STRINGSTRING
UTP15 UTP15 GNB5 GNB5 Coro7 Coro7 EML5 EML5 RRP9 RRP9 DDB2 DDB2 NLE1 NLE1 DCAF13 DCAF13 STRN STRN EIF3I EIF3I NUP37 NUP37 TRAF7 TRAF7 WDR18 WDR18 LYST LYST WDR72 WDR72 Cdc40 Cdc40 Nup43 Nup43 H0VHP2_CAVPO H0VHP2_CAVPO Prpf4 Prpf4 KIF21A KIF21A WSB1 WSB1 CORO1B CORO1B TLE4 TLE4 BRWD3 BRWD3 WDR55 WDR55 RAE1 RAE1 WDR12 WDR12 RACK1 RACK1 WDSUB1 WDSUB1 STXBP5L STXBP5L WDR7 WDR7 Tbl1x Tbl1x SEC31B SEC31B FBXW9 FBXW9 WDFY3 WDFY3 PHIP PHIP KATNB1 KATNB1 CHAF1B CHAF1B SMU1 SMU1 TBL3 TBL3 HERC1 HERC1 EIPR1 EIPR1 GNB1 GNB1 BTRC BTRC TBL1XR1 TBL1XR1 BOP1 BOP1 TAF5 TAF5 WDR1 WDR1 Ercc8 Ercc8 SNRNP40 SNRNP40 GTF3C2 GTF3C2 PLRG1 PLRG1 GEMIN5 GEMIN5 WDHD1 WDHD1 CORO2A CORO2A WDFY2 WDFY2 WDR90 WDR90 WDR83 WDR83 AAMP AAMP LOC100724915 LOC100724915 MLST8 MLST8 EED EED KIF21B KIF21B LRWD1 LRWD1 CORO1C CORO1C DCAF12 DCAF12 WDR41 WDR41 WDR47 WDR47 STRN4 STRN4 DPH7 DPH7 Cfap52 Cfap52 SCAP SCAP WDFY4 WDFY4 GNB3 GNB3 GNB2 GNB2 Pwp2 Pwp2 WDR86 WDR86 TAF5L TAF5L WDR61 WDR61 STRN3 STRN3 POC1B POC1B Rbbp4 Rbbp4 WDR24 WDR24 FBXW11 FBXW11 POC1A POC1A TLE2 TLE2 THOC6 THOC6 PWP1 PWP1 PAK1IP1 PAK1IP1 TBL2 TBL2 CORO1A CORO1A WDR31 WDR31 AMBRA1 AMBRA1 WDR59 WDR59 DAW1 DAW1 NEDD1 NEDD1 ATG16L1 ATG16L1 WDR5 WDR5 WDR17 WDR17 COP1 COP1 CIAO1 CIAO1 FBXW7 FBXW7 ENSCPOP00000026334 ENSCPOP00000026334 TLE1 TLE1 RBBP7 RBBP7 Wdfy1 Wdfy1 PEX7 PEX7 ENSCPOP00000025354 ENSCPOP00000025354 GNB4 GNB4 CORO6 CORO6 ENSCPOP00000024706 ENSCPOP00000024706 WDR3 WDR3 WDR48 WDR48 WDR36 WDR36 DCAF7 DCAF7 COPA COPA ENSCPOP00000023240 ENSCPOP00000023240 FZR1 FZR1 FBXW2 FBXW2 PAFAH1B1 PAFAH1B1 CSTF1 CSTF1 PRPF19 PRPF19 Wdr5b Wdr5b CORO2B CORO2B WDR53 WDR53 WDR77 WDR77 TLE3 TLE3 H0W6R4_CAVPO H0W6R4_CAVPO APAF1 APAF1 DTL DTL WDR11 WDR11 WSB2 WSB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UTP15UTP15 small subunit processome component. (517 aa)
GNB5G protein subunit beta 5. (406 aa)
Coro7Coronin; Belongs to the WD repeat coronin family. (923 aa)
EML5EMAP like 5. (1945 aa)
RRP9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (472 aa)
DDB2Damage specific DNA binding protein 2. (289 aa)
NLE1Notchless homolog 1. (485 aa)
DCAF13DDB1 and CUL4 associated factor 13. (445 aa)
STRNStriatin. (780 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
NUP37Nucleoporin 37. (326 aa)
TRAF7TNF receptor associated factor 7. (670 aa)
WDR18WD repeat domain 18. (429 aa)
LYSTLysosomal trafficking regulator. (3688 aa)
WDR72WD repeat domain 72. (1071 aa)
Cdc40WD_REPEATS_REGION domain-containing protein. (579 aa)
Nup43WD_REPEATS_REGION domain-containing protein. (378 aa)
H0VHP2_CAVPOWD_REPEATS_REGION domain-containing protein. (601 aa)
Prpf4WD_REPEATS_REGION domain-containing protein. (521 aa)
KIF21AKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1631 aa)
WSB1WD repeat and SOCS box containing 1. (421 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (486 aa)
TLE4TLE family member 4, transcriptional corepressor. (758 aa)
BRWD3Bromodomain and WD repeat domain containing 3. (1700 aa)
WDR55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (380 aa)
RAE1Ribonucleic acid export 1. (368 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
WDSUB1WD repeat, sterile alpha motif and U-box domain containing 1. (476 aa)
STXBP5LSyntaxin binding protein 5 like. (1098 aa)
WDR7WD repeat domain 7. (1453 aa)
Tbl1xUncharacterized protein. (526 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1117 aa)
FBXW9F-box and WD repeat domain containing 9. (457 aa)
WDFY3WD repeat and FYVE domain containing 3. (3526 aa)
PHIPPleckstrin homology domain interacting protein. (1704 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
CHAF1BChromatin assembly factor 1 subunit B. (508 aa)
SMU1SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
TBL3Transducin beta like 3. (800 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4568 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (387 aa)
GNB1Beta-transducin. (340 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (582 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (504 aa)
BOP1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (734 aa)
TAF5TATA-box binding protein associated factor 5. (762 aa)
