46 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TCF7L1	Transcription factor 7 like 1. (587 aa)
	SOX5	SRY-box transcription factor 5. (763 aa)
	SOX18	SRY-box transcription factor 18. (375 aa)
	SOX11	Transcription factor SOX. (377 aa)
	TOX4	TOX high mobility group box family member 4. (619 aa)
	Sox4	HMG box domain-containing protein. (227 aa)
	H0WAS6_CAVPO	Uncharacterized protein. (214 aa)
	TCF7	Transcription factor 7. (262 aa)
	SOX14	SRY-box transcription factor 14. (240 aa)
	SOX12	Transcription factor SOX. (310 aa)
	SOX10	SRY-box transcription factor 10. (469 aa)
	SOX3	SRY-box transcription factor 3. (449 aa)
	BBX	BBX high mobility group box domain containing. (940 aa)
	TCF7L2	Transcription factor 7 like 2. (350 aa)
	LEF1	Lymphoid enhancer binding factor 1. (396 aa)
	PMS1	PMS1 homolog 1, mismatch repair system component. (930 aa)
	SOX7	SRY-box transcription factor 7. (384 aa)
	HMGB3	High mobility group box 3. (202 aa)
	CIC	Capicua transcriptional repressor. (2524 aa)
	TFAM	Transcription factor A, mitochondrial. (235 aa)
	ENSCPOP00000032088	Uncharacterized protein. (191 aa)
	ENSCPOP00000032429	HMG box domain-containing protein. (565 aa)
	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
	PBRM1	Polybromo 1. (1704 aa)
	SOX30	SRY-box transcription factor 30. (767 aa)
	SSRP1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
	SOX17	SRY-box transcription factor 17. (400 aa)
	HBP1	HMG-box transcription factor 1. (523 aa)
	HMGXB3	HMG-box containing 3. (1280 aa)
	SOX8	SRY-box transcription factor 8. (462 aa)
	KMT2D	Lysine methyltransferase 2D. (5430 aa)
	H0V021_CAVPO	HMG box domain-containing protein. (565 aa)
	WDHD1	WD repeat and HMG-box DNA binding protein 1. (1118 aa)
	HMGB2	High mobility group box 2. (211 aa)
	SOX15	SRY-box transcription factor 15. (216 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (419 aa)
	HMGXB4	HMG-box containing 4. (585 aa)
	SOX13	SRY-box transcription factor 13. (617 aa)
	NSD2	Nuclear receptor binding SET domain protein 2. (1366 aa)
	HMGB4	High mobility group box 4. (184 aa)
	UBTF	Upstream binding transcription factor. (763 aa)
	TOX2	TOX high mobility group box family member 2. (535 aa)
	HMG20B	High mobility group 20B. (318 aa)
	TOX	Thymocyte selection associated high mobility group box. (526 aa)
	HMG20A	High mobility group 20A. (347 aa)
	SOX6	SRY-box transcription factor 6. (859 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCPOP00000032088	HMGB2	ENSCPOP00000032088	ENSCPOP00000003209	Uncharacterized protein.	High mobility group box 2.	0.822
ENSCPOP00000032088	HMGB4	ENSCPOP00000032088	ENSCPOP00000006810	Uncharacterized protein.	High mobility group box 4.	0.821
ENSCPOP00000032088	SMARCE1	ENSCPOP00000032088	ENSCPOP00000000150	Uncharacterized protein.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.614
ENSCPOP00000032088	SSRP1	ENSCPOP00000032088	ENSCPOP00000000423	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.521
ENSCPOP00000032429	LEF1	ENSCPOP00000032429	ENSCPOP00000023567	HMG box domain-containing protein.	Lymphoid enhancer binding factor 1.	0.470
ENSCPOP00000032429	TCF7	ENSCPOP00000032429	ENSCPOP00000021020	HMG box domain-containing protein.	Transcription factor 7.	0.470
ENSCPOP00000032429	TCF7L1	ENSCPOP00000032429	ENSCPOP00000013058	HMG box domain-containing protein.	Transcription factor 7 like 1.	0.470
ENSCPOP00000032429	TCF7L2	ENSCPOP00000032429	ENSCPOP00000022558	HMG box domain-containing protein.	Transcription factor 7 like 2.	0.470
H0V021_CAVPO	SSRP1	ENSCPOP00000002800	ENSCPOP00000000423	HMG box domain-containing protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.520
H0WAS6_CAVPO	HMGB2	ENSCPOP00000020089	ENSCPOP00000003209	Uncharacterized protein.	High mobility group box 2.	0.820
H0WAS6_CAVPO	HMGB4	ENSCPOP00000020089	ENSCPOP00000006810	Uncharacterized protein.	High mobility group box 4.	0.818
H0WAS6_CAVPO	SMARCE1	ENSCPOP00000020089	ENSCPOP00000000150	Uncharacterized protein.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.614
H0WAS6_CAVPO	SSRP1	ENSCPOP00000020089	ENSCPOP00000000423	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.521
HMG20A	HMG20B	ENSCPOP00000010527	ENSCPOP00000009676	High mobility group 20A.	High mobility group 20B.	0.889
HMG20A	SMARCE1	ENSCPOP00000010527	ENSCPOP00000000150	High mobility group 20A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.406
HMG20A	SSRP1	ENSCPOP00000010527	ENSCPOP00000000423	High mobility group 20A.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.520
HMG20B	HMG20A	ENSCPOP00000009676	ENSCPOP00000010527	High mobility group 20B.	High mobility group 20A.	0.889
HMG20B	SSRP1	ENSCPOP00000009676	ENSCPOP00000000423	High mobility group 20B.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.520
HMGB2	ENSCPOP00000032088	ENSCPOP00000003209	ENSCPOP00000032088	High mobility group box 2.	Uncharacterized protein.	0.822
HMGB2	H0WAS6_CAVPO	ENSCPOP00000003209	ENSCPOP00000020089	High mobility group box 2.	Uncharacterized protein.	0.820