STRINGSTRING
RBSN RBSN MTMR4 MTMR4 RUFY2 RUFY2 ANKFY1 ANKFY1 WDFY3 WDFY3 FYCO1 FYCO1 Zfyve16 Zfyve16 RUFY1 RUFY1 FGD6 FGD6 FGD5 FGD5 ZFYVE1 ZFYVE1 ZFYVE19 ZFYVE19 EEA1 EEA1 WDFY2 WDFY2 ZFYVE28 ZFYVE28 ZFYVE21 ZFYVE21 HGS HGS ZFYVE26 ZFYVE26 PLEKHF1 PLEKHF1 PIKFYVE PIKFYVE MTMR3 MTMR3 FGD2 FGD2 FGD4 FGD4 ZFYVE9 ZFYVE9 PLEKHF2 PLEKHF2 FGD3 FGD3 Wdfy1 Wdfy1 FGD1 FGD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBSNRabenosyn, RAB effector. (789 aa)
MTMR4Myotubularin related protein 4. (1189 aa)
RUFY2RUN and FYVE domain containing 2. (585 aa)
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1169 aa)
WDFY3WD repeat and FYVE domain containing 3. (3526 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1440 aa)
Zfyve16FYVE-type domain-containing protein. (1562 aa)
RUFY1RUN and FYVE domain containing 1. (694 aa)
FGD6FYVE, RhoGEF and PH domain containing 6. (1400 aa)
FGD5FYVE, RhoGEF and PH domain containing 5. (1438 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (777 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (390 aa)
EEA1Early endosome antigen 1. (1377 aa)
WDFY2WD repeat and FYVE domain containing 2. (400 aa)
ZFYVE28Zinc finger FYVE-type containing 28. (882 aa)
ZFYVE21Zinc finger FYVE-type containing 21. (234 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (778 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2540 aa)
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (278 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2079 aa)
MTMR3Myotubularin related protein 3. (1221 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (627 aa)
FGD4FYVE, RhoGEF and PH domain containing 4. (904 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1322 aa)
PLEKHF2Pleckstrin homology and FYVE domain containing 2. (248 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (726 aa)
Wdfy1Uncharacterized protein. (410 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (952 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.