WDR1WD_REPEATS_REGION domain-containing protein. (600 aa)
Ercc8WD_REPEATS_REGION domain-containing protein. (396 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (358 aa)
GTF3C2General transcription factor IIIC subunit 2. (910 aa)
PLRG1Pleiotropic regulator 1. (515 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1554 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1. (1118 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (549 aa)
WDFY2WD repeat and FYVE domain containing 2. (400 aa)
WDR90WD repeat domain 90. (1847 aa)
WDR83WD repeat domain 83. (315 aa)
AAMPAngio associated migratory cell protein. (436 aa)
LOC100724915Uncharacterized protein. (621 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
EEDEmbryonic ectoderm development. (417 aa)
KIF21BKinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1637 aa)
LRWD1Leucine rich repeats and WD repeat domain containing 1. (642 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
DCAF12DDB1 and CUL4 associated factor 12. (371 aa)
WDR41WD repeat domain 41. (462 aa)
WDR47WD repeat domain 47. (919 aa)
STRN4Striatin 4. (777 aa)
DPH7Diphthamide biosynthesis 7. (446 aa)
Cfap52WD_REPEATS_REGION domain-containing protein. (580 aa)
SCAPSREBF chaperone. (1260 aa)
WDFY4WDFY family member 4. (3256 aa)
GNB3G protein subunit beta 3. (340 aa)
GNB2G protein subunit beta 2. (378 aa)
Pwp2Uncharacterized protein. (924 aa)
WDR86WD repeat domain 86. (374 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
WDR61WD repeat domain 61. (305 aa)
STRN3Striatin 3. (786 aa)
POC1BPOC1 centriolar protein B. (478 aa)
Rbbp4WD_REPEATS_REGION domain-containing protein. (425 aa)
WDR24WD repeat domain 24. (790 aa)
FBXW11F-box and WD repeat domain containing 11. (530 aa)
POC1APOC1 centriolar protein A. (407 aa)
TLE2TLE family member 2, transcriptional corepressor. (663 aa)
THOC6THO complex 6. (341 aa)
PWP1PWP1 homolog, endonuclein. (500 aa)
PAK1IP1PAK1 interacting protein 1. (387 aa)
TBL2Transducin beta like 2. (443 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
WDR31WD repeat domain 31. (366 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1291 aa)
WDR59WD repeat domain 59. (983 aa)
DAW1Dynein assembly factor with WD repeats 1. (415 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (691 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
WDR5WD repeat domain 5. (334 aa)
WDR17WD repeat domain 17. (1164 aa)
COP1COP1 E3 ubiquitin ligase. (798 aa)
CIAO1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (336 aa)
FBXW7F-box and WD repeat domain containing 7. (711 aa)
ENSCPOP00000026334WD_REPEATS_REGION domain-containing protein. (385 aa)
TLE1TLE family member 1, transcriptional corepressor. (798 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
Wdfy1Uncharacterized protein. (410 aa)
PEX7Peroxisomal biogenesis factor 7. (319 aa)
ENSCPOP00000025354WD_REPEATS_REGION domain-containing protein. (312 aa)
GNB4G protein subunit beta 4. (340 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (472 aa)
ENSCPOP00000024706WD_REPEATS_REGION domain-containing protein. (357 aa)
WDR3WD repeat domain 3. (943 aa)
WDR48WD repeat domain 48. (676 aa)
WDR36WD repeat domain 36. (909 aa)
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa)
ENSCPOP00000023240WD_REPEATS_REGION domain-containing protein. (512 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
FBXW2F-box and WD repeat domain containing 2. (454 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
PRPF19Pre-mRNA processing factor 19. (513 aa)
Wdr5bWD_REPEATS_REGION domain-containing protein. (324 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (477 aa)
WDR53WD repeat domain 53. (360 aa)
WDR77WD repeat domain 77. (342 aa)
TLE3TLE family member 3, transcriptional corepressor. (769 aa)
H0W6R4_CAVPOWD_REPEATS_REGION domain-containing protein. (418 aa)
APAF1Apoptotic peptidase activating factor 1. (1265 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (734 aa)
WDR11WD repeat domain 11. (1224 aa)
WSB2WD repeat and SOCS box containing 2. (406 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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