7 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CYP1A2	Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (515 aa)
	Ahr	Uncharacterized protein. (832 aa)
	Ahrr	Uncharacterized protein. (654 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2. (715 aa)
	Arnt	Uncharacterized protein. (775 aa)
	AIP	Aryl hydrocarbon receptor interacting protein. (330 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (540 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIP	Ahr	ENSCPOP00000015770	ENSCPOP00000004936	Aryl hydrocarbon receptor interacting protein.	Uncharacterized protein.	0.996
AIP	Ahrr	ENSCPOP00000015770	ENSCPOP00000005402	Aryl hydrocarbon receptor interacting protein.	Uncharacterized protein.	0.908
ARNT2	Ahr	ENSCPOP00000011702	ENSCPOP00000004936	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.985
ARNT2	Ahrr	ENSCPOP00000011702	ENSCPOP00000005402	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.889
ARNT2	Arnt	ENSCPOP00000011702	ENSCPOP00000013135	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.911
ARNT2	CYP1B1	ENSCPOP00000011702	ENSCPOP00000028327	Aryl hydrocarbon receptor nuclear translocator 2.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.466
Ahr	AIP	ENSCPOP00000004936	ENSCPOP00000015770	Uncharacterized protein.	Aryl hydrocarbon receptor interacting protein.	0.996
Ahr	ARNT2	ENSCPOP00000004936	ENSCPOP00000011702	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.985
Ahr	Arnt	ENSCPOP00000004936	ENSCPOP00000013135	Uncharacterized protein.	Uncharacterized protein.	0.992
Ahr	CYP1A2	ENSCPOP00000004936	ENSCPOP00000017610	Uncharacterized protein.	Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...]	0.547
Ahr	CYP1B1	ENSCPOP00000004936	ENSCPOP00000028327	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.481
Ahrr	AIP	ENSCPOP00000005402	ENSCPOP00000015770	Uncharacterized protein.	Aryl hydrocarbon receptor interacting protein.	0.908
Ahrr	ARNT2	ENSCPOP00000005402	ENSCPOP00000011702	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.889
Ahrr	Arnt	ENSCPOP00000005402	ENSCPOP00000013135	Uncharacterized protein.	Uncharacterized protein.	0.889
Ahrr	CYP1B1	ENSCPOP00000005402	ENSCPOP00000028327	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.454
Arnt	ARNT2	ENSCPOP00000013135	ENSCPOP00000011702	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.911
Arnt	Ahr	ENSCPOP00000013135	ENSCPOP00000004936	Uncharacterized protein.	Uncharacterized protein.	0.992
Arnt	Ahrr	ENSCPOP00000013135	ENSCPOP00000005402	Uncharacterized protein.	Uncharacterized protein.	0.889
Arnt	CYP1A2	ENSCPOP00000013135	ENSCPOP00000017610	Uncharacterized protein.	Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...]	0.509
Arnt	CYP1B1	ENSCPOP00000013135	ENSCPOP00000028327	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.533