13 items (Cavia porcellus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	H0W0J6_CAVPO	Uncharacterized protein. (384 aa)
	ZADH2	Zinc binding alcohol dehydrogenase domain containing 2. (307 aa)
	PTGR1	Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. (287 aa)
	H0WCC9_CAVPO	Uncharacterized protein. (384 aa)
	LOC100727028	PKS_ER domain-containing protein. (382 aa)
	ADH5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (367 aa)
	MECR	Mitochondrial trans-2-enoyl-CoA reductase. (373 aa)
	Ptgr2	Uncharacterized protein. (350 aa)
	LOC100734190	Uncharacterized protein. (369 aa)
	LOC100732008	PKS_ER domain-containing protein. (375 aa)
	CRYZ	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding. (329 aa)
	FASN	Fatty acid synthase. (2530 aa)
	SORD	Sorbitol dehydrogenase. (357 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADH5	CRYZ	ENSCPOP00000028740	ENSCPOP00000005873	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	0.417
ADH5	LOC100732008	ENSCPOP00000028740	ENSCPOP00000006333	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	PKS_ER domain-containing protein.	0.801
ADH5	MECR	ENSCPOP00000028740	ENSCPOP00000028796	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Mitochondrial trans-2-enoyl-CoA reductase.	0.416
ADH5	SORD	ENSCPOP00000028740	ENSCPOP00000002033	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Sorbitol dehydrogenase.	0.650
ADH5	ZADH2	ENSCPOP00000028740	ENSCPOP00000019195	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Zinc binding alcohol dehydrogenase domain containing 2.	0.417
CRYZ	ADH5	ENSCPOP00000005873	ENSCPOP00000028740	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.417
CRYZ	FASN	ENSCPOP00000005873	ENSCPOP00000002086	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	Fatty acid synthase.	0.835
CRYZ	H0W0J6_CAVPO	ENSCPOP00000005873	ENSCPOP00000016483	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	Uncharacterized protein.	0.417
CRYZ	H0WCC9_CAVPO	ENSCPOP00000005873	ENSCPOP00000020649	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	Uncharacterized protein.	0.417
CRYZ	LOC100727028	ENSCPOP00000005873	ENSCPOP00000027859	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	PKS_ER domain-containing protein.	0.417
CRYZ	LOC100732008	ENSCPOP00000005873	ENSCPOP00000006333	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	PKS_ER domain-containing protein.	0.417
CRYZ	LOC100734190	ENSCPOP00000005873	ENSCPOP00000017713	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	Uncharacterized protein.	0.417
CRYZ	SORD	ENSCPOP00000005873	ENSCPOP00000002033	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	Sorbitol dehydrogenase.	0.645
FASN	CRYZ	ENSCPOP00000002086	ENSCPOP00000005873	Fatty acid synthase.	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	0.835
FASN	MECR	ENSCPOP00000002086	ENSCPOP00000028796	Fatty acid synthase.	Mitochondrial trans-2-enoyl-CoA reductase.	0.916
FASN	PTGR1	ENSCPOP00000002086	ENSCPOP00000019699	Fatty acid synthase.	Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.	0.429
FASN	Ptgr2	ENSCPOP00000002086	ENSCPOP00000032437	Fatty acid synthase.	Uncharacterized protein.	0.513
FASN	SORD	ENSCPOP00000002086	ENSCPOP00000002033	Fatty acid synthase.	Sorbitol dehydrogenase.	0.513
FASN	ZADH2	ENSCPOP00000002086	ENSCPOP00000019195	Fatty acid synthase.	Zinc binding alcohol dehydrogenase domain containing 2.	0.835
H0W0J6_CAVPO	CRYZ	ENSCPOP00000016483	ENSCPOP00000005873	Uncharacterized protein.	Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.	0.417