 1. (2478 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (325 aa)
CDCP2CUB domain containing protein 2. (399 aa)
Scnn1dUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (618 aa)
SLC5A2Solute carrier family 5 member 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa)
Aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
SLC47A1Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (521 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (1902 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1754 aa)
SLC6A19Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (633 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
H0VGL3_CAVPOASD2 domain-containing protein. (446 aa)
CD81Tetraspanin. (236 aa)
SLC5A8Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (611 aa)
Plpp1Phospholipid phosphatase 1; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1- phosphate/C1P. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity). Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these b [...] (284 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (789 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (340 aa)
RHCGRh family C glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (363 aa)
Dab2PID domain-containing protein. (766 aa)
SLC28A1Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (644 aa)
SLC12A3Solute carrier family 12 member 3. (1004 aa)
Slc14a2Uncharacterized protein. (900 aa)
SLC22A8Solute carrier family 22 member 8. (538 aa)
SLC17A1Solute carrier family 17 member 1. (456 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (278 aa)
SLC5A4Solute carrier family 5 member 4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (660 aa)
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (661 aa)
CUBNCubilin. (3557 aa)
SLC15A2Solute carrier family 15 member 2. (690 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1146 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (832 aa)
ABCB11Uncharacterized protein. (1320 aa)
OclnOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
PDZK1PDZ domain containing 1. (513 aa)
SLC38A1Solute carrier family 38 member 1. (485 aa)
HYAL2Hyaluronidase. (471 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (252 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (461 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
CBLIFCobalamin binding intrinsic factor. (411 aa)
SLC22A4Solute carrier family 22 member 4. (541 aa)
ABCC6ATP binding cassette subfamily C member 6. (1436 aa)
ABCC1ATP binding cassette subfamily C member 1. (1531 aa)
SLC4A7Anion exchange protein. (1049 aa)
SLC34A1Solute carrier family 34 member 1. (638 aa)
UPK1BUroplakin 1B; Belongs to the tetraspanin (TM4SF) family. (260 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (By similarity); Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
SYTL4Synaptotagmin like 4. (671 aa)
UPK1ATetraspanin. (257 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
F2RL2Coagulation factor II thrombin receptor like 2. (329 aa)
ACY3Aminoacylase 3. (318 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (739 aa)
UPK2Uroplakin 2. (184 aa)
SLC22A2Solute carrier family 22 member 2. (514 aa)
Lmo7Uncharacterized protein. (471 aa)
SLC15A1Solute carrier family 15 member 1. (708 aa)
SLC10A2Solute carrier family 10 member 2. (349 aa)
LOC100727546VWFA domain-containing protein. (923 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
Gp2ZP domain-containing protein. (526 aa)
ENPEPAminopeptidase. (898 aa)
SLC16A2Solute carrier family 16 member 2. (535 aa)
ABCG8ATP binding cassette subfamily G member 8. (658 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
EZREzrin. (586 aa)
RAB27ARAB27A, member RAS oncogene family. (220 aa)
LOC100725073PID domain-containing protein. (745 aa)
LOC100715013Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (578 aa)
ENSCPOP00000031266Uncharacterized protein. (366 aa)
MSNMoesin. (577 aa)
CD9Tetraspanin. (227 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (927 aa)
SLC26A6STAS domain-containing protein. (725 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (288 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
ANO1Anoctamin. (1011 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (306 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1133 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (376 aa)
EXOC1Exocyst complex component 1. (911 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa)
VAMP3Vesicle associated membrane protein 3. (100 aa)
ENSCPOP00000025593Uncharacterized protein. (180 aa)
ENSCPOP00000024297Uncharacterized protein. (406 aa)
MALMal, T cell differentiation protein. (153 aa)
ENSCPOP00000023326Uncharacterized protein. (373 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
ENSCPOP00000022694Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (305 aa)
Muc1SEA domain-containing protein. (640 aa)
Scnn1gUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (653 aa)
RDXRadixin. (604 aa)
LOC100717354G_PROTEIN_RECEP_F3_4 domain-containing protein. (886 aa)
LOC100721472G_PROTEIN_RECEP_F3_4 domain-containing protein. (888 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2203 aa)
LOC100721750G_PROTEIN_RECEP_F3_4 domain-containing protein. (713 aa)
PATJPATJ crumbs cell polarity complex component. (1884 aa)
H0WB32_CAVPOSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (177 aa)
LOC100716808G_PROTEIN_RECEP_F3_4 domain-containing protein. (856 aa)
CYBRD1Cytochrome b reductase 1. (218 aa)
SLC22A12Solute carrier family 22 member 12. (552 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa)
LOC100717081G_PROTEIN_RECEP_F3_4 domain-containing protein. (710 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
ATP7AATPase copper transporting alpha. (1433 aa)
H0W482_CAVPOUncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (645 aa)
H0W3X9_CAVPOUncharacterized protein. (2048 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa)
AspmUncharacterized protein. (1053 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. Belongs to the amilori [...] (680 aa)
STXBP2Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
SLC34A2Solute carrier family 34 member 2. (749 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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