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CADM1 CADM1 CDH10 CDH10 GRIA2 GRIA2 GRIA4 GRIA4 GABRA3 GABRA3 KCND3 KCND3 DCC DCC SLC1A6 SLC1A6 CACNG2 CACNG2 DRD3 DRD3 GABRD GABRD ADCY1 ADCY1 CDH9 CDH9 CANX CANX GRIA3 GRIA3 EPHA7 EPHA7 GRIA1 GRIA1 GABRA5 GABRA5 NCAM1 NCAM1 SLITRK3 SLITRK3 LRFN5 LRFN5 CHRND CHRND GABRB3 GABRB3 LRRTM3 LRRTM3 GRM2 GRM2 GRIN2B GRIN2B GABBR2 GABBR2 PLPPR4 PLPPR4 LRFN4 LRFN4 GRIN3A GRIN3A GABRA1 GABRA1 SLC6A11 SLC6A11 HTR5A HTR5A CLSTN3 CLSTN3 ADGRB1 ADGRB1 CHRNA9 CHRNA9 GABRA4 GABRA4 NECTIN3 NECTIN3 NETO1 NETO1 LRRC7 LRRC7 H0VF00_CAVPO H0VF00_CAVPO CHRNA6 CHRNA6 SLC8A2 SLC8A2 CSPG5 CSPG5 PTPRF PTPRF GRID1 GRID1 GSG1L GSG1L SLC1A7 SLC1A7 EPHB2 EPHB2 EPHA4 EPHA4 ERBB4 ERBB4 GRID2 GRID2 Slc6a8 Slc6a8 GRIN3B GRIN3B LRRTM4 LRRTM4 GLRA3 GLRA3 CACNA1H CACNA1H CHRNA3 CHRNA3 KCNC4 KCNC4 P2RX6 P2RX6 PTPRS PTPRS LOC100730761 LOC100730761 IL1RAPL1 IL1RAPL1 GRIN2A GRIN2A SLC30A1 SLC30A1 GLRA1 GLRA1 GRM3 GRM3 SORCS3 SORCS3 SLITRK1 SLITRK1 PTPRT PTPRT CHRM2 CHRM2 CHRNB1 CHRNB1 CACNA1E CACNA1E PCDH8 PCDH8 SLC6A6 SLC6A6 LRRTM2 LRRTM2 SCN8A SCN8A GLRA4 GLRA4 KCNA3 KCNA3 LRRC4C LRRC4C SLC16A3 SLC16A3 CACNG4 CACNG4 SLC6A1 SLC6A1 LRRTM1 LRRTM1 GABRA2 GABRA2 ATP2B2 ATP2B2 LRFN3 LRFN3 EFNB3 EFNB3 KCNC3 KCNC3 LRFN2 LRFN2 H0W649_CAVPO H0W649_CAVPO CHRM1 CHRM1 GRIK5 GRIK5 CHRM4 CHRM4 CHRNE CHRNE DRD5 DRD5 GABRE GABRE CHRNA10 CHRNA10 NLGN2 NLGN2 SLC6A3 SLC6A3 LRRC4B LRRC4B Drd4 Drd4 ADORA2A ADORA2A LRRC4 LRRC4 GABBR1 GABBR1 PCDH19 PCDH19 NPTN NPTN FXYD6 FXYD6 PTPRZ1 PTPRZ1 CACNG3 CACNG3 SHISA9 SHISA9 ADAM22 ADAM22 NTRK3 NTRK3 ADGRL2 ADGRL2 LRFN1 LRFN1 NRP2 NRP2 Rtn4 Rtn4 SHISA7 SHISA7 CLSTN1 CLSTN1 FLRT3 FLRT3 GRIN1 GRIN1 GRIN2D GRIN2D KCNA4 KCNA4 ENSCPOP00000027864 ENSCPOP00000027864 CNIH2 CNIH2 OPRD1 OPRD1 CHRNA1 CHRNA1 SLC8A3 SLC8A3 Chrna7 Chrna7 P2RX1 P2RX1 Prrt1 Prrt1 Chrnb2 Chrnb2 CLSTN2 CLSTN2 CHAD CHAD SLC6A9 SLC6A9 GRIK4 GRIK4 EFNB2 EFNB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CADM1Cell adhesion molecule 1. (475 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (705 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (819 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (505 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
DCCDCC netrin 1 receptor. (991 aa)
SLC1A6Amino acid transporter. (560 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (364 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
ADCY1Adenylate cyclase 1. (944 aa)
CDH9Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
CANXCalnexin. (593 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (888 aa)
EPHA7EPH receptor A7. (969 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (861 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
NCAM1Neural cell adhesion molecule 1. (848 aa)
SLITRK3SLIT and NTRK like family member 3. (964 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (719 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (581 aa)
GRM2Glutamate metabotropic receptor 2. (871 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1381 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (820 aa)
PLPPR4Phospholipid phosphatase related 4. (748 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (635 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1114 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
SLC6A11Solute carrier family 6 member 11. (640 aa)
HTR5A5-hydroxytryptamine receptor 5A. (356 aa)
CLSTN3Calsyntenin 3. (959 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1578 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (465 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (576 aa)
NECTIN3Nectin cell adhesion molecule 3. (546 aa)
NETO1Neuropilin and tolloid like 1. (450 aa)
LRRC7Leucine rich repeat containing 7. (1504 aa)
H0VF00_CAVPOUncharacterized protein. (323 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (840 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (521 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1908 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (930 aa)
GSG1LGSG1 like. (307 aa)
SLC1A7Amino acid transporter. (574 aa)
EPHB2EPH receptor B2. (949 aa)
EPHA4EPH receptor A4. (986 aa)
ERBB4Receptor protein-tyrosine kinase. (1263 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
Slc6a8Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (845 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (591 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2337 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (506 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (594 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (381 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1805 aa)
LOC100730761Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (696 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1462 aa)
SLC30A1Solute carrier family 30 member 1. (448 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
GRM3Glutamate metabotropic receptor 3. (877 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1052 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
PTPRTProtein tyrosine phosphatase receptor type T. (1395 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (502 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa)
PCDH8Protocadherin 8. (1070 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1876 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (528 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
SLC16A3Solute carrier family 16 member 3. (465 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (325 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (589 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (626 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (729 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (791 aa)
H0W649_CAVPOVoltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (892 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (474 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (447 aa)
NLGN2Neuroligin 2. (662 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
LRRC4BLeucine rich repeat containing 4B. (607 aa)
Drd4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa)
ADORA2AAdenosine receptor A2a; Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). (409 aa)
LRRC4Leucine rich repeat containing 4. (652 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (844 aa)
PCDH19Protocadherin 19. (1147 aa)
NPTNNeuroplastin. (397 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (1433 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
SHISA9Shisa family member 9. (424 aa)
ADAM22ADAM metallopeptidase domain 22. (928 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
ADGRL2Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1456 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (771 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
Rtn4Reticulon. (350 aa)
SHISA7Shisa family member 7. (377 aa)
CLSTN1Calsyntenin 1. (989 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (808 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (622 aa)
ENSCPOP00000027864Uncharacterized protein. (121 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (457 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
Chrna7Uncharacterized protein. (483 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
Prrt1Uncharacterized protein. (83 aa)
Chrnb2Uncharacterized protein. (499 aa)
CLSTN2Calsyntenin 2. (956 aa)
CHADChondroadherin. (359 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (633 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (295 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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