STRINGSTRING
PKD1 PKD1 DENND5B DENND5B LIPG LIPG LOXHD1 LOXHD1 DENND5A DENND5A LOC100719677 LOC100719677 PKDREJ PKDREJ ALOX5 ALOX5 ALOX15B ALOX15B PNLIP PNLIP ALOXE3 ALOXE3 ALOX12B ALOX12B PNLIPRP2 PNLIPRP2 LIPC LIPC LPL LPL ALOX12 ALOX12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKD1Polycystin 1, transient receptor potential channel interacting. (4283 aa)
DENND5BDENN domain containing 5B. (1231 aa)
LIPGLipase G, endothelial type. (498 aa)
LOXHD1Lipoxygenase homology domains 1. (2070 aa)
DENND5ADENN domain containing 5A. (1174 aa)
LOC100719677Uncharacterized protein. (662 aa)
PKDREJPolycystin family receptor for egg jelly. (2029 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (669 aa)
PNLIPPancreatic triacylglycerol lipase. (428 aa)
ALOXE3Arachidonate lipoxygenase 3. (711 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (700 aa)
PNLIPRP2Pancreatic lipase-related protein 2; Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. (451 aa)
LIPCLipase C, hepatic type. (497 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (495 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (656 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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