STRINGSTRING
MCM9 MCM9 VCP VCP KATNAL1 KATNAL1 Abcf2 Abcf2 NAV1 NAV1 ATAD1 ATAD1 RAD51D RAD51D ABCA3 ABCA3 PSMC1 PSMC1 LOC100716350 LOC100716350 ABCC9 ABCC9 LOC100716581 LOC100716581 LONP1 LONP1 ABCA6 ABCA6 ENSCPOP00000028693 ENSCPOP00000028693 TOR4A TOR4A Mcm8 Mcm8 KATNA1 KATNA1 AFG3L2 AFG3L2 Nsf Nsf CLPB CLPB TOR2A TOR2A DNAH6 DNAH6 PSMC3 PSMC3 ABCB10 ABCB10 ABCA5 ABCA5 NVL NVL LOC100716628 LOC100716628 Tap2 Tap2 CLPX CLPX LOC100732684 LOC100732684 MCM7 MCM7 FIGNL1 FIGNL1 ABCF1 ABCF1 ABCG5 ABCG5 RUVBL2 RUVBL2 ABCB9 ABCB9 H0W6Z4_CAVPO H0W6Z4_CAVPO H0W664_CAVPO H0W664_CAVPO FIGNL2 FIGNL2 NUBP1 NUBP1 RFC5 RFC5 FIGN FIGN TAP1 TAP1 ATAD3A ATAD3A NAV2 NAV2 PSMC2 PSMC2 H0VW21_CAVPO H0VW21_CAVPO H0VVZ8_CAVPO H0VVZ8_CAVPO MDN1 MDN1 ABCA4 ABCA4 ABCG1 ABCG1 ABCC4 ABCC4 DNAH5 DNAH5 SRPRA SRPRA LOC100723442 LOC100723442 ABCA2 ABCA2 VPS4B VPS4B DMC1 DMC1 ATAD2B ATAD2B RAD51 RAD51 ASCC3 ASCC3 DNAH10 DNAH10 ABCC3 ABCC3 DNAH9 DNAH9 CFTR CFTR WRNIP1 WRNIP1 ABCF3 ABCF3 Abcb1 Abcb1 RFC2 RFC2 ABCA9 ABCA9 ATAD5 ATAD5 ABCD1 ABCD1 PSMC5 PSMC5 ABCC5 ABCC5 RFC4 RFC4 ABCC2 ABCC2 RAD51B RAD51B ABCB7 ABCB7 CDC6 CDC6 ABCD2 ABCD2 CHTF18 CHTF18 ABCA7 ABCA7 DNAH8 DNAH8 ABCC10 ABCC10 RUVBL1 RUVBL1 PSMC6 PSMC6 ABCA1 ABCA1 H0VDV0_CAVPO H0VDV0_CAVPO DNAH3 DNAH3 PEX6 PEX6 SPAST SPAST NTPCR NTPCR ORC4 ORC4 SPATA5L1 SPATA5L1 H0VC48_CAVPO H0VC48_CAVPO KATNAL2 KATNAL2 Atad2 Atad2 ABCE1 ABCE1 PEX1 PEX1 IGHMBP2 IGHMBP2 ABCC12 ABCC12 ABCG4 ABCG4 VWA8 VWA8 ABCA12 ABCA12 ABCB11 ABCB11 SPATA5 SPATA5 ORC1 ORC1 ABCC6 ABCC6 ABCC1 ABCC1 ABCD4 ABCD4 ABCB6 ABCB6 ABCB8 ABCB8 DNAH2 DNAH2 GPN1 GPN1 RFC1 RFC1 TRIP13 TRIP13 DYNC1H1 DYNC1H1 PSMC4 PSMC4 LONP2 LONP2 Vps4a Vps4a SRP54 SRP54 DNAH11 DNAH11 SPG7 SPG7 ABCB5 ABCB5 BCS1L BCS1L ABCD3 ABCD3 ABCC8 ABCC8 LOC100733451 LOC100733451 DNAH7 DNAH7 MCM3 MCM3 ABCG8 ABCG8
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1117 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
Abcf2Uncharacterized protein. (625 aa)
NAV1Neuron navigator 1. (2146 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
RAD51DDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (329 aa)
ABCA3ATP binding cassette subfamily A member 3. (1704 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
LOC100716350ABC transporter domain-containing protein. (658 aa)
ABCC9ATP binding cassette subfamily C member 9. (1546 aa)
LOC100716581ABC transporter domain-containing protein. (656 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (1003 aa)
ABCA6ATP binding cassette subfamily A member 6. (1465 aa)
ENSCPOP00000028693Uncharacterized protein. (2251 aa)
TOR4ATorsin family 4 member A. (413 aa)
Mcm8MCM domain-containing protein; Belongs to the MCM family. (833 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (492 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (809 aa)
NsfUncharacterized protein. (748 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (705 aa)
TOR2ATorsin. (321 aa)
DNAH6Dynein axonemal heavy chain 6. (4152 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
ABCB10ATP binding cassette subfamily B member 10. (711 aa)
ABCA5ATP binding cassette subfamily A member 5. (1593 aa)
NVLNuclear VCP like. (849 aa)
LOC100716628ABC transporter domain-containing protein. (658 aa)
Tap2Uncharacterized protein. (703 aa)
CLPXCaseinolytic mitochondrial matrix peptidase chaperone subunit. (633 aa)
LOC100732684Uncharacterized protein. (1219 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (676 aa)
ABCF1ATP binding cassette subfamily F member 1. (775 aa)
ABCG5ATP binding cassette subfamily G member 5. (480 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (486 aa)
ABCB9ATP binding cassette subfamily B member 9. (766 aa)
H0W6Z4_CAVPOUncharacterized protein. (750 aa)
H0W664_CAVPOUncharacterized protein. (1232 aa)
FIGNL2Fidgetin like 2. (636 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (323 aa)
RFC5Replication factor C subunit 5. (340 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (762 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (725 aa)
ATAD3AATPase family AAA domain containing 3A. (584 aa)
NAV2Neuron navigator 2. (2385 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
H0VW21_CAVPOABC transporter domain-containing protein. (632 aa)
