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| | NFYC | Nuclear transcription factor Y subunit gamma. (335 aa) |
| | LOC100734314 | annotation not available (130 aa) |
| | Morf4l1 | Mortality factor 4 like 1. (377 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1584 aa) |
| | NFE2 | Nuclear factor, erythroid 2. (373 aa) |
| | GTF2B | General transcription factor IIB. (308 aa) |
| | YEATS4 | YEATS domain containing 4. (227 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) |
| | LOC100731150 | annotation not available (103 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (898 aa) |
| | GTF2E1 | General transcription factor IIE subunit 1. (440 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (768 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | Chd4 | Uncharacterized protein. (1900 aa) |
| | EPC2 | Enhancer of polycomb homolog. (803 aa) |
| | DMRT2 | Doublesex and mab-3 related transcription factor 2. (559 aa) |
| | FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (987 aa) |
| | KDM5A | Lysine demethylase 5A. (1527 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4043 aa) |
| | TBX5 | T-box transcription factor 5. (518 aa) |
| | LOC100735848 | TINF2_N domain-containing protein. (416 aa) |
| | ORC3 | Origin recognition complex subunit 3. (710 aa) |
| | TNP1 | Transition protein 1. (55 aa) |
| | Parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa) |
| | JUND | JunD proto-oncogene, AP-1 transcription factor subunit. (320 aa) |
| | TREX1 | Three prime repair exonuclease 1. (314 aa) |
| | SAPCD1 | Suppressor APC domain containing 1. (163 aa) |
| | Prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa) |
| | SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (737 aa) |
| | SP8 | Sp8 transcription factor. (463 aa) |
| | NKX2-5 | NK2 homeobox 5. (303 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (445 aa) |
| | ESR2 | Estrogen receptor 2. (568 aa) |
| | ING3 | Inhibitor of growth protein. (418 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (469 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (731 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | MYOG | Myogenin. (249 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (549 aa) |
| | LOC111756490 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | H2AZ1 | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | TEAD4 | Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (450 aa) |
| | MRGBP | MRG domain binding protein. (204 aa) |
| | H3F3B | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | SOX12 | Transcription factor SOX. (310 aa) |
| | POLD1 | DNA polymerase. (1134 aa) |
| | PAX2 | Paired box 2. (393 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | Pold4 | Uncharacterized protein. (107 aa) |
| | LOC100713713 | annotation not available (130 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (350 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | SP9 | Sp9 transcription factor. (374 aa) |
| | Hhex | Homeobox domain-containing protein. (98 aa) |
| | IKZF1 | IKAROS family zinc finger 1. (511 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (396 aa) |
| | ENSCPOP00000023972 | MRG domain-containing protein. (235 aa) |
| | H3-3A | H3.3 histone A. (136 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3860 aa) |
| | LOC100733876 | annotation not available (103 aa) |
| | ENSCPOP00000024347 | annotation not available (103 aa) |
| | ENSCPOP00000024428 | PARP-type domain-containing protein. (104 aa) |
| | ENSCPOP00000024582 | MRG domain-containing protein. (291 aa) |
| | TBX4 | T-box transcription factor 4. (452 aa) |
| | ENSCPOP00000024875 | MRG domain-containing protein. (231 aa) |
| | GINS3 | GINS complex subunit 3. (216 aa) |
| | LOC100728325 | annotation not available (103 aa) |
| | Morf4l2 | MRG domain-containing protein. (288 aa) |
| | CDC45 | Cell division cycle 45. (566 aa) |
| | STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (375 aa) |
| | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1. (1084 aa) |
| | SPHK2 | Sphingosine kinase 2. (655 aa) |
| | ENSCPOP00000027071 | annotation not available (130 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (171 aa) |
| | DBF4 | DBF4 zinc finger. (675 aa) |
| | GATA1 | GATA binding protein 1. (401 aa) |
| | Pold3 | Uncharacterized protein. (466 aa) |
| | KDM1B | Lysine demethylase 1B. (831 aa) |
| | DONSON | Downstream neighbor of SON. (553 aa) |
| | TMEM232 | Transmembrane protein 232. (607 aa) |
| | PRIM2 | DNA primase subunit 2. (432 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | IRF4 | Interferon regulatory factor 4. (452 aa) |
| | GTF2A1 | General transcription factor IIA subunit 1. (377 aa) |
| | NFYB | Nuclear transcription factor Y subunit beta. (206 aa) |
| | MPHOSPH8 | M-phase phosphoprotein 8. (858 aa) |
| | EPC1 | Enhancer of polycomb homolog 1. (763 aa) |
| | POLA1 | DNA polymerase. (1467 aa) |
| | THSD7B | Thrombospondin type 1 domain containing 7B. (1606 aa) |
| | Pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | DDAH2 | Dimethylarginine dimethylaminohydrolase 2. (285 aa) |
| | CDC5L | Cell division cycle 5 like. (802 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (810 aa) |
| | H2AZ2 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (280 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | H2AC20 | Histone H2A; Belongs to the histone H2A family. (110 aa) |
| | ENSCPOP00000029297 | annotation not available (103 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (579 aa) |
| | DARS2 | Aspartyl-tRNA synthetase 2, mitochondrial. (654 aa) |
| | GLYR1 | Glyoxylate reductase 1 homolog. (553 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (938 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa) |
| | H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | H0VN16_CAVPO | Uncharacterized protein. (71 aa) |
| | C19orf53 | Chromosome 19 open reading frame 53. (99 aa) |
| | ENSCPOP00000027965 | Bromo domain-containing protein. (321 aa) |
| | Ten1 | Uncharacterized protein. (122 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (591 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) |
| | LOC100712757 | TINF2_N domain-containing protein. (397 aa) |
| | CENPA | Centromere protein A. (131 aa) |
| | EP400 | E1A binding protein p400. (3128 aa) |
| | MBTD1 | Mbt domain containing 1. (627 aa) |