H0VVZ8_CAVPOABC transporter domain-containing protein. (662 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5563 aa)
ABCA4ATP binding cassette subfamily A member 4. (2270 aa)
ABCG1ATP binding cassette subfamily G member 1. (666 aa)
ABCC4ATP binding cassette subfamily C member 4. (1324 aa)
DNAH5Dynein axonemal heavy chain 5. (4602 aa)
SRPRASRP receptor subunit alpha. (637 aa)
LOC100723442ABC transporter domain-containing protein. (659 aa)
ABCA2ATP binding cassette subfamily A member 2. (2427 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa)
ATAD2BATPase family AAA domain containing 2B. (1404 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2185 aa)
DNAH10Dynein axonemal heavy chain 10. (4513 aa)
ABCC3ATP binding cassette subfamily C member 3. (1523 aa)
DNAH9Dynein axonemal heavy chain 9. (4438 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
WRNIP1WRN helicase interacting protein 1. (568 aa)
ABCF3ATP binding cassette subfamily F member 3. (722 aa)
Abcb1Uncharacterized protein. (1243 aa)
RFC2Replication factor C subunit 2. (352 aa)
ABCA9ATP binding cassette subfamily A member 9. (1579 aa)
ATAD5ATPase family AAA domain containing 5. (1831 aa)
ABCD1ATP binding cassette subfamily D member 1. (723 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
RFC4Replication factor C subunit 4. (363 aa)
ABCC2ATP binding cassette subfamily C member 2. (1537 aa)
RAD51BRAD51 paralog B. (258 aa)
ABCB7ATP binding cassette subfamily B member 7. (752 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (579 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
CHTF18Chromosome transmission fidelity factor 18. (988 aa)
ABCA7ATP binding cassette subfamily A member 7. (2108 aa)
DNAH8Dynein axonemal heavy chain 8. (4707 aa)
ABCC10ATP binding cassette subfamily C member 10. (1486 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
ABCA1ATP binding cassette subfamily A member 1. (2200 aa)
H0VDV0_CAVPOUncharacterized protein. (4156 aa)
DNAH3Dynein axonemal heavy chain 3. (3996 aa)
PEX6Peroxisomal biogenesis factor 6. (982 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
NTPCRNucleoside-triphosphatase, cancer-related. (190 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (419 aa)
SPATA5L1Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family. (634 aa)
H0VC48_CAVPOABC transporter domain-containing protein. (590 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (540 aa)
Atad2Bromo domain-containing protein. (1361 aa)
ABCE1ATP binding cassette subfamily E member 1. (599 aa)
PEX1Peroxisomal biogenesis factor 1. (1271 aa)
IGHMBP2Immunoglobulin mu DNA binding protein 2. (1051 aa)
ABCC12ATP binding cassette subfamily C member 12. (1365 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
VWA8Von Willebrand factor A domain containing 8. (1906 aa)
ABCA12ATP binding cassette subfamily A member 12. (2597 aa)
ABCB11Uncharacterized protein. (1320 aa)
SPATA5Spermatogenesis associated 5. (884 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (837 aa)
ABCC6ATP binding cassette subfamily C member 6. (1436 aa)
ABCC1ATP binding cassette subfamily C member 1. (1531 aa)
ABCD4ATP binding cassette subfamily D member 4. (602 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa)
ABCB8ATP binding cassette subfamily B member 8. (720 aa)
DNAH2Dynein axonemal heavy chain 2. (4387 aa)
GPN1GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (373 aa)
RFC1Replication factor C subunit 1. (1153 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4637 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
Vps4aUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (503 aa)
DNAH11Dynein axonemal heavy chain 11. (4501 aa)
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (802 aa)
ABCB5ATP binding cassette subfamily B member 5. (1202 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (418 aa)
ABCD3ATP binding cassette subfamily D member 3. (611 aa)
ABCC8ATP binding cassette subfamily C member 8. (1549 aa)
LOC100733451AAA domain-containing protein. (805 aa)
DNAH7Dynein axonemal heavy chain 7. (4015 aa)
MCM3DNA helicase; Belongs to the MCM family. (810 aa)
ABCG8ATP binding cassette subfamily G member 8. (658 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